| malarial crescent | The male or female gametocyte(s) of Plasmodium falciparum, whose presence in human red blood cells is diagnostic of falciparum malaria. Synonym: crescent, sickle form. Myopic crescent, a white or grayish white crescentic area in the fundus of the eye located on the temporal side of the optic disk; caused by atrophy of the choroid, permitting the sclera to become visible. Synonym: myopic conus. Sublingual crescent, the crescent-shaped area on the floor of the mouth formed by the lingual wall of the mandible and the adjacent part of the floor of the mouth. (05 Mar 2000) |
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| articular crescent | A crescent-shaped intra-articular fibrocartilage found in certain joints. Synonym: meniscus articularis, articular crescent, intra-articular cartilage. (05 Mar 2000) |
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| glomerular crescent | Proliferated epithelial cells partly encircling a renal glomerulus; it occurs in glomerulonephritis. (05 Mar 2000) |
| grey crescent | <biology> A region near the equator of the surface in the fertilized egg of various amphibia, often of greyish colour, that appears to contain special morphogenetic properties. (18 Nov 1997) |
| crescent | 1. Any figure of the shape of the moon in its first quarter. 2. The figure made by the gray columns or cornua on cross-section of the spinal cord. Synonym: malarial crescent. Origin: L. Cresco, pp. Cretus, to grow (05 Mar 2000) |
| crescent cell | <haematology, pathology> An erythrocyte that changes from the normal discoid shape to a sickled shape when the oxygen tension is low. The pesence of these cells indicates that the patient is homozygotes for the allele that codes for haemoglobin S and that the patient has sickle cell anaemia. (18 Nov 1997) |
| crescent cell anaemia | <haematology> Disease common in races of people from areas in which malaria is endemic. The cause is a point mutation in the allele that codes for the beta chain of haemoglobin with a substitution of (valine for glutamic acid at position 6. The defective haemoglobin (HbS) crystallizes readily at low oxygen tension. In consequence, erythrocytes from homozygotes change from the normal discoid shape to a sickled shape when the oxygen tension is low and these sickled cells become trapped in capillaries or damaged in transit, leading to severe anaemia. In heterozygotes, the disadvantages of the abnormal haemoglobin are apparently outweighed by increased resistance to Plasmodium falciparum malaria, probably because parasitised cells tend to sickle and are then removed from circulation. Symptoms include joint pain, acute abdominal pain, and ulcerations of the lower extremities. Origin: Gr. Haima = blood (18 Nov 1997) |
| malarial | Pertaining to or affected with malaria. (05 Mar 2000) |
| malarial cachexia | Malaria that develops after frequently repeated attacks of one of the acute forms, usually falciparum malaria; it is characterised by profound anaemia, enlargement of the spleen, emaciation, mental depression, sallow complexion, oedema of ankles, feeble digestion, and muscular weakness. Synonym: limnaemia, malarial cachexia. (05 Mar 2000) |
| malarial haemoglobinuria | A condition, now uncommon, resulting from Plasmodium falciparum infection (malignant tertian malaria with severe haemolysis); frequently seen in Caucasians after interrupted treatment with quinine. Synonym: blackwater fever, haemoglobinuric fever, West African fever. (05 Mar 2000) |
| malarial knobs | Rounded protrusions of a red blood cell infected with Plasmodium falciparum, responsible for the adhesion of infected red cells to one another and to the endothelium of the blood vessels containing these infected cells; results in capillary blockage responsible for much of the pathology of malignant tertian malaria. (05 Mar 2000) |
| malarial periodicity | A clinical rhythmicity reflected in periodic fevers and chills recurring at approximately 48-hour intervals in tertian malaria (Plasmodium vivax or P. Ovale) or at 72-hour intervals in quartan malaria (Periodicity malariae); the rhythm of tertian or 48-hour cycles is frequently modified in malignant tertian or falciparum malaria (P. Falciparum); associated with release of merozoites from red cells during erythrocytic schizogony, although the controlling mechanism for the synchronous release is unknown. (05 Mar 2000) |
| malarial pigment | A dark brown, granular pigment which rotates the plane of polarised light and has other properties similar to formalin pigment; occurs in parasites, such as Plasmodium malariae, around brain capillaries, and in fixed macrophages of spleen, liver, bone marrow, and lymph nodes. See: malarial pigment stain. (05 Mar 2000) |
| malarial pigment stain | <technique> A stain using phloxine-toluidine blue O sequence; malarial pigment and nuclei are bluish, erythrocytes and cytoplasm are red to orange; found in phagocytic cells of the reticuloendothelial system. (05 Mar 2000) |
| malignant tertian malarial parasite | A species of protozoa that is the causal agent of falciparum malaria (malaria, falciparum). It is most prevalent in the tropics and subtropics. (12 Dec 1998) |
| intermittent malarial fever | See: intermittent malaria. (05 Mar 2000) |
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