| 영문 | gene | 한글 | 유전자 |
|---|---|---|---|
| 설명 | 유전자는 길게 띠를 형성한 DNA분자의 일부분으로 한 가지 물질을 만드는데 필요한 모든 정보를 갖춘 기능적인 단위이다. 예를 들어 인슐린이라는 물질의 유전자라고 하면 사람의 세포내에 있는 긴 DNA 분자 중에서 인슐린이라는 물질을 만드는데 필요한 모든 정보를 가지고 있는 한 부분을 가리키는 말이다. 고전적인 생물학에서는 유전자가 표현형을 결정하거나 지정하는 염색체의 일부분이라고 정의되었지만, 오늘날에는 유전자에 대해서 분자적 정의가 제안되고 있으며 그 정의는 하나의 유전자는 하나의 효소를 결정 또는 암호화하는 유전물질의 일부분이라는 개념으로 이것이 이른바 1개의 유전자 1개 효소가설(one gene-one enzyme hypothesis)이다. 즉 1개의 유전자는 1개의 효소를 제작하는데 필요한 유전정보를 가진다는 것이다. 현재 이 가설이 받아들여지고 있다. |
||
| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
||
| HGM | hog gastric mucosa; human gene mapping; human glucose monitoring |
|---|---|
| EMT | emergency medical tag; emergency medical team; emergency medical technician; emergency medical treat... |
| CGRP | Calcitonin Gene Related Peptide(Protein) |
| CGRPs | Calcitonin Gene-Related Products |
| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
| BSPM | Body surface potential mapping |
|---|---|
| CFM | Color-flow mapping |
| SPM | Statistical Parametric Mapping |
| SPM96 | Statistical Parametric Mapping |
| CM | consistent mapping |
| mapping, gene | Charting the positions of genes on chromosome and learning the distance, in linkage units or physical units, between genes. (12 Dec 1998) |
|---|
| gene mapping | Determination of the relative positions of genes on a DNA molecule (chromosome or plasmid) and of the distance, in linkage units or physical units, between them. (09 Oct 1997) |
|---|---|
| body surface potential mapping | Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in wolff-parkinson-white syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (12 Dec 1998) |
| cardiac mapping | A method by which local cardiac potentials are spatially depicted in an integrated manner as a function of time (isochrone map) or potential (isopotential map). (05 Mar 2000) |
| mapping | See: gene mapping, linkage map, physical map. (09 Oct 1997) |
| mapping function | In linkage analysis, a formula that converts the recombination fraction (which is on the probability scale) into map distance (in morgans). (05 Mar 2000) |
| genetic mapping | Determination of the relative positions of genes on a DNA molecule (chromosome or plasmid) and of the distance, in linkage units or physical units, between them. (14 Nov 1997) |
| restriction mapping | Use of restriction endonucleases to analyze and generate a physical map of genomes or genes. The nucleotide sequence determined is often then translated into an amino acid sequence, providing a means for sequencing the protein for which the gene codes, or for which the mRNA is a messenger. (12 Dec 1998) |
| peptide mapping | Two-dimensional separation and analysis of peptides. (12 Dec 1998) |
| chromosome mapping | The mapping of the relative locations of genes on a chromosome by analysing linkage frequencies (how often different genes are inherited together) and crossover frequencies (how often different combinations of three or more genes are inherited) or recombination frequencies. (09 Oct 1997) |
| S1 nuclease mapping | A method for locating the 5' end of a transcript in a mixture of RNA. (05 Mar 2000) |
| heteroduplex mapping | <molecular biology> Heteroduplex mapping is a lab technique used to locate a particular sequence of nucleotides. It involves making a heteroduplex by pairing the unknown nucleic acid strand with a reference strand which has a known sequence. (09 Oct 1997) |
| nucleotide mapping | Two-dimensional separation and analysis of nucleotides. (12 Dec 1998) |
| epitope mapping | Methods used for studying the interactions of antibodies with specific regions of protein antigens. Important applications of epitope mapping are found within the area of immunochemistry. (12 Dec 1998) |
| fine structure mapping | A technique of DNA mapping which makes use of extremely rare recombination events where the crossing over occurs between two genes or two alleles of a gene that are only a few nucleotides apart. (09 Oct 1997) |
| allelic gene | See: allele, dominance of traits. (05 Mar 2000) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|