| lathyrism | Disorder of collagen cross linking as a result of copper sequestration by nitriles. (Lysyl oxidase is a copper containing metalloenzyme). In animals, caused by eating toxic plants of genus Lathyris. (18 Nov 1997) |
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Synonyms : Neurolathyrism
| lathyrism |
a morbid condition seen in humans and other animals after excessive ingestion of seeds of the genus Lathyrus, which contain β-aminopropionitrile, an inhibitor of the enzyme lysyl oxidase. The disease is characterized by spastic paraplegia, pain, hyperesthesia, and paresthesia. Cf. lupinosis and osteolathyrism.
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