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| mRNA | messenger Ribo-Nucleic Acid |
|---|---|
| H-mRNA | H-chain messenger ribonucleic acid |
| mRNA | messenger ribonucleic acid |
| pre-mRNA | precursor messenger ribonucleic acid |
| TC | target cell; taurocholate; temperature compensation; teratocarcinoma; tertiary cleavage; tetracyclin... |
| CPSF | Cleavage and polyadenylation specificity factor |
|---|---|
| pre-mRNA | Precursor mRNA |
| CPE | Cytoplasmic polyadenylation elements |
| GDF | Growth and differentiation factors |
| IGFBPs | Insulin-like growth factors and their binding proteins |
unequal cleavage
acute angle
| polyadenylation | 1. The process of formation of poly(adenylic acid). 2. The covalent modification of a macromolecule (e.g., mRNA) by the formation of a polyadenylyl moiety covalent linked to the macromolecule. (05 Mar 2000) |
|---|---|
| immunologic and biological factors | A collective grouping for biologically active substances that play a role in the functioning of the immune system and those that show biological or physiological activity. (12 Dec 1998) |
| alternative mRNA splicing | Splicing different exons in or out of messenger RNA to form different mRNA transcripts. (09 Oct 1997) |
| capping of mRNA | The process of adding a guanosine nucleotide to the 5'-end (the beginning) of an eukaryotic mRNA, then methylating (adding a -CH3 to) the guanosine. (09 Oct 1997) |
| maternal mRNA | <molecular biology> Messenger RNA found in oocytes and early embryos that is derived from the maternal genome during oogenesis. See: masked messenger RNA. (18 Nov 1997) |
| mRNA | <molecular biology> Single stranded RNA molecule that specifies the amino acid sequence of one or more polypeptide chains. This information is translated during protein synthesis when ribosomes bind to the mRNA. In prokaryotes, mRNA is normally formed by splicing a large primary transcript from a DNA sequence and protein synthesis starts while the mRNA is still being synthesised. Prokaryote mRNAs are usually very short lived (average t 1/2 is 5mins.). In contrast, in eukaryotes the primary transcripts (HnRNA) are synthesised in the nucleus and they are extensively processed to give the mRNA that is exported to the cytoplasm where protein synthesis takes place. This processing includes the addition of a 5' 5' linked 7 methyl guanylate cap at the 5' end and a sequence of adenylate groups at the 3' end, the poly A tail, as well as the removal of any introns and the splicing together of exons, only 10% of HnRNA leaves the nucleus. Eukaryote mRNAs are comparatively long lived with a half life ranging from 30minutes to 24 hours. (27 Jun 1999) |
| mRNA (2'-O-methyladenosine-N6-)-methyltransferase | <enzyme> Involved in capping mRNA Registry number: EC 2.1.1.62 Synonym: mRNA n(6)-adenosine methyltransferase, mra methyltransferase, RNA(2'-o-methyladenosine-n(6)-)methyltransferase (26 Jun 1999) |
| mRNA(adenine-N6)-methyltransferase | <enzyme> Methylates mRNA at internal adenosine within the consensus sequence puac(a/c/u) Registry number: EC 2.1.1.- Synonym: mRNA-a-n6-methyltransferase, mRNA(adenine-n6)-methylase (26 Jun 1999) |
| mRNA (guanine(N7))-methyltransferase | <enzyme> Catalyses s-adenosyl-l-methionine and g(5')pppr-RNA to yield s-adenosyl-l-homocysteine and m(7)g(5')pppr-RNA; mRNA containing an n(7)-methylguanine cap Registry number: EC 2.1.1.56 Synonym: mRNA (guanine-7-)methyltransferase, mRNA(guanine-7-)methyltransferase, RNA (guanine-7) methyltransferase, abd1 gene product (26 Jun 1999) |
| mRNA guanylyltransferase | <enzyme> Catalyses transfer of GMP residue from GTP to 5' end of RNA to form cap structure identified as g(5')pppn; can also modify synthetic poly(a) and poly(g) to form m7g(5')pppan and m7g(5')pppgn; see also capping enzyme, vaccinia virus Registry number: EC 2.7.7.50 Synonym: RNA guanylyltransferase, m-RNA guanylyltransferase, GTP mRNA guanylyltransferase, mRNA capping enzyme, mRNA 5'-guanylyltransferase, cgt1 gene product, ceg1 gene product (26 Jun 1999) |
| mRNA maturase | <enzyme> Also potent endonuclease involved in recombination Registry number: EC 2.7.7.- Synonym: RNA, mitochondrial maturase, RNA maturase (26 Jun 1999) |
| mRNA (nucleoside-O(2'))-methyltransferase | <enzyme> Catalyses the reaction of s-adenosyl-l-methionine and m(7)g(5')pppr-RNA to yield s-adenosyl-l-homocysteine and m(7)g(5')ppprm-RNA; mRNA containing an o(2')-methylpurine cap Registry number: EC 2.1.1.57 (26 Jun 1999) |
| polycistronic mRNA | <molecular biology> A single mRNA molecule that is the product of the transcription of several tandemly arranged genes, typically the mRNA transcribed from an operon. (18 Nov 1997) |
| 6-methyladenine mRNA methyltransferase | <enzyme> Forms internal n6-methyladenine residues Registry number: EC 2.1.1.- Synonym: m6a mRNA methyltransferase (26 Jun 1999) |
| abnormal cleavage of cardiac valve | Congenital malformation of a valve leaflet with a defect extending from the free margin. (05 Mar 2000) |
Synonyms : Cleavage and Polyadenylation Factor, Polyadenylation Factor, Pre-mRNA Polyadenylation Factor, Polyadenylation Factor, Pre-mRNA, Pre mRNA Polyadenylation Factor
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