| 영문 | gout | 한글 | 통풍 |
|---|---|---|---|
| 설명 | 유전정보를 보관하는 물질인 DNA와 RNA 등을 이루는 핵산은 요산의 형태로 배설이 된다. 이것의 배설에는 여러 가지 효소가 작용한다. 이중에서 HGPRT (Hypoxanthine-Guanine Phosphoribosyl Transferase)라는 효소는 이미 배설이 되려고 요산으로 변환하는 과정의 물질을 다시 핵산으로 바꾸는 작용을 하는 효소이다. 통풍이란 이 HGPRT라는 효소 활성도가 감소되어 발생된다. 이 효소의 활성도가 감소되면 핵산의 배설단계에서 재사용이라는 단계가 없어지므로 과도한 요산의 생성이 있게 된다. 혈중에 과도한 요산이 존재하고 이 요산은 결정을 만들어서 관절 주위 및 연부 조직에 침착되어 격심한 발작성 관절통을 야기하는 급성 염증성 관절염을 일으키는 특징적인 병이다. 또 이 요산의 결정들이 콩팥이나 심장에 축적되어서 콩팥 및 심혈관계에 장애가 발생할 수도 있어 내과적 치료를 요하는 병이다. 유전 양식상 보통염색체 우성으로 유전하는 유전병이다. 보통염색체 우성 유전을 하지만 남자와 여자에서 표현률이 달라서 남자가 95%이상을 차지한다. |
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| ECG | Electro-Cardio-Graphy(-Gram); 심전도 = EKG 1. Conducting System Structu... |
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| ABC | absolute basophil count; absolute bone conduction; acalculous biliary colic; acid balance control; a... |
| PRAGMATIC | pregnancy, rheumatoid arthritis, acromegaly, glucose metabolism disorders, mechanical injury, amyloi... |
| JVP | [POMD P 49 - 52] 1) Jugular Vein Pressure 2) Jugular Venous Pulse ... |
| ABCD | airway, breathing, circulation, differential diagnosis (or defibrillate) [in cardiopulmonary resusci... |
| LIA | Large amplitude irregular activity |
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| gram-positive asporogenous rods, irregular | <microbiology> A group of irregular rod-shaped bacteria that stain gram-positive and do not produce endospores. (12 Dec 1998) |
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| irregular | Not regular; not conforming to a law, method, or usage recognised as the general rule; not according to common form; not conformable to nature, to the rules of moral rectitude, or to established principles; not normal; unnatural; immethodical; unsymmetrical; erratic; no straight; not uniform; as, an irregular line; an irregular figure; an irregular verse; an irregular physician; an irregular proceeding; irregular motion; irregular conduct, etc. Cf. Regular. "Mazes intricate, Eccentric, intervolved, yet regular Then most when most irregular they seem." (Milton) "Leading the men of Herefordshire to fight Against the irregular and wild Glendower." (Shak) "A flowery meadow through which a clear stream murmured in many irregular meanders." (Jones) Synonym: Immethodical, unsystematic, abnormal, unnatural, anomalous, erratic, devious, crooked, eccentric, unsettled, uneven, variable, changeable, mutable, desultory, disorderly, wild, immoderate, intemperate, inordinate, vicious. Origin: Pref. Ir- not + regular: cf. F. Irregulier. Source: Websters Dictionary (01 Mar 1998) |
| irregular astigmatism | Astigmatism in which different parts of the same meridian have different degrees of curvature. (05 Mar 2000) |
| irregular bone | One of a group of bones having peculiar or complex forms, e.g., vertebrae, many of the skull bones. Synonym: os irregulare. (05 Mar 2000) |
| irregular dentin | Morphologically irregular dentin formed in response to an irritant. Synonym: irregular dentin, irritation dentin, reparative dentin. (05 Mar 2000) |
| irregular emphysema | Emphysema that shows no consistent relationship to any portion of the acinus; always associated with fibrosis. (05 Mar 2000) |
| irregular nystagmus | A nystagmus in which the movements of the two eyes are dissimilar in direction, amplitude, and periodicity. Synonym: dysjunctive nystagmus, incongruent nystagmus, irregular nystagmus. (05 Mar 2000) |
| irregular pulse | Variation in rate of impulses in an artery due to cardiac arrhythmia. (05 Mar 2000) |
| irregular uterine lumen | <radiology> Synechiae, DES, post-op, neoplasm, normal variant, intravasation, endometrial hyperplasia, adenomyosis, embedded IUD, TB, uterine fistula, Gartner duct remnant (12 Dec 1998) |
| arthritis, gout | Joint inflammation caused by uric acid crystal deposits in the joint space An attack is usually extremely painful.The uric acid crystals are deposited in the joint fluid (synovial fluid) and joint lining (synovial lining). Intense joint inflammation occurs as white blood cells engulf the uric acid crystals, causing pain, heat, and redness of the joint tissues. The term gout commonly is used to refer to these painful arthritis attacks but gouty arthritis is only one manifeatation of gout. (12 Dec 1998) |
| calcium gout | <rheumatology> Chondrocalcinosis, chronic recurrent arthritis clinically similar to gout. (27 Sep 1997) |
| masked gout | latent gout |
| retrocedent gout | An obsolete term for the occurrence of severe gastric, cardiac, or cerebral symptoms during an attack of gout, especially when the joint and other symptoms suddenly subside at the same time. Saturnine gout, gout occurring in a person with lead poisoning. Synonym: lead gout. Secondary gout, gout resulting from increased serum uric acid levels as a result of an antecedent disease, such as a proliferative disease of the blood and bone marrow, lead poisoning, or prolonged chronic renal failure (on dialysis). Tophaceous gout, gout in which deposits of uric acid and urates occur as gouty tophi. (05 Mar 2000) |
| gout | <rheumatology> Recurrent acute arthritis of peripheral joints caused by the accumulation of monosodium urate crytals. Often presents as pain and swelling confined to one joint. The big toe joint is commonly affected. The arthritis occurs secondary to an inherited abnormality of purine metabolism, resulting in the deposition of uric acid crystals (sodium urate) within the joint space and articular cartilage. Usually due to overproduction of uric acid but may be a result of under excretion. The problems partly arise because neutrophils release lysosomal enzymes as a result of damage to the phagosome membrane by ingested crystals: colchicine acts to reduce the attack by inhibiting lysosome phagosome fusion. (18 Nov 1997) |
| gout arthritis | <rheumatology> Recurrent acute arthritis of peripheral joints caused by the accumulation of monosodium urate crytals. Often presents as pain and swelling confined to one joint. The big toe joint is commonly affected. The arthritis occurs secondary to an inherited abnormality of purine metabolism, resulting in the deposition of uric acid crystals (sodium urate) within the joint space and articular cartilage. Usually due to overproduction of uric acid but may be a result of under excretion. The problems partly arise because neutrophils release lysosomal enzymes as a result of damage to the phagosome membrane by ingested crystals: colchicine acts to reduce the attack by inhibiting lysosome phagosome fusion. (18 Nov 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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