| PHLOP | polymerase-halt-mediated linkage of primers |
|---|---|
| LIS | laboratory information system; lateral intercellular space; left intercostal space; library informat... |
| LISS | low-ionic-strength saline |
| Ii | Ionic |
|---|---|
| IS | Ionic Strength |
| LISS | Low ionic strength solutions |
| DLS | Dimer Linkage Structure |
| LD | Linkage Disequilibrium |
| non-ionic contrast media | <radiology> A class of radiographic contrast media which do not ionise in solution, thereby decreasing effective osmolarity and toxicity. (05 Mar 2000) |
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| ionic | Relating to an ion. (05 Mar 2000) |
| ionic coupling | <chemistry> The same as electrical coupling. (18 Nov 1997) |
| ionic medication | Movement of ions as a result of an applied electric field. For example the delivery of a charged molecule from the end of a micropipette without hydraulic flow. (18 Nov 1997) |
| ionic strength | Symbolised as g/2 or I and set equal to 0.5σmizi2, where mi equals the molar concentration and zi the charge of each ion present in solution; if molar concentrations (ci) are used instead of molality (and the solution is dilute), then I == 0.5(1/ρo)σcizi2 where ρo is the density of the solvent; a number of biochemically important events (e.g., protein solubility and rates of enzyme action) vary with the ionic strength of a solution. (05 Mar 2000) |
| amide linkage | <biochemistry> This is a carboxylic acid containing an amino group (-NH2). In an alpha amino acid, the amino group is attached to the carbon atom directly beside the carboxyl group. (09 Oct 1997) |
| map, linkage | A map of the genes on a chromosome based on linkage analysis. A linkage map does not show the physical distances between genes but rather their relative positions, as determined by how often two gene loci are inherited together. The closer two genes are (the more tightly they are linked), the more often they will be inherited together. Linkage distance is measured in centimorgans (cm). (12 Dec 1998) |
| genetic linkage | <genetics> The term refers to the fact that certain genes tend to be inherited together, because they are on the same chromosome. Thus parental combinations of characters are found more frequently in offspring than nonparental. Linkage is measured by the percentage recombination between loci, unlinked genes showing 50% recombination. See: linkage equilibrium, linkage disequilibrium. (18 Nov 1997) |
| glucosidic linkage | <biochemistry> The linkages between dextrose molecules in a glucoside compound which must be hydrolysed (broken apart) to produce the dextrose molecules. (09 Oct 1997) |
| medical record linkage | The creation and maintenance of medical and vital records in multiple institutions in a manner that will facilitate the combined use of the records of identified individuals. (12 Dec 1998) |
| phosphodiester linkage | <biochemistry> A chemical linkage in which two alcohols are esterically boundto a bridging molecule of phosphoric acid. (31 Dec 1997) |
| Y-linkage | The state of a genetic factor (gene) being borne on the Y chromosome. This idea is analogous with X-linkage but since the Y chromosome does not fully take part in chiasma formation and recombination, it not amenable to analysis by conventional linkage methods. Little is known about its content. There is a gene for the H-Y antigen, and indirect arguments suggest that there is a principle that determines the formation of the testis and masculinization of the foetus but its localization, though narrowing the limits, remains elusive. (05 Mar 2000) |
| linkage | <genetics> Tendency for two or more non-allelic genes to be inherited together, because they are located more or less closely on the same chromosome. Thus parental combinations of characters are found more frequently in offspring than nonparental. Linkage is measured by the percentage recombination between loci. (04 Jul 1999) |
| linkage analysis | <genetics> Study aimed at establishing linkage between genes. Today linkage analysis serves as a way of gene-hunting and genetic testing. (12 Dec 1998) |
| linkage disequilibrium | <genetics> The occurrence of some genes together, more often than would be expected. Thus, in the HLA system of histocompatibility antigens, HLA A1 is commonly associated with B8 and DR3 and A2 with B7 and DR2, presumably because the combination confers some selective advantage. (18 Nov 1997) |
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