| FKBP | FK 506 [macrolide] binding protein |
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| MLS | Macrolide-lincosamide-streptogramin B |
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| MLS | macrolide-lincosamide-streptogramin |
| MLS(B) | macrolide-lincosamide-streptogramin B |
| macrolide glycosyltransferase | <enzyme> From streptomyces lividans; utilises udp-glucose as cofactor; substrates include macrolides with 12-, 14-, 15-, or 16-atom cyclic polyketide lactones; enzyme specific for the 2'-oh group of saccharide moieties attached to c-5 of the 16-atom lactone ring Registry number: EC 2.4.1.- Synonym: macrolide glucosyltransferase (26 Jun 1999) |
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| antibiotics, macrolide | A group of antibiotics containing a macrocyclic lactone ring linked glycosidically to one or more sugar moieties. These antibiotics are produced by certain species of streptomyces. They often inhibit protein synthesis by binding to the 50s subunits of 70s ribosomes. (12 Dec 1998) |
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| macrolide | <pharmacology> A group of antibiotics produced by various strains of Streptomyces that have a complex macrocyclic structure. They inhibit protein synthesis by blocking the 50S ribosomal subunit. Include erythromycin, carbomycin. Used clinically as broad spectrum antibiotics, particularly against gram-positive bacteria. (18 Nov 1997) |
| macrolide 2'-kinase | <enzyme> Inducible intracellular enzyme which inactivates 14-member ring macrolides at the 2'-oh of the d-desosamine moiety; from an erythromycin-resistant strain of E coli; GTP, itp and ATP can also act as donors; mph(2')i is encoded by mpha and mrx, which have been sequenced Registry number: EC 2.7.1.136 Synonym: oleandomycin 2'-phosphotransferase, macrolide 2'-phosphotransferase, macrolide 2'-phosphotransferase I, mph(2')i (26 Jun 1999) |
| alpha-glucan branching glycosyltransferase | 1,4-alpha-d-glucan branching enzyme |
| asparagine-N-glycosyltransferase | <enzyme> Involved in glycoprotein biosynthesis Registry number: EC 2.4.1.- (26 Jun 1999) |
| glycoprotein glycosyltransferase | <enzyme> Enzymes which add monosaccharides from nucleoside mono-or diphosphate monosaccharides onto glycoproteins Registry number: EC 2.4.1.- (26 Jun 1999) |
| glycosyltransferase | <enzyme> Enzymes that catalyze the transfer of glycosyl group to an acceptor. Most often another carbohydrate molecule acts as an acceptor, but inorganic phosphate can also act as an acceptor, such as in the case of phosphorylases. Some of the enzymes in this group also catalyze hydrolysis, which can be regarded as transfer of a glycosyl group from the donor to water. Subclasses include the hexosyltransferases, pentosyltransferases, sialyltransferases, and those transferring other glycosyl groups. Registry number: EC 2.4 Synonym: transglycosylase. (08 Mar 2000) |
| dextrin glycosyltransferase | Dextrin transglycosylase or glycosyltransferase;a 4-glycosyltransferase converting maltodextrins into amylose and glucose by transferring parts of 1,4-glucan chains to new 4-positions on glucose or other 1,4-glucans. Synonym: amylomaltase, D enzyme, dextrin glycosyltransferase, dextrin transglycosylase, disproportionating enzyme. (05 Mar 2000) |
| oligoglucan-branching glycosyltransferase | A glucosyltransferase that transfers an alpha-glucosyl residue in a 1,4-alpha-glucan to the primary hydroxyl group of glucose in a 1,4-alpha-glucan. See: 1,4-alpha-d-glucan branching enzyme. Synonym: oligoglucan-branching glycosyltransferase. (05 Mar 2000) |
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