| 영문 | systemic lupus erythematosus | 한글 | 전신홍반루푸스 |
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| 설명 | 전신 자가면역병의 대표적 병이다. 여성에게 압도적으로 많고, 10~39세까지가 70%를 차지한다. 원인은 잘 모르나 자가면역 조절기능에 장애가 있는 것으로 생각된다. 유전요인, 호르몬의 영향, 환경요소가 종합적으로 보조 T세포와 B세포를 활성화시켜서 여러 가지 자가항체들, 즉 천연 DNA, 이중가닥 DNA, 외가닥 DNA, RNA, 핵단백질 등과 같은 핵 항원에 대한 항체, 비핵항원에 대한 여러 가지 항체가 쏟아져 나온다. 이 중 이중가닥 DNA를 포함한 순환면역복합체가 콩팥에 침착하여 손상을 일으키는데 관여한다. DNA와 여러 가지 세포성분에 대한 자가면역질환으로 전콩팥기를 침범하여 염증을 일으킨다. 여러 자가항원에 대한 면역반응에 의한 항체의존성 면역반응과 면역복합체 반응으로 토리콩팥염, 혈관염, 관절염 및 빈혈을 동반한다. |
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| 영문 | poststreptococcal glomerulonephritis | 한글 | 사슬알균감염후토리콩팥염, 연쇄구균감염후사구체신염 |
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| 설명 | 점차 감소추세이기는 하나 어린이 콩팥병으로 아주 흔하다. 사슬알균 감염, 특히 상기도나 피부 감염 후 1주 내지 2주 이내에 급성콩팥염증후군이 갑자기 발현되는 특징을 보인다. 성인에서도 발생할 수 있으나 비교적 드물고 그 임상소견이 다소 다를 수 있다. 발생메커니즘은 면역으로 해석하고 있다. |
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| 영문 | glomerulonephritis | 한글 | 토리콩팥염, 사구체신염 |
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| 설명 | 토리콩팥염이란 이 토리의 염증을 주로 하는 콩팥병을 말한다. 이 토리콩팥염의 진단은 하지만 현미경적 관찰로 토리의 염증을 보고 진단하는 것이 아니라 임상증세로 진단하는 것이므로 다분히 임상적인 진단명이다. 즉 심하게 말하면 실제로 토리의 염증이 없는 경우에도 임상적 진단 기준에만 합당한 경우에는 토리콩팥염으로 진단이 내려질 수가 있다. 토리콩팥염은 급성과 만성의 두 가지로 나눌 수가 있다. 1.급성토리콩팥염－갑작스럽게 발생하는 혈뇨, 단백뇨, 그리고 콩팥의 기능부전으로 인해서 수분이나 전해질의 체내 축적, 불순물의 체내축적이 있는 병을 말한다. 이 급성 토리콩팥염을 일으키는 원인으로는 여러가지가 있지만 대표적인 것으로는 대부분 감염(사슬알균, 포도알균, 폐렴알균, 여러 바이러스 등)후에 초래되는 감염후 토리콩팥염이 있다. 여러 감염이 급성 토리콩팥염을 일으키나 특히 사슬알의 감염이 가장 전형적인 예라고 할 수 있다. 2.만성토리콩팥염-지속적인 요검사상의 이상, 즉 단백뇨, 혈뇨와 신장의 기능이 서서히 없어지는 질환군이다. 흔히 말기콩팥이라 부르며 거의 모든 콩팥의 병이 이 만성 토리콩팥염으로 진행된다. |
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| MCGN | mesangiocapillary glomerulonephritis; minimal change glomerulonephritis; mixed cryoglobulinemia with... |
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| DLE | delayed light emission; dialyzable leukocyte extract; discoid lupus erythematosus; disseminated lupu... |
| DLE | Discoid Lupus Erythematosus |
| LE | Lupus Erythematosus; 홍반성 루푸스(낭창) |
| SCLE | Subacute Cutaneous Lupus Erythematosus |
| BILAG | British Isles Lupus Assessment Group |
|---|---|
| DPLN | Diffuse proliferative lupus nephritis |
| DLE | Discoid Lupus Erythematosus |
| LAC | Lupus AntiCoagulant |
| LA | lupus anticoagulans |
| lupus glomerulonephritis-pathology | Patient survival and preservation of renal function are predictable from renal pathology as demonstrated by biopsy and defined by the histological classification of the International Study of Kidney Disease in Children/World Health Organization (ISKDC/WHO). Semi-quantitative indices of nephron loss (chronicity index) and activity of acute potentially reversible inflammation (activity index) are not predictive of individual outcome, renal failure or death in patients with aggressively treated SLE GN. (05 Mar 2000) |
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| acute crescentic glomerulonephritis | <nephrology> A relatively uncommon (affecting 1 out of 10,000 people) form of acute glomerulonephritis that results in damage within the glomerulus of the kidney. There is rapid loss of kidney function with the formation of crescents on microscopic analysis (kidney biopsy). This disorder may result in acute glomerulonephritis or nephrotic syndrome, but ultimately results in renal failure and end-stage renal disease. Symptoms include smoky coloured urine (pyuria), decreased urine output, swelling and hypertension. Any conditions which can cause a vasculitis increase the risk of this disorder. Some examples include lupus, Goodpasture's syndrome, Henoch-Schonlein purpura, IgA nephropathy, membranoproliferative glomerulonephritis, anti-glomerular basement membrane antibody disease, history for malignant tumours and exposure to hydrocarbon solvents. (27 Sep 1997) |
