| ¿µ¹® | pH, hydrogen ion concentration | ÇÑ±Û | ¼ö¼ÒÀ̿³óµµÁö¼ö |
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| ¿µ¹® | ion | ÇÑ±Û | À̿ |
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| ¼³¸í | ºÐÀÚ¸¦ Àü±âºÐÇØÇÒ ¶§ ºÐ¸®µÇ´Â, Àü±â¸¦ ¶í ¹Ì¸³Àڷμ ¾çÀü±â¸¦ ¶í ¾çÀ̿°ú À½Àü±â¸¦ ¶í À½ÀÌ¿ÂÀÌ ÀÖ´Ù. |
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| CNGC | cyclic nucleotide gated channel |
|---|---|
| g-ion | gram-ion |
| ISS | idiopathic short stature; injury severity score; International Society of Surgery; ion-scattering sp... |
| CLD | chloride diarrhea; chronic liver disease; chronic lung disease; congenital limb deficiency; crystal ... |
| MLC | minimum lethal concentration; mixed leukocyte culture; mixed ligand chelate; mixed lymphocyte concen... |
| VGCC | Voltage gated Ca(2+) channel |
|---|---|
| VGCC | voltage gated calcium channel |
| VGSC | voltage-gated sodium channel |
| KATP channel | ATP sensitive potassium channel |
| BK channel | K channel |
channel-shoulder-pin attachment
| ligand gated ion channel | A transmembrane ion channel whose permeability is increased by the binding of a specific ligand, typically a neurotransmitter at a chemical synapse. The permeability change is often drastic, such channels let through effectively no ions when shut, but allow passage at up to 10exp7 ions sexp 1 when a ligand is bound. Recently, the receptors for both acetylcholine and GABA have been found to share considerable sequence homology, implying that there may be a family of structurally related ligand gated ion channels. (18 Nov 1997) |
|---|
| ligand-gated channel | A class of ion channel's whose ionic permeability is regulated by cell membrane receptors that respond to specific extracellular chemical signals. (05 Mar 2000) |
|---|---|
| gated ion channel | <physiology> Transmembrane proteins of excitable cells, that allow a flux of ions to pass only under defined circumstances. Channels may be either voltage gated, such as the sodium channel of neurons or ligand gated such as the acetylcholine receptor of cholinergic synapses. Channels tend to be relatively ion specific and allow fluxes of typically 1000 ions to pass in around 1ms, they are thus much faster at moving ions across a membrane than transport ATPases. (05 May 1997) |
| voltage gated ion channel | <physiology> A transmembrane ion channel whose permeability to ions is extremely sensitive to the transmembrane potential difference. These channels are essential for neuronal signal transmission and for intracellular signal transduction. See: sodium channel. (18 Nov 1997) |
| voltage-gated channel | A class of ion channel's that open and close in response to change in the electrical potential across the plasma membrane of the cell; voltage-gated Na+ c.'s are important for conducting action potential along nerve cell processes. (05 Mar 2000) |
| ion channel | <cell biology> A transmembrane pore that presents a hydrophilic channel for ions to cross a lipid bilayer down their electrochemical gradients. Some degree of ion specificity is usually observed and typically a million ions per second may flow. Channels may be permanently open, like the potassium leak channel or they may be voltage gated, like the sodium channel or ligand gated like the acetylcholine receptor. (27 Oct 1998) |
| ion channel gating | The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability. (12 Dec 1998) |
| gated blood pool imaging | Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at specific times in the cycle, using an electrocardiographic synchroniser or gating device. Analysis of right ventricular function is difficult with this technique; that is best evaluated by first-pass ventriculography (ventriculography, first-pass). (12 Dec 1998) |
| gated radionuclide angiocardiography | Radionuclide angiocardiography using cardiac gating to combine images from several cardiac cycles to improve the quality of the images of separate phases (e.g., systole and diastole). (05 Mar 2000) |
| ambident ligand | <chemistry> A ligand that can donate electrons through two or more atoms on their molecule. (05 Feb 1998) |
| cyanocobalamin beta-ligand transferase | <enzyme> Cytosolic enzyme utilizing fad, NADPH and reduced glutathione; forms glutathionylcobalamin from cyanocobalamin Registry number: EC 2.5.1.- Synonym: ccbl transferase (26 Jun 1999) |
| ELAM-1 ligand fucosyltransferase | <enzyme> Directs the expression of an elam-1 ligand; an alpha(1,3) fucosyltransferase Registry number: EC 2.4.1.- Synonym: elft protein, elft gene product (26 Jun 1999) |
| ligand | <chemistry, immunology> Any molecule that binds to another, in normal usage a soluble molecule such as a hormone or neurotransmitter, that binds to a receptor. The decision as to which is the ligand and which the receptor is often a little arbitrary when the broader sense of receptor is used (where there is no implication of transduction of signal). In these cases it is probably a good rule to consider the ligand to be the smaller of the two thus in a lectin sugar interaction, the sugar would be the ligand (even though it is attached to a much larger molecule, recognition is of the saccharide). (18 Nov 1997) |
| ligand binding site | The site on a protein's surface that binds a ligand; equivalent to the active site if the ligand is the substrate of an enzyme. (05 Mar 2000) |
| ligand induced endocytosis | The formation of coated pits and then coated vesicles as a consequence of the interaction of ligand with receptors, which then interact with clathrin and associated proteins (coatomers) on the cytoplasmic face of the plasma membrane and come together to form a pit. Not all coated vesicle uptake of receptors requires receptor occupancy. (18 Nov 1997) |
| calcium channel | <physiology> A membrane channel that is specific for calcium. It is a voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorised as l, t, n, or p types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. (12 May 2002) |
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