| 영문 | Klinefelter syndrome | 한글 | 클라인펠터증후군 |
|---|---|---|---|
| 설명 | 1942년 H.F. 클라인펠터가 기재한 성염색체이상증후군. 정상인의 성염색체형은 남성 XY, 여성 XX를 나타내지만, 이 증후군에서는 성염색체형이 XXY. XXYY, XXXXY 등의 여러 가지 이상한 형태를 나타낸다. 외성기-체격-성징 등의 특징적인 증세로 볼 때에 완전한 남성이 결혼하여 성생활까지 하였으나, 자식이 없자 부부가 함께 병원을 찾아가서 염색체를 검사해 보고 남자에게 이 증후군이 있음을 알게 되는 경우가 많다. 이 밖에 성인이 되어 나타나는 주요 증세를 들면, 작은고환, 여성형 유방증, 무정자증, 불임, 요중 고나도트로핀의 상승, 지능 저하 등이다. 치료는 2차 성징의 촉진을 위하여 호르몬요법에 의한 남성화를 시도한다. |
||
| Klinefelter | Harry F., Jr., U.S. Physician, *1912. See: Klinefelter's syndrome. (05 Mar 2000) |
|---|---|
| Klinefelter syndrome | <syndrome> A genetic syndrome observed in many mammals caused by the presence of an extra X chromosome in the male karyotype. The normal male is XY but in this disorder the chromosomal abnormality is XXY, and affects only males. Infertility is common. In humans, the infant appears normal at birth, but the defect usually becomes apparent in puberty when secondary sex characteristics fail to develop along with female escutcheon, gynaecomastia, tall stature, small testes, aspermatogonia and Leydig cell hyperplasia. It is characterised by small testes, feminine appearance, sterility (except in the case of genetic mosaics) and there is no effect on performance IQ but the verbal IQ can be affected. The genetic abnormality can be detected in 0.003% of spontaneous abortions and is associated with nondisjunction in paternal meiosis I (53%), maternal meiosis I (34%) and maternal meiosis II (9%). In a large number of patients the karyotype shows a 47,XXY constitution and in 10% of the cases there is mosaicism and some of these mosaics can be fertile. Patients with mosaic karyotypes that include 48,XXXY and 49,XXXXY can show short stature, mental retardation, hypogonadism and other abnormalities. Incidence: 1 in 1000 to 1 in 2000 newborn males. (17 Dec 1997) |
| klinefelter's syndrome | <syndrome> A condition characterised by small testes with hyalinization of the seminiferous tubules, variable degrees of masculinization, azoospermia and infertility, and increased urinary excretion of gonadotropin. Patients tend to be tall, with long legs, and about half have gybecomastia. It is associated typically with an xxy chromosome complement, although variants include xxyy, xxxy, xxxxy, and several mosaic patterns (xy/xxy, xxy, xxxy, etc.). (12 Dec 1998) |
Synonyms : Klinefelter's Syndrome, Klinefelter Syndromes, Klinefelters Syndrome, Syndrome, Klinefelter, Syndrome, Klinefelter's, Syndromes, Klinefelter
| Klinefelter's syndrome |
syndrome in males that is characterized by small testes and long legs and enlarged breasts and reduced sperm production and mental retardation; a genetic defect in which an extra X chromosome (XXY) is present in the male
출처: wordnet.princeton.edu/perl/webwn
|
|---|---|
| Klinefelter's syndrome |
a genetic disorder in which a man has at least 1 extra X chromosome in his cells, causing infertility and female characteristics
출처: www.american-depot.com/services/resources_gl_k.asp
|
| Klinefelter's syndrome |
a syndrome that results from an extra X chromosome in males. It involves hormonal imbalances, which cause characteristic changes in the sexual organs and body proportions.
출처: https://www.healthforums.com/library/1,1277,articl...
|
| Klinefelter's syndrome |
Chromosomal defect in males in which there is an extra X chromosome; manifestations may include underdeveloped testes, physical feminization, sterility, and mental retardation.
출처: www.indianpsychiatry.com/Glossary.htm
|
| Klinefelter's syndrome |
A genetic disorder in males caused by having an extra X chromosome. Males with this disorder may have larger than normal breasts, a lack of facial and body hair, a rounded body type, and small testicles. They may learn to speak much later than other children and may have difficulty learning to read and write. Klinefelter's syndrome increases the risk of developing testicular cancer.
출처: goldbamboo.com/glossary-1k.html
|
| kline | United States abstract expressionist painter (1910-1962) |
|---|---|
| kline | United States physician who first described the XXY-syndrome (born in 1912) |
| kline | syndrome in males that is characterized by small testes and long legs and enlarged breasts and reduced sperm production and mental retardation |
| kline | syndrome in males that is characterized by small testes and long legs and enlarged breasts and reduced sperm production and mental retardation |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|