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| acute glomerulonephritis | <nephrology> A disease of the kidneys that results in inflammation of the glomerulus (the portion of the kidney that filters the blood). Conditions which may cause glomerulonephritis include post-streptococcal disease (strep throat), lupus, syphilis, bacterial endocarditis, membranoproliferative glomerulonephritis, sepsis, vasculitis, Goodpasture's syndrome, typhoid fever, Henoch-Schonlein purpura, hepatitis or a viral infection (for example mumps, measles, mononucleosis). (27 Sep 1997) |
| acute haemorrhagic glomerulonephritis | <nephrology> A disease of the kidneys that results in inflammation of the glomerulus (the portion of the kidney that filters the blood). Conditions which may cause glomerulonephritis include post-streptococcal disease (strep throat), lupus, syphilis, bacterial endocarditis, membranoproliferative glomerulonephritis, sepsis, vasculitis, Goodpasture's syndrome, typhoid fever, Henoch-Schonlein purpura, hepatitis or a viral infection (for example mumps, measles, mononucleosis). (27 Sep 1997) |
| acute post-streptococcal glomerulonephritis | <nephrology> A disease of the kidneys that results in inflammation of the glomerulus (the portion of the kidney that filters the blood). Conditions which may cause glomerulonephritis include post-streptococcal disease (strep throat), lupus, syphilis, bacterial endocarditis, membranoproliferative glomerulonephritis, sepsis, vasculitis, Goodpasture's syndrome, typhoid fever, Henoch-Schonlein purpura, hepatitis or a viral infection (for example mumps, measles, mononucleosis). (27 Sep 1997) |
| anti-basement membrane glomerulonephritis | Glomerulonephritis resulting from anti-basement membrane antibodies, characterised by smooth linear deposits of IgG and C3 along glomerular capillary walls; includes rapidly progressive glomerulonephritis and glomerulonephritis in Goodpasture's syndrome. (05 Mar 2000) |
| Berger's focal glomerulonephritis | Glomerulonephritis affecting a small proportion of renal glomeruli which commonly presents with haematuria and may be associated with acute upper respiratory infection in young males, not usually due to streptococci; associated with IgA deposits in the glomerular mesangium and may also be associated with systemic disease, as in Henoch-Schonlein purpura. Synonym: Berger's disease, Berger's focal glomerulonephritis, focal nephritis, IgA nephropathy. (05 Mar 2000) |
| rapidly progressive glomerulonephritis | <nephrology> A relatively uncommon (affecting 1 out of 10,000 people) form of acute glomerulonephritis that results in damage within the glomerulus of the kidney. There is rapid loss of kidney function with the formation of crescents on microscopic analysis (kidney biopsy). This disorder may result in acute glomerulonephritis or nephrotic syndrome, but ultimately results in renal failure and end-stage renal disease. Symptoms include smoky coloured urine (pyuria), decreased urine output, swelling and hypertension. Any conditions which can cause a vasculitis increase the risk of this disorder. Some examples include lupus, Goodpasture's syndrome, Henoch-Schonlein purpura, IgA nephropathy, membranoproliferative glomerulonephritis, anti-glomerular basement membrane antibody disease, history for malignant tumours and exposure to hydrocarbon solvents. (27 Sep 1997) |
| glomerulonephritis | <nephrology> A variety of nephritis characterised by inflammation of the capillary loops in the glomeruli of the kidney. It occurs in acute, subacute and chronic forms and may be secondary to haemolytic streptococcal infection. Evidence also supports possible immune or autoimmune mechanisms. (18 Nov 1997) |
| glomerulonephritis, IgA | Chronic form of glomerulonephritis characterised by recurring haematuria with only slight proteinuria and by deposits of IgA immunoglobulin in the mesangial areas of the renal glomeruli. It usually occurs in young males. (12 Dec 1998) |
