| mRNA | messenger Ribo-Nucleic Acid |
|---|---|
| ACID | Arithmetic, Coding, Information, and Digit Span; automatic implantable cardioverter defibrillator |
| HCPCS | Health Care Financing Administration common procedural collecting system; Health Care Financing Admi... |
| H-mRNA | H-chain messenger ribonucleic acid |
| mRNA | messenger ribonucleic acid |
| pre-mRNA | Precursor mRNA |
|---|---|
| ODMR | Optical detection of triplet-state magnetic resonance |
| 3'NCR | 3' non-coding region |
| 5' NCR | 5' Non-coding region |
| 5' NC | 5' non-coding |
| coding | Translation of information, e.g., diagnoses, questionnaire responses, into numbered categories for entry into a data processing system. (05 Mar 2000) |
|---|---|
| coding sequence | The portion of DNA that codes for transcription of messenger RNA. See: exon. (05 Mar 2000) |
| coding strand | The strand of duplex DNA that has the same sequence as the mRNA (except that mRNA contains ribonucleotides instead of deoxyribonucleotides). Synonym: sense strand. (05 Mar 2000) |
| nonsense triplet | A trinucleotide (codon) in which a base change to a termination codon results in premature termination of the growing polypeptide chain and, consequently, incomplete protein molecules, a termination codon. (05 Mar 2000) |
| triplet | <microscopy> A combination of three simple lenses cemented together. Two positive lenses with a negative lens between them can produce a well-corrected system. (05 Aug 1998) |
| triplet state | A second excited state of a molecule (e.g., chlorophyll) produced by absorption of light to produce the singlet state, then loss of some energy (fluorescence) to arrive at the longer-lived triplet state The molecule may remain sufficiently long in the triplet state for a second activating light quantum to be effective in producing a "second triplet" state, obviously at still a higher level of excitation, hence reactivity. Alternatively, it may lose the triplet state energy directly and return to the ground state. (05 Mar 2000) |
| alternative mRNA splicing | Splicing different exons in or out of messenger RNA to form different mRNA transcripts. (09 Oct 1997) |
| capping of mRNA | The process of adding a guanosine nucleotide to the 5'-end (the beginning) of an eukaryotic mRNA, then methylating (adding a -CH3 to) the guanosine. (09 Oct 1997) |
| maternal mRNA | <molecular biology> Messenger RNA found in oocytes and early embryos that is derived from the maternal genome during oogenesis. See: masked messenger RNA. (18 Nov 1997) |
| mRNA | <molecular biology> Single stranded RNA molecule that specifies the amino acid sequence of one or more polypeptide chains. This information is translated during protein synthesis when ribosomes bind to the mRNA. In prokaryotes, mRNA is normally formed by splicing a large primary transcript from a DNA sequence and protein synthesis starts while the mRNA is still being synthesised. Prokaryote mRNAs are usually very short lived (average t 1/2 is 5mins.). In contrast, in eukaryotes the primary transcripts (HnRNA) are synthesised in the nucleus and they are extensively processed to give the mRNA that is exported to the cytoplasm where protein synthesis takes place. This processing includes the addition of a 5' 5' linked 7 methyl guanylate cap at the 5' end and a sequence of adenylate groups at the 3' end, the poly A tail, as well as the removal of any introns and the splicing together of exons, only 10% of HnRNA leaves the nucleus. Eukaryote mRNAs are comparatively long lived with a half life ranging from 30minutes to 24 hours. (27 Jun 1999) |
| mRNA (2'-O-methyladenosine-N6-)-methyltransferase | <enzyme> Involved in capping mRNA Registry number: EC 2.1.1.62 Synonym: mRNA n(6)-adenosine methyltransferase, mra methyltransferase, RNA(2'-o-methyladenosine-n(6)-)methyltransferase (26 Jun 1999) |
| mRNA(adenine-N6)-methyltransferase | <enzyme> Methylates mRNA at internal adenosine within the consensus sequence puac(a/c/u) Registry number: EC 2.1.1.- Synonym: mRNA-a-n6-methyltransferase, mRNA(adenine-n6)-methylase (26 Jun 1999) |
| mRNA (guanine(N7))-methyltransferase | <enzyme> Catalyses s-adenosyl-l-methionine and g(5')pppr-RNA to yield s-adenosyl-l-homocysteine and m(7)g(5')pppr-RNA; mRNA containing an n(7)-methylguanine cap Registry number: EC 2.1.1.56 Synonym: mRNA (guanine-7-)methyltransferase, mRNA(guanine-7-)methyltransferase, RNA (guanine-7) methyltransferase, abd1 gene product (26 Jun 1999) |
| mRNA guanylyltransferase | <enzyme> Catalyses transfer of GMP residue from GTP to 5' end of RNA to form cap structure identified as g(5')pppn; can also modify synthetic poly(a) and poly(g) to form m7g(5')pppan and m7g(5')pppgn; see also capping enzyme, vaccinia virus Registry number: EC 2.7.7.50 Synonym: RNA guanylyltransferase, m-RNA guanylyltransferase, GTP mRNA guanylyltransferase, mRNA capping enzyme, mRNA 5'-guanylyltransferase, cgt1 gene product, ceg1 gene product (26 Jun 1999) |
| mRNA maturase | <enzyme> Also potent endonuclease involved in recombination Registry number: EC 2.7.7.- Synonym: RNA, mitochondrial maturase, RNA maturase (26 Jun 1999) |
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