| 영문 | antihypertensive drug | 한글 | 고혈압약, 항고혈압제 |
|---|---|---|---|
| 설명 | 고혈압의 치료에 사용하며 높은 혈압을 낮추는 약물을 말한다. 고혈압약에는 혈관평활근에 직접 작용하여 이완시키는 혈관확장제(히드라라진), 교감신경의 활동을 어디선가 차단하는 약물(레세르핀, 메틸도파, 프로프라노롤), 이뇨제(프로세미드, 에타크린산)이 사용된다. |
||
| 영문 | antimalarial drug | 한글 | 말라리아약, 항말라리아제 |
|---|---|---|---|
| 설명 | 말라리아 치료에 쓰는 약. 키니네, 클로로퀸, 프리마퀸 따위가 있다. 말라리아 원충의 발육주기에 대응해서 약물이 있으나 대부분은 병용요법에 따라서 말라리아 치료를 한다. 모기에 의한 포자체감염에 대한 항포자체 약은 독성 등의 문제가 있어서 아직 없다. 적혈구내에서의 환상체, 번식체에만 작용하는 것(항번식체 약은 클로로퀸, 피리메타민, 클로로구아나이드, 키니네)은 적혈구 외의 발육은 억제하지 않으므로 감염을 완전히 저지되지 않는다. 적혈구내외의 원충에 작용해 완전히 감염을 억제하는 것(파마킨, 펜타킨, 프리마킨), 혈중의 생식체를 죽이는 것(대부분의 항말라리아제)은 모기에 의한 타인으로의 전염원은 끊기는데 환자자신의 증상은 변화하지 않는다. |
||
| 영문 | drug | 한글 | 약, 약물, 약제 |
|---|---|---|---|
| 설명 | 1. 병, 기타 병적 상태의 진단, 치료, 예방이나 고통의 경감, 또는 생리적, 병리적 상태를 호전시키는 것을 목적으로 사람 또는 동물에 투여되는 화합물. 약리학에서는 치료약만이 아니라, 생체에 주어졌을 때 어떠한 반응을 나타내는 화학물질 모두를 약물이라고 한다. 작용이 강하고 안전성이 낮은 순서로 독약-극약-보통약으로 구분하고 있다. 약물치료에 영향을 미치는 인자로서, 생체쪽 인자로는 개체차, 연령, 체중 등이 있고, 약물쪽 인자로서는 투여방법, 투여량, 병용되고 있는 다른 약물 등이 있다. 2. 약의 재료가 되는 물질. 3. 여러 가지 약재를 섞어 조제한 약. |
||
| 영문 | drug resistance | 한글 | 약물내성 |
|---|---|---|---|
| 설명 | 1. 화학요법제나 항생물질의 어떤 일정 농도로 세균을 죽이거나 증식저해를 받는 것을 이 화학요법제나 항생물질에 감수성이 있다고 하는데, 이 감수성이 없게 된 생태를 저항성이라든가 내성이라고 말한다. 따라서 변이미생물의 약제에 대한 자항성이라든가 내성이라고 말한다. 2. 의약품을 계속 복용하면 점차 증량하지 않으면 효력이 나타나지 않는 성질. 이러한 때를 약제내성이 생겼다고 한다. 모든 미생물은 감수성을 가지는 약물에 의하여 사멸되지만, 소수의 것은 살아남아 그것이 진화됨으로써 사멸하지 않는 수가 있다. 또, 최초에는 감수성을 가지고 있던 균이 차차 내성균으로 되기도 한다. 많은 병원균은 감수성이 있는 의약품에 대하여 내성이 생긴다. 가장 고도의 내성균이 생기기 쉬운 것은 스트렙토마이신인데 결핵균과 그람음성균에 대하여 쉽게 내성이 생긴다. 페니실린이나 테트라시클린(아크로마이신) 등의 항생물질도 내성이 생기기 쉬우므로, 사용할 때는 적응을 잘 확인하여 필요량을 정하고 연용을 피한다. 같은 효과가 있는 다른 종류의 약제를 소량씩 2, 3종 병용하면 내성의 발생이 크게 억제된다는 것이 알려져 있다. 결핵약으로서 스트렙토마이신과 파스, 또는 이소니아지드를 병용하는 것 등이 그 예이다. |
||
| 영문 | drug dependence | 한글 | 약물의존(성) |
|---|---|---|---|
| 설명 | 어떤 종류의 약물을 반복해서 사용하는 동안 그 약의 사용을 중지할 수 없게 되는 상태. 의존의 정도가 심해지면 약 없이는 생활할 수 없는 상태에 빠지고, 그 결과 법을 어기면서까지 약을 구입하게 된다. 이전에는 약물만성중독, 약물남용, 약물습관성이라는 개념으로 나누어져 있었지만, WHO에서는 이것들을 모두 포함시켜서 약물의존이라 하였다. 상태에 의한 분류라 약물작용에 의한 분류가 있다. 상태에 의한 것은 1.정신적 의존: 약물의 사용을 중지하면 불안감-우울감-초조감 등의 심리적인 증상이 나타나 다시 약물을 찾게 되는 경우. 약을 끊었을 경우에 나타나는 신체증상인 금단증상은 나타나지 않으며, 약물의 지속적 복용에 의해서 점차 약물에 대한 신체의 반응이 줄어드는 현상인 약물의 내성도 나타나지 않는다. 2.신체적 의존: 약물 사용을 중지하면 신체적인 장애, 즉 금단증상을 일으키고 그 고통을 달래기 위해 약물을 찾게 되는 경우이다. 대부분 내성이 나타나는데 개별적으로 나타나는 경우도 있지만 주로 병행해서 나타난다. |
||
| IND | indomethacin; industrial medicine; investigational new drug |
|---|---|
| IDDF | investigational drug data form |
| IDS | iduronate sulfatase; immune deficiency state; inhibitor of DNA synthesis; integrated delivery system... |
| DA | dark adaptation; dark agouti [rat]; daunomycin; degenerative arthritis; delayed action; Dental Assis... |
| IDE | insulin-degrading enzyme; investigational device exemption |
| IND | Investigational New Drug |
|---|---|
| IND | Investigational New Drug Application |
| NDA | New Drug Application |
| IDE | Investigational Device Exemption |
| NJ | A/New Jersey |
| investigational new drug | Status given an experimental drug after the FDA approves an application for testing it in people. (09 Oct 1997) |
|---|---|
| investigational new drug application | An application that must be submitted to a regulatory agency (the FDA in the united states) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (12 Dec 1998) |
| drugs, investigational | Drugs which have received FDA approval for human testing but have yet to be approved for commercial marketing. This includes drugs used for treatment while they still are undergoing clinical trials (treatment ind). The main heading includes drugs under investigation in foreign countries. (12 Dec 1998) |
|---|---|
