| FLAP | 5-lipoxygenase activating protein |
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| LOG | lipoxygenase |
| 12-LOX | 12 lipoxygenase |
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| 12-LO | 12-Lipoxygenase |
| LO | 12-lipoxygenase |
| LOX | 12-lipoxygenase |
| 15-LO | 15 lipoxygenase |
| lipoxygenase | <enzyme> Enzyme that catalyses the oxidative conversion of arachidonic acid to the hydroxyeicosenoic acid (HETE) structure in the synthesis of leucotrienes. (18 Nov 1997) |
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| lipoxygenase inhibitors | Compounds or agents that combine with lipoxygenase and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of the eicosanoid products hydroxyeicosatetraenoic acid and various leukotrienes. (12 Dec 1998) |
| arachidonate 12-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-hpete) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-hete). The 12-hydroperoxides are preferentially formed in platelets. Chemical name: Arachidonate:oxygen 12-oxidoreductase Registry number: EC 1.13.11.31 (12 Dec 1998) |
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| arachidonate 15-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-hpete) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-hete). The 15-hydroperoxides are preferentially formed in neutrophils and lymphocytes. Chemical name: Arachidonate:oxygen 15-oxidoreductase Registry number: EC 1.13.11.33 (12 Dec 1998) |
| arachidonate 5-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-hpete) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-hete). The 5-hydroperoxides are preferentially formed in leukocytes. Chemical name: Arachidonate:oxygen 5-oxidoreductase Registry number: EC 1.13.11.34 (12 Dec 1998) |
| arachidonate 8-lipoxygenase | <enzyme> From sea whip coral plexaura homomalla; catalyses the conversion of arachidonic acid to a cyclised prostanoid with a pga ring and the same side chains as the parent arachidonate Registry number: EC 1.13.11.40 Synonym: 8(r)-lipoxygenase, 8-lipoxygenase (26 Jun 1999) |
| 11-lipoxygenase | <enzyme> Sea urchin egg enzyme converts arachidonic acid to 11(r)-hydroperoxyeicosapentaenoic acid Registry number: EC 1.13.11.- Synonym: (11r)-lipoxygenase (26 Jun 1999) |
Synonyms : Linoleate-Oxygen Oxidoreductase, Lipoxygenase-1, Lipoxygenase-2, Lipoxygenases, Linoleate Oxygen Oxidoreductase, Lipoxygenase 1, Lipoxygenase 2, Oxidoreductase, Linoleate-Oxygen
Synonyms : Inhibitors, Lipoxygenase
| lipoxygenase |
Die Lipoxygenase ist ein Enzym, das bestimmte biochemische Abl?fe steuert, es katalysiert stereospezifisch den ersten Schritt der Oxidation von Arachidons?re zu den biochemisch ??rst wirksamen Leukotrienen. Dieses Enzym ist damit an Entz?dungsreaktionen undso z. B. auch an Rheuma beteiligt. Viele entz?dungshemmende Medikamente (z.B. Diclofenac) wirken daher so, dass sie in geeigneter Weise in den Lipoxygenase-Stoffwechsel eingreifen. ...
Ãâó: de.wikipedia.org/wiki/Lipoxygenase
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| lipoxygenase p. |
a pathway for the formation of leukotrienes and hydroxyeicosatetraenoic acids from arachidonic acid. It is initiated by oxidation of arachidonic acid by arachidonate lipoxygenases, and the reactions occur in the cytosol of leukocytes, mast cells, platelets, and lung tissue cells. See illustration. Click here to view image■Lipoxygenase pathway of leukotriene and hydroxyeicosatetraenoic acid synthesis. HPETE, hydroperoxyeicosatetraenoic acid; HETE, hydroxyeicosatetraenoic acid; LT, leukotriene.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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