| isozyme | <biochemistry> Variants of enzymes that catalyse the same reaction, but owing to differences in amino acid sequence can be distinguished by techniques such as electrophoresis or isoelectric focusing. Different tissues often have different isoenzymes. The sequence differences generally confer different enzyme kinetic parameters that can sometimes be interpreted as fine tuning to the specific requirements of the cell types in which a particular isoenzyme is found. (15 Oct 1997) |
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| isozyme |
one of various structurally related forms of an enzyme, each having the same mechanism but with differing chemical, physical, or immunological characteristics. For example, lactate dehydrogenase, a tetramer, exists as five isozymes arising from different combinations of its two kinds of subunits. Called also isoenzyme.
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