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  • Lysosomal membrane
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  • Infectious Diseases Society of America
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  • allergic diseases
    ¾Ë·¹¸£±â(¼º) Áúȯ
  • allergic diseases
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LAL left axillary line; Limulus amebocyte lysate; low air loss; lysosomal acid lipase
ICD I-cell disease; immune complex disease; implantable cardioverter defibrillator; impulse-control diso...
AJKD American Journal of Kidney Diseases
ICD   1) International (statistical) Classification of Diseases, (injuries & causes of death)<...
STDs Sexual Transmitted Diseases [Chap 88, HP 534-43]
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LSD Lysosomal storage diseases
LAL Lysosomal acid lipase
LAP Lysosomal acid phosphatase
ML mitochondrial lysosomal
AID Auto-immune diseases
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lysosomal diseases Diseases (also called storage diseases) in which a deficiency of a particular lysosomal enzyme leads to accumulation of the undigested substrate for that enzyme within cells. Not immediately fatal, but within a few years lead to serious neurological and skeletal disorders and eventually to death.
See: the following conditions: Hurler sundrome, Hunter syndrome, San Fillipo, Gaucher's disease, Niemann-Pick, Pompe's disease, Tay Sachs disease.
(18 Nov 1997)
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lysosomal storage diseases Inborn errors of metabolism characterised by defects in specific lysosomal hydrolases and resulting in intracellular accumulation of unmetabolised substrates.
(12 Dec 1998)
inborn lysosomal disease Inherited disorder of one or more degradative enzymes normally located in lysosomes leading to accumulation (storage) of abnormal quantities of a substance, such as a glycosaminoglycan as in Hurler's syndrome or a lipopolysaccharide as in Gaucher's disease.
(05 Mar 2000)
UDP-N-acetylglucosamine-lysosomal-enzyme-N-acetylglucosaminephosphotransferase <enzyme> Fibroblasts from patients with i-cell (mucolipidosis II) and pseudo-hurler polydystrophy (mucolipidosis III) are deficient in above enzyme; for n-acetylglucosamine transferred to dolichyl phosphate see EC 2.7.8.15
Registry number: EC 2.7.8.17
Synonym: udpgnac gp gnac phosphotransferase, udpgnac phosphotransferase, uridine 5'-diphosphate-n-acetylglucosamine glycoprotein n-acetylglucosaminylphosphotransferase, n-acetylglucosamine-1-phosphotransferase, n-agapt, udp-n-acetylglucosamine-lysosomal glycoprotein n-acetylglucosaminylphosphotransferase, udp-acetylglucosamine-glycoprotein n-acetylglucosamine-1-phosphotransferase
(26 Jun 1999)
UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosaminyl-1-phosphotransferase <enzyme> An enzyme that participates in the posttranslational modification of a number of lysosomal proteins; a deficiency or defect in this enzyme results in two forms of mucolipidoses, I-cell disease, and pseudo-Hurler polydystrophy.
(05 Mar 2000)
lysosomal disease A disease due to inadequate functioning of a lysosomal enzyme; most such disease's are associated with a storage disease.
(05 Mar 2000)
lysosomal enzyme <biochemistry> A range of degradative enzymes, most of which operate best at acid pH. The best known marker enzymes are acid phosphatase and glucuronidase, but many others are known.
(18 Nov 1997)
acoustic nerve diseases Diseases of the eighth cranial nerve. These include vestibular neuronitis, cochlear neuritis and acoustic neuroma.
(12 Dec 1998)
adaptation diseases Disease's falling theoretically into Selye's concept of the general-adaptation syndrome.
(05 Mar 2000)
adnexal diseases Diseases of the uterine appendages: the ovaries, uterine tubes, and ligaments of the uterus.
(12 Dec 1998)
agricultural workers' diseases Diseases in persons engaged in cultivating and tilling soil, growing plants, harvesting crops, raising livestock, or otherwise engaged in husbandry and farming. The diseases are not restricted to farmers in the sense of those who perform conventional farm chores: the heading applies also to those engaged in the individual activities named above, as in those only gathering harvest or in those only dusting crops.
(12 Dec 1998)
ape diseases Diseases of apes (pongidae). This term includes diseases of chimpanzees, gorillas, and orangutans.
(12 Dec 1998)
arterial occlusive diseases Diseases in which arterial vessels are partially or completely obstructed or in which the blood flow through the vessels is impeded.
(12 Dec 1998)
auditory diseases, central Diseases of the auditory pathways from the bulbar cochlear nuclei to the auditory cortex in the temporal lobe. Structures involved include the medial and lateral lemnisci, inferior colliculus, and the medial geniculate nucleus.
(12 Dec 1998)
autoimmune diseases Are illnesses which occur when the body tissues are attacked by its own immune system. The immune system is a complex organisation within the body that is designed normally to seek and destroy invaders of the body, particularly infections. Patients with these diseases have unusual antibodies in their blood that target their own body tissues.
(12 Dec 1998)
autonomic nervous system diseases Diseases that have their major effects on the autonomic nervous system. The autonomic nervous system may be seriously affected in many other disorders including other peripheral nervous system diseases, infectious diseases (e.g., tetanus, diphtheria), immunologic diseases (e.g., acquired immunodeficiency syndrome), and systemic disorders (e.g., diabetic neuropathy, amyloid neuropathy, thyroid diseases). Disorders of central autonomic control also contribute substantially to a wide variety of problems (e.g., eating disorders, panic disorder, water-electrolyte imbalance, cardiovascular diseases).
(12 Dec 1998)
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