| recon | the smallest unit of DNA capable of recombination [recombination + Gr. on quantum] |
|---|---|
| HFR | high-frequency recombination |
| RAG | ragweed; recombination activating gene |
| REC | receptor; recombination, recombinant [chromosome] |
| RECA | recombination protein A |
| HR | Homologous recombination |
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| RAG-1 | Recombination Activating Gene-1 |
| RAG | Recombination activating gene |
| RN | recombination nodule |
| RSS | Recombination signal sequences |
| intragenic complementation | Complementation between pieces of genetic material, each of which has a different defect within the same locus; the resultant product of each is defective and nonfunctional, but the defective products may associate to produce a product which has some activity. (05 Mar 2000) |
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| intragenic suppression | <molecular biology> The situation where a primary gene and the mutated gene that suppresses it lie within the same locus. (18 Nov 1997) |
| genetic recombination | <molecular biology> Formation of new combinations of alleles in offspring (viruses, cells or organisms) as a result of exchange of DNA sequences between molecules. It occurs naturally, as in crossing over between homologous chromosomes in meiosis or experimentally, as a result of genetic engineering techniques. (18 Nov 1997) |
| recombination | <molecular biology> The creation, by a process of intermolecular exchange, of chromosomes combining genetic information from different sources, typically two genomes of a given species. Site specific, homologous, transpositional and nonhomologous illegitimate) types of recombination are known. 1st ed (18 Nov 1997) |
| recombination coefficient | <radiobiology> The rate of recombination of positive ions with electrons (or negative ions) in a gas, per unit volume, divided by the product of the particle densities of the two species (positive ions and electrons/negative ions) involved. (09 Oct 1997) |
| recombination fraction | The proportion of progeny of a mating pair of specific genotype and coupling phase that are recombinant; there must be no differential selection among the possible types of progeny, and the recombination fraction should be the same regardless of the alleles involved or their coupling phase. (05 Mar 2000) |
| recombination frequency | The frequency at which crossingover occurs between two chromosomal loci--the probability that twoloci will become unlinked during meiosis. (09 Oct 1997) |
| recombination, genetic | Production of new arrangements of genes by various mechanisms such as assortment and segregation, crossing over, gene conversion, transformation, conjugation, transduction, f-duction, or mixed infection of viruses. (12 Dec 1998) |
| recombination nodule | <molecular biology> Protein containing assemblies of about 90 nm diameter placed at intervals in the synaptonemal complexes that develop between homologous chromosomes at the zygotene stage of meiosis. Some nodules may be associated with the site of recombination. (18 Nov 1997) |
| recombination radiation | <physics> Radiation produced when a free electron in a plasma is captured by an ion. (09 Oct 1997) |
| mitotic recombination | <genetics, molecular biology> Somatic crossing over. Crossing over can occur between homologous chromosomes during mitosis, but is very rare because the chromosomes do not normally pair. When it occurs it can lead to new combinations of previously linked genes. Although infrequent, mitotic recombination has been utilised for genetic analysis in Aspergillus and in studies on developmental compartments in Drosophila where the frequency of mitotic recombination can be increased by X irradiation. (18 Nov 1997) |
| high frequency recombination strain | A type of bacterial strain which is able to pass on genetic information to neighboring bacteria at a high rate. The high-frequency recombination strain (Hfr) is able to do this because it possesses the f plasmid and can therefore initiate bacterial conjugation. (09 Oct 1997) |
| homologous recombination | <molecular biology> Genetic recombination involving exchange of homologous loci. Important technique in the generation of null alleles (knockouts) in transgenic mice. (18 Nov 1997) |
| site-specific recombination | <molecular biology> A type of recombination that occurs between two specