| 영문 | pH, hydrogen ion concentration | 한글 | 수소이온농도지수 |
|---|---|---|---|
| 설명 | 혈액이나 소변에서 실시하는 검사항목. pH검사는 인체의 체액의 산성, 알칼리성을 알아보는 중요한 검사이다. 인체는 약알칼리성에 속하나, 이보다 pH의 증가나 감소가 나타날 경우, 생명에 위험이 발생한다. 인체내에는 이런 산도의 증감을 막기위해, 이른바 완충제들이 많이 존재하며, 특히 허파와 콩팥이 완충작용을 수행하는 주요기관이다. 콩팥은 산도가 높을 경우, 소변에서 산도를 증가시켜 배출함으로써 혈액내의 알칼리성 농도가 증가하도록 한다. 또한 허파에서도, 혈액내에 산도가 증가시 호흡을 증가함으로써 밖으로 산의 배출을 증가시킨다. 이런 허파와 콩팥의 균형은 아주 적절히 이루어지고 있으며, 어느 한 기관의 이상이 발생하면, 이런 균형은 깨어지기 쉽다. |
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| 영문 | ion | 한글 | 이온 |
|---|---|---|---|
| 설명 | 분자를 전기분해할 때 분리되는, 전기를 띤 미립자로서 양전기를 띤 양이온과 음전기를 띤 음이온이 있다. |
||
| g-ion | gram-ion |
|---|---|
| ISS | idiopathic short stature; injury severity score; International Society of Surgery; ion-scattering sp... |
| ROC | Receptor Operated Channel |
| VSC | Voltage Sensitive Channel |
| Ca2+-blocker | calcium channel blocker |
| KATP channel | ATP sensitive potassium channel |
|---|---|
| BK channel | K channel |
| ASIC | acid sensing ion channel |
| CRC | Ca(2+)-release channel |
| CRC | Calcium Release Channel |
channel-shoulder-pin attachment
| ion channel gating | The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability. (12 Dec 1998) |
|---|
| channel gating | <physiology> Small currents in the membrane just prior to the increase in ionic permeability, due to the movement of charged particles within the membrane. So called because they open the gates for current flow through ion channels. (20 Mar 1998) |
|---|---|
| gated ion channel | <physiology> Transmembrane proteins of excitable cells, that allow a flux of ions to pass only under defined circumstances. Channels may be either voltage gated, such as the sodium channel of neurons or ligand gated such as the acetylcholine receptor of cholinergic synapses. Channels tend to be relatively ion specific and allow fluxes of typically 1000 ions to pass in around 1ms, they are thus much faster at moving ions across a membrane than transport ATPases. (05 May 1997) |
| voltage gated ion channel | <physiology> A transmembrane ion channel whose permeability to ions is extremely sensitive to the transmembrane potential difference. These channels are essential for neuronal signal transmission and for intracellular signal transduction. See: sodium channel. (18 Nov 1997) |
| ion channel | <cell biology> A transmembrane pore that presents a hydrophilic channel for ions to cross a lipid bilayer down their electrochemical gradients. Some degree of ion specificity is usually observed and typically a million ions per second may flow. Channels may be permanently open, like the potassium leak channel or they may be voltage gated, like the sodium channel or ligand gated like the acetylcholine receptor. (27 Oct 1998) |
| ligand gated ion channel | A transmembrane ion channel whose permeability is increased by the binding of a specific ligand, typically a neurotransmitter at a chemical synapse. The permeability change is often drastic, such channels let through effectively no ions when shut, but allow passage at up to 10exp7 ions sexp 1 when a ligand is bound. Recently, the receptors for both acetylcholine and GABA have been found to share considerable sequence homology, implying that there may be a family of structurally related ligand gated ion channels. (18 Nov 1997) |
| cardiac gating | Using an electronic signal from the cardiac cycle to trigger an event, such as in imaging separate phases of cardiac contraction. (05 Mar 2000) |
| gating | 1. In a biological membrane, the opening and closing of a channel, believed to be associated with changes in integral membrane proteins. 2. A process in which electrical signals are selected by a gate, which passes such signals only when the gate pulse is present to act as a control signal, or passes only the signals that have certain characteristics. See: gate. (05 Mar 2000) |
| gating current | <physiology> Small currents in the membrane just prior to the increase in ionic permeability, due to the movement of charged particles within the membrane. So called because they open the gates for current flow through ion channels. (20 Mar 1998) |
| gating mechanism | Occurrence of the maximum refractory period among cardiac conducting cells approximately 2 mm proximal to the terminal Purkinje fibres in the ventricular muscle, beyond which the refractory period is shortened through a sequence of Purkinje cells, transitional cells, and muscular cells; gating mechanism may be a cause of ventricular aberration, bidirectional tachycardia, and concealed extrasystoles, a mechanism by which painful impulses may be blocked from entering the spinal cord. Compare: gate-control theory. (05 Mar 2000) |
| calcium channel | <physiology> A membrane channel that is specific for calcium. It is a voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorised as l, t, n, or p types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. (12 May 2002) |
| calcium channel agonist | <pharmacology> Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in vascular smooth muscle and/or cardiac muscle cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture. (12 Dec 1998) |
| calcium channel antagonist | <pharmacology> A class of drugs that act by selective inhibition of calcium ion influx through or across cell membranes or on the release and binding of calcium in intracellular pools. Calcium channel blockers are used primarily in the treatment of certain heart conditions and stroke. As they are inducers of vascular and other smooth muscle relaxation, they are also used in the treatment of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms. Synonym: calcium antagonist, calcium channel-blocker, slow channel-blocking agent. (12 May 2002) |
| calcium channel-blocker | <pharmacology> A class of drugs that act by selective inhibition of calcium ion influx through or across cell membranes or on the release and binding of calcium in intracellular pools. Calcium channel blockers are used primarily in the treatment of certain heart conditions and stroke. As they are inducers of vascular and other smooth muscle relaxation, they are also used in the treatment of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms. Synonym: calcium antagonist, calcium channel-blocker, slow channel-blocking agent. (12 May 2002) |
| voltage-gated channel | A class of ion channel's that open and close in response to change in the electrical potential across the plasma membrane of the cell; voltage-gated Na+ c.'s are important for conducting action potential along nerve cell processes. (05 Mar 2000) |
| channel | A furrow, gutter, or groovelike passageway. See: canal. Origin: L. Canalis (05 Mar 2000) |
Synonyms : Gatings, Ion Channel, Ion Channel Gatings
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|