| ¿µ¹® | malignant melanoma | ÇÑ±Û | ¾Ç¼ºÈæ»öÁ¾ |
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| ¿µ¹® | magnetic resonance imaging(MRI) | ÇÑ±Û | ÀÚ±â°ø¸í¿µ»ó |
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| ¼³¸í | ÀÎüÀÇ Àå±â³ª, º´ÀûÀÎ ¸ð¾ç, Á¾¾çÀÇ À§Ä¡, ¸²ÇÁÀýÀÇ ºñ´ë µî¿¡ ´ëÇÑ Áø´ÜÀ» ³»¸®±â À§ÇØ ½ÃÇàÇÏ´Â ¹æ»ç¼±ÇÐÀûÀÎ °Ë»ç¹æ¹ýÀÌ´Ù. ÇöÀç ¸¹ÀÌ ¾²À̰í ÀÖ´Â ÄÄÇ»ÅÍ´ÜÃþÃÔ¿µ¼ú(CT: computerized tomography)°ú´Â ´Ù¸¥ ¹æ¹ýÀ¸·Î ½ÃÇàÇϸç, ±× ÇØ»óµµ°¡ ÄÄÇ»ÅÍ´ÜÃþÃÔ¿µº¸´Ù´Â ¶Ù¾î³ª ºñ·Ï °í°¡À̱ä ÇÏÁö¸¸, ¸¹ÀÌ ¾²À̰í ÀÖ´Ù. ¶ÇÇÑ ÀÎü¿¡ ¹«ÇØÇϰí, ¿©·¯ °¡Áö ¸é¿¡¼ »ç¶÷À» ´ÜÃþÀ¸·Î ºÐ¸®½ÃÄÑ º¼ ¼ö ÀÖ´Â µî ÀåÁ¡ÀÌ ¸¹´Ù. ´ÜÁ¡Àº ½ÉÀå¹Úµ¿±â¸¦ ¼³Ä¡ÇÑ »ç¶÷À̳ª, ÁÖÀ§¿¡ ÀåÀ» ¶ì´Â ¹°Ã¼¸¦ ¸ö¿¡ Áö´Ï°í ÀÖ´Â ÁßȯÀÚ µî¿¡¼´Â ÀÌ¿ëÇÒ ¼ö ¾ø°í, º¹ºÎÀå±â¿¡ ´ëÇÑ Áø´Ü¿¡´Â ÄÄÇ»ÅÍ´ÜÃþÃÔ¿µº¸´Ù ºÒ¸®ÇÑ °ÍÀ¸·Î µÇ¾î ÀÖÀ¸¸ç, ¹«¾ùº¸´Ù ¼³Ä¡ºñ¿Í ±× ½Ã¼úºñ°¡ ºñ½Î´Ù´Âµ¥ °¡Àå Å« ´ÜÁ¡ÀÌ ÀÖ´Ù. |
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| ¿µ¹® | malignant tumor | ÇÑ±Û | ¾Ç¼ºÁ¾¾ç |
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| ¼³¸í | Á¤»óÀûÀÎ Á¶Á÷ ¼¼Æ÷°¡ °¢Á¾ ¹°¸®Àû-ÈÇÐÀû-»ý¹°ÇÐÀûÀÎ ¹ß¾Ï ¹°ÁúÀÇ ÀÛ¿ë ¶Ç´Â ¿äÀο¡ ÀÇÇØ µ¹¿¬º¯À̸¦ ÀÏÀ¸ÄѼ Çü¼ºµÇ´Â Á¾¾ç. ¹«Á¦ÇÑÀÇ ¼¼Æ÷ºÐ¿·Î ¸Å¿ì ¿Õ¼ºÇÏ°Ô Áõ½ÄÇÏ¿© ÁÖÀ§Á¶Á÷À» ÆÄ±«-ħ½ÄÇÑ´Ù. ¶Ç ¾î¶² ÈÇй°ÁúÀ» ³»¾î ÁÖÀ§ÀÇ Á¶Á÷¼¼Æ÷¸¦ Ä§ÇØÇÒ »Ó¸¸ ¾Æ´Ï¶ó, Ç÷°ü ¹× ¸²ÇÁ°üÀ» µû¶ó ÀüÀÌÇÏ¿© Àü½ÅÀÇ Ä«ÄʽþƸ¦ÀÏÀ¸ÄÑ Á×À½À» ÃÊ·¡ÇÑ´Ù. »óÇǼºÀÎ °ÍÀ» ¾ÏÁ¾À̶ó Çϰí, ºñ»óÇǼºÀÎ °ÍÀ» À°Á¾À̶ó ÇÑ´Ù. |
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| MM | macromolecule; Maelzels metronome; major medical [insurance]; malignant melanoma; manubrium to malle... |
|---|---|
| MH | malignant histiocytosis; malignant hyperpyrexia; malignant hypertension; malignant hyperthermia; mam... |
| MHS | major histocompatibility system; malignant hyperthermia in swine; malignant hyperthermia syndrome; m... |
| CMM | cell-mediated mutagenesis; cutaneous malignant melanoma |
| HCMM | hereditary cutaneous malignant melanoma |
| CMM | Cutaneous malignant melanoma |
|---|---|
| DMM | Desmoplastic Malignant Melanoma |
| MM | Malignant Melanoma |
| MMM | Metastatic malignant melanoma |
| 67Ga | Gallium |
| malignant melanoma: gallium imaging | <radiology> Greater than50% sensitivity for primary and metastatic sites: 73% sensitivity if lesion is greater than 2 cm, 17% sensitivity if less than 2 cm, see: gallium: indications malignant melanoma (12 Dec 1998) |
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| bone: gallium imaging | <radiology> Increased activity in: active osteomyelitis (90% sensitivity: better than Tc-99m MDP), sarcoma, cellulitis, septic arthritis, rheumatoid arthritis, Paget disease, metastases (65% sensitivity: than for bone agents) see: gallium: indications (12 Dec 1998) |
|---|---|
