| CLD | chloride diarrhea; chronic liver disease; chronic lung disease; congenital limb deficiency; crystal ... |
|---|---|
| MLC | minimum lethal concentration; mixed leukocyte culture; mixed ligand chelate; mixed lymphocyte concen... |
| MLCT | metal-to-ligand charge transfer |
| APO2L | AP02 ligand |
|---|---|
| CD30L | CD30 ligand |
| CD40L | CD40 Ligand |
| CD40L | CD40-CD40 ligand |
| CD95L | CD95 ligand |
| ligand | <chemistry, immunology> Any molecule that binds to another, in normal usage a soluble molecule such as a hormone or neurotransmitter, that binds to a receptor. The decision as to which is the ligand and which the receptor is often a little arbitrary when the broader sense of receptor is used (where there is no implication of transduction of signal). In these cases it is probably a good rule to consider the ligand to be the smaller of the two thus in a lectin sugar interaction, the sugar would be the ligand (even though it is attached to a much larger molecule, recognition is of the saccharide). (18 Nov 1997) |
|---|---|
| ligand binding site | The site on a protein's surface that binds a ligand; equivalent to the active site if the ligand is the substrate of an enzyme. (05 Mar 2000) |
| ligand gated ion channel | A transmembrane ion channel whose permeability is increased by the binding of a specific ligand, typically a neurotransmitter at a chemical synapse. The permeability change is often drastic, such channels let through effectively no ions when shut, but allow passage at up to 10exp7 ions sexp 1 when a ligand is bound. Recently, the receptors for both acetylcholine and GABA have been found to share considerable sequence homology, implying that there may be a family of structurally related ligand gated ion channels. (18 Nov 1997) |
| ligand induced endocytosis | The formation of coated pits and then coated vesicles as a consequence of the interaction of ligand with receptors, which then interact with clathrin and associated proteins (coatomers) on the cytoplasmic face of the plasma membrane and come together to form a pit. Not all coated vesicle uptake of receptors requires receptor occupancy. (18 Nov 1997) |
| ligand-gated channel | A class of ion channel's whose ionic permeability is regulated by cell membrane receptors that respond to specific extracellular chemical signals. (05 Mar 2000) |
| ligandin | A class of enzymes that catalyze the reaction of glutathione with an acceptor molecule (e.g., an arene oxide) to form an S-substituted glutathione; a key step in detoxification of many substances; start of the mercapturic acid pathway. Synonym: ligandin. (05 Mar 2000) |
| ligands | A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (12 Dec 1998) |
| ambident ligand | <chemistry> A ligand that can donate electrons through two or more atoms on their molecule. (05 Feb 1998) |
|---|---|
| cyanocobalamin beta-ligand transferase | <enzyme> Cytosolic enzyme utilizing fad, NADPH and reduced glutathione; forms glutathionylcobalamin from cyanocobalamin Registry number: EC 2.5.1.- Synonym: ccbl transferase (26 Jun 1999) |
| ELAM-1 ligand fucosyltransferase | <enzyme> Directs the expression of an elam-1 ligand; an alpha(1,3) fucosyltransferase Registry number: EC 2.4.1.- Synonym: elft protein, elft gene product (26 Jun 1999) |
Synonyms :
| ligand |
an atom or molecule or radical or ion that forms a complex around a central atom
Ãâó: wordnet.princeton.edu/perl/webwn
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| ligand-gated channel |
a protein channel that opens in response to the binding of a molecule (the ligand) to the protein, which causes a conformational change in the protein molecule. Cf. voltage-gated c.
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| ligand |
A molecule that can bind to another molecule in or on cells.
Ãâó: www.fao.org/docrep/003/X3910E/X3910E15.htm
|
| ligand |
A Lewis base that can coordinate to a metal atom.
Ãâó: xenon.che.ilstu.edu/genchemhelphomepage/glossary/l...
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| ligand |
any molecule that binds to the surface of another molecule, such as an immune cell RECEPTOR. For examples of receptors see CCR5, CXCR-4, CD4.
Ãâó: www.gmhc.org/health/glossary3.html
|
| ligand | an atom or molecule or radical or ion that forms a complex around a central atom |
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