| drug-drug interaction | The effects that occur when two or more drugs are used together. Such effects include changes of absorption in the digestive tract, changes in rate of the drugs' breakdown in the liver, new or enhanced side effects and changes in the drugs' activity. (09 Oct 1997) |
| camelids, new world | Ruminant mammals of south america. They are related to camels. (12 Dec 1998) |
| papua new guinea | A country consisting of the eastern half of the island of new guinea and adjacent islands, including new britain, new ireland, the admiralty islands, and new hanover in the bismarck archipelago; bougainville and buka in the northern solomon islands; the d'entrecasteaux and trobriand islands; woodlark (murua) island; and the louisiade archipelago. It became independent on september 16, 1975. Formerly, the southern part was the Australian territory of papua, and the northern part was the un trust territory of new guinea, administered by Australia. They were administratively merged in 1949 and named papua and new guinea, and renamed papua new guinea in 1971. (12 Dec 1998) |
| new | 1. Having existed, or having been made, but a short time; having originated or occured lately; having recently come into existence, or into one's possession; not early or long in being; of late origin; recent; fresh; modern; opposed to old, as, a new coat; a new house; a new book; a new fashion. "Your new wife." 2. Not before seen or known, although existing before; lately manifested; recently discovered; as, a new metal; a new planet; new scenes. 3. Newly beginning or recurring; starting anew; now commencing; different from has been; as, a new year; a new course or direction. 4. As if lately begun or made; having the state or quality of original freshness; also, changed for the better; renovated; unworn; untried; unspent; as, rest and travel made him a new man. "Steadfasty purposing to lead a new life." (Bk. Of Com. Prayer) "Men after long emaciating diets, fat, and almost new." (Bacon) 5. Not of ancient extraction, or of a family of ancient descent; not previously kniwn or famous. 6. Not habituated; not familiar; unaccustomed. "New to the plow, unpracticed in the trace." (Pope) 7. Fresh from anything; newly come. "New from her sickness to that northern air." (Dryden) New birth. See Birth. New Church, or New Jerusalem Church, the church holding the doctrines taught by Emanuel Swedenborg. See Swedenborgian. New heart, an old name for the formation immediately above the coal measures or strata, now divided into the Permian and Trias. See Sandstone. New style. See Style. New testament. See Testament. New world, the land of the Western Hemisphere; so called because not known to the inhabitants of the Eastern Hemisphere until recent times. Synonym: Novel, recent, fresh, modern. See Novel. Origin: OE. OE. Newe, AS. Niwe, neowe; akin to D. Nieuw, OS. Niwi, OHG. Niuwi, G. Neu, Icel. Nr, Dan. & Sw. Ny, Goth. Niujis, Lith. Naujas, Russ. Novuii, Ir. Nua, nuadh, Gael. Nuadh, W. Newydd, Armor. Nevez, L. Novus, gr, Skr. Nava, and prob. To E. Now. 263. See Now, and cf. Announce, Innovate, Neophyte, Novel. Source: Websters Dictionary (01 Mar 1998) |
| new brunswick | A province of eastern canada, one of the maritime provinces with nova scotia, prince edward island, and sometimes newfoundland. Its capital is fredericton. It was named in honor of king george III, of the house of hanover, also called brunswick. (12 Dec 1998) |