| neoplasm: gallium imaging | <radiology> Useful: Hodgkin disease and histiocytic form of NHL poor sensitivity below the diaphragm, Burkitt lymphoma: almost 100% sensitivity, hepatoma: 90% sensitivity, melanoma: 90% sensitivity, leukaemia possibly useful: NHL: good for large and mediastinal lesions, nodal metastases from seminoma and embryonal cell carcinoma: 87% sensitivity, non-small cell lung CA: 85% sensitive not useful: head and neck, GI (especially adenocarcinoma), breast, gynaecological, kiddie tumours see: gallium: indications (12 Dec 1998) |
| inflammation: gallium imaging | <radiology> Pathophysiology: leakage of protein-bound Ga-67 into extracellular space secondary to increased capillary permeability, Ga-67 is preferentially bound to nonviable PMNs and macrophages, leukocyte incorporation (rich in lactoferrin), bacterial uptake (siderophores), inflammtory tissue stimulates lactoferrin production for chronic abdominal inflammation: 67% sensitivity; 64% specificity; 13% false negatives; 5% false positive, dose: 5 mCi; imaging: 24, 48, 72 hours, diffuse uptake in peritonitis, localised uptake in acute pyogenic abscess, phlegmon, acute cholecystitis, acute pancreatitis, acute gastritis, diverticulitis, inflammatory bowel disease, surgical wound, pyelonephritis, perinephric abscess see: gallium indications, gallium vs. Indium (12 Dec 1998) |
| kidney: gallium imaging | <radiology> 10-20% of Ga-67 excreted via GU tract; no renal activity after 24hrs abnormal uptake (images at 48-72 hrs): tumour, primary renal tumour (variable uptake), lymphoma/leukaemia, metastases (e.g., melanoma), inflammation, acute pyelonephritis (88% sensitivity); abscess, lobar nephroma, others, collagen vascular disease, vasculitis, Wegener granulomatosis, amyloidosis, haemochromatosis, hepatic failure, antineoplastic drugs, transplant rejection: acute, chronic, ATN see also: gallium: indications (12 Dec 1998) |
| lung: gallium imaging | <radiology> Scans at 48 hrs because 50% of normals show activity at 24 hrs, focal uptake, primary pulmonary malignancy, benign disorder: granuloma, abscess, pneumonia, silicosis, multifocal/diffuse uptake, infection, TB: active lesion, miliary TB, rapidly progressive TB pneumonia, PCP: unimpressive symptoms and CXR, CMV, inflammation: sarcoid, interstitial lung disease (pneumoconiosis, idiopathic pulmonary fibrosis, lymphangitic carcinomatosis), radiation pneumonitis, drugs: bleomycin, amiodarone, contrast lymphangiography (in 50%) see: gallium: indications, uptake with normal chest film (12 Dec 1998) |
| cancer, malignant melanoma | A skin cancer that begins in cells called melanocytes that can grow together to form benign (not cancerous) moles. A change in size, shape, or colour of a mole can be a sign of melanoma. Melanoma can be cured if detected early, before spread (metastasis) to other areas of the body. Diagnosis is confirmed with a biopsy of the abnormal skin. Sun exposure can cause skin damage that can lead to melanoma. (12 Dec 1998) |
| malignant lentigo melanoma | <tumour> A melanoma arising from a malignant lentigo. (05 Mar 2000) |