| glomerulonephritis, membranoproliferative | Chronic glomerulonephritis characterised histologically by proliferation of mesangial cells, increase in the mesangial matrix, and a thickening of the glomerular capillary walls. The wall thickening is sometimes said to be a result of the interposition of mesangial cytoplasm or matrix between the basement membrane and the endothelium of the capillary wall. It is often divided into types I and II, and sometimes III. Pathogenesis is not well understood, but some types are thought to involve the immune system, with the complement system, in particular, being implicated. (12 Dec 1998) |
| glomerulonephritis, membranous | A disease of the glomerulus manifested clinically by proteinuria, and sometimes by other features of the nephrotic syndrome. It is histologically characterised by deposits in the glomerular capillary wall between the epithelial cell and the basement membrane and a thickening of the membrane. Also characteristic are outward projections of the membrane between the epithelial deposits in the form of "spikes". There is some agreement that the deposits are antigen-antibody complexes. (12 Dec 1998) |
| membranoproliferative glomerulonephritis | <pathology> A kidney disorder which results in kidney dysfunction. Inflammation of the glomeruli result from an abnormal immune response and the deposition of antibodies within the kidney (glomerulus) ultrastructure. Membranoproliferative glomerulonephritis has been divided into two different types in the basis of where the antibodies are deposited in the glomerulus. MPGN type I, the more common type, deposits antibodies in the subendothelial layer of the basement membrane, whereas type II deposits antibodies in the bottom layer of the basement membrane. Symptoms include cloudy urine (pyuria), decreased urine output, swelling and hypertension. This disorder often results in end-stage renal disease. Acronym: MPGN (26 Mar 1998) |
| membranous glomerulonephritis | <pathology> A kidney disease that occurs due to inflammation of the kidney glomerulus and its basement membrane. The exact cause is unknown but it appears to be related to the deposition of immune complexes in the basement membrane leading to thickening of the capillary walls. This disorder is a common cause of nephrotic syndrome an is usually how the disease manifests. Risk factors include primary renal disease, malaria, hepatitis B, lupus, syphilis, cancers and non-Hodgkin's lymphomas. Risks also include exposure to some medications such as gold compounds and penicillamine. Mercury, trimethadione and some skin-lightening creams have also been implicated. Treatment includes systemic corticosteroids and immunosuppressive agents. (26 Mar 1998) |
| mesangial proliferative glomerulonephritis | <nephrology, pathology> Inflammation of the kidney glomerulus (blood filtering portion of the kidney) due to the abnormal deposition of IgM antibody in the mesangium layer of the glomerular capillary. A form of glomerulonephritis that appears to be caused by an abnormal immune response. This disorder generally manifests as nephrotic syndrome. Symptoms include swelling, dark urine, weight gain, hypertension, anorexia and bloody urine. Acronym: MPGN (05 Jan 1998) |
| mesangiocapillary glomerulonephritis | <nephrology, pathology> A kidney disorder which results in kidney dysfunction. Inflammation of the glomeruli result from an abnormal immune response and the deposition of antibodies within the kidney (glomerulus) ultrastructure. Membranoproliferative glomerulonephritis has been divided into two different types in the basis of where the antibodies are deposited in the glomerulus. MPGN type I, the more common type, deposits antibodies in the subendothelial layer of the basement membrane, whereas type II deposits antibodies in the bottom layer of the basement membrane. Symptoms include cloudy urine (pyuria), decreased urine output, swelling and hypertension. This disorder often results in end-stage renal disease. (27 Sep 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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