| new caledonia | A group of islands in melanesia constituting a french overseas territory. The group includes new caledonia (the main island), ile des pins, loyalty island, and several other islet groups. The capital is noumea. It was discovered by captain cook in 1774 and visited by various navigators, explorers, and traders from 1792 to 1840. Occupied by the french in 1853, it was set up as a penal colony 1864-94. In 1946 it was made a french overseas territory. It was named by captain cook with the 5th and 6th century a.d. Latin name for scotland, caledonia. (12 Dec 1998) |
| new combination | The new name that results from the transfer of a microorganism from one genus to another; the generic name changes but, in most cases, the specific epithet remains the same. (05 Mar 2000) |
| new duck disease | A contagious disease of young ducks and turkeys caused by the bacterium Pasteurella anatipestifer and characterised in ducks by ocular and nasal discharges, coughing and sneezing, and incoordination, and in turkeys by dyspnea, droopiness, lameness, and a twisted neck. Synonym: new duck disease. (05 Mar 2000) |
| new england | The geographic area of new england in general and when the specific state or states are not indicated. States usually included in this region are maine, new hampshire, vermont, massachusetts, connecticut, and rhode island. (12 Dec 1998) |
| new growth | <oncology, pathology> New and abnormal growth of tissue, which may be benign or cancerous. (16 Dec 1997) |
| new guinea | Originally an island of the malay archipelago, the second largest island in the world. It divided, west new guinea becoming part of indonesia and east new guinea becoming papua new guinea. (12 Dec 1998) |
| New Hampshire rule | Pioneering American test of criminal responsibility (1871): "if the [criminal] act was the offspring of insanity, a criminal intent did not produce it." (05 Mar 2000) |
| new methylene blue | A basic thiazin dye, C18H22N3SCl, used for supravital staining of reticulocytes in blood smears. (05 Mar 2000) |
| new mutation | Redundant term for a heritable trait present in the offspring but in neither parent, i.e., not a pre-existing mutant form inherited. (05 Mar 2000) |
Synonyms : Investigational New Drug Applications
| investigational new drug |
A program that allows a drug developer to give physicians an experimental drug for people who have no other treatment options, once the drug has shown signs that it works and is safe.
출처: www.aegis.com/pubs/cria/2003/CR030902.html
|
|---|---|
| investigational new drug |
a drug allowed by the US Food and Drug Administration (FDA) to be used in clinical trials, but not approved for sale to the general public.
출처: www.luhs.org/health/topics/glossary/i.htm
|
| investigational new drug |
The pre-approval status of an experimental drug or biologic (eg vaccine) after the US Food and Drug Administration (FDA) agrees that it can be tested in people (generally done in order to collect sufficiently data for licensure.) "IND" often refers to the application to obtain this pre-approval status.
출처: www.sabin.org/vaccine_science_GlossaryH_K.htm
|
| investigational new drug |
Following clearance of an Investigational (preclinical) New Drug submission (IND), manufacturers may be authorized to supply a new drug to a qualified investigator(s) specifically for the purpose of conducting clinical evaluations to obtain data about the safety and efficacy of that drug. Information required for a preclinical new drug submission is outlined in section C.08.005 of the Food and Drug Regulations.
출처: www.hc-sc.gc.ca/vetdrugs-medsvet/glossary_of_terms...
|
| investigational new drug |
The status of an experimental drug after the Food and Drug Administration agrees that it can be tested in people.
출처: www.aidsinfobbs.org/letters/i.html
|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|