| malignant melanoma | <oncology, tumour> A malignant tumour which arises from the pigment producing cells (melanosomes) of the deeper layers of the skin (or the eye). Melanoma is the leading cause of death attributable to skin lesions. Described as an irregular dark skin lesion that may have areas of varying colour. Often greater than 6 mm in diameter. (27 Sep 1997) |
| malignant melanoma in situ | A melanoma limited to the epidermis and composed of nests of atypical melanocytes and scattered single cells extending into the upper epidermis; local excision is curative although the lesion, if untreated, may soon invade the dermis. Malignant lentigo may be considered a slowly progressive type of malignant melanoma in situ. (05 Mar 2000) |
| malignant melanoma: staging | <radiology> Clark staging: level I: all tumour cells above basement membrane (in situ), level II: tumour extends to papillary dermis, level III: tumour extends to interface between papillary and reticular dermis, level IV: tumour extends between bundles of collagen of reticular dermis, level V: tumour invasion of sucutaneous tissue (87% metastases) Breslow staging: thin: less than 0.75 mm depth of invasion, intermediate: 0.76 - 3.99 mm depth of invasion, thick: greater than 4 mm depth of invasion see: malignant melanoma (12 Dec 1998) |
| desmoplastic malignant melanoma | <tumour> A melanoma with marked fibrosis surrounding atypical spindle-shaped melanocytes in the dermis. (05 Mar 2000) |
| gallium | <chemistry, element> A rare metallic element, found in certain zinc ores. It is white, hard, and malleable, resembling aluminium, and remarcable for its low melting point (86 F, 30C). The element was predicted with most of its properties, under the name ekaluminium, by the Russian chemist Mendelejeff, on the basis of the Periodic law. This prediction was verified in its discovery by the French chemist Lecoq de Boisbaudran by its characteristic spectrum (two violet lines), in an examination of a zinc blende from the Pyrenees. Atomic weight: 69.9 Abbreviation: Ga Origin: NL, fr. L. Gallia France. Source: Websters Dictionary (01 Mar 1998) |
| gallium-67 | A cyclotron-produced radionuclide with a half-life of 3.260 days and major gamma ray emissions of 93, 185, and 300 kiloelectron volts; used in the citrate form as a tumour-and inflammation-localizing radiotracer. (05 Mar 2000) |
| gallium-67 citrate | <radiology> Analogue of ferric iron, decay: by electron capture to ground state of Zn-67, energy levels: 92 KeV (40%); 184 KeV (23%); 296 KeV (21%), physiological half life: 3.3 days (78 hr), biological half life: 2-3 weeks, binding sites: serum: transferrin, haptoglobin, albumin, globulins, tissue: lactoferrin, PMN's (viable and nonviable), lymphocytes, macrophages, bacteria and fungi, tumour cell-associated transferrin receptor see: gallium: indications (12 Dec 1998) |
| gallium-68 | A positron emitter with a radioactive half-life of 1.130 hours. (05 Mar 2000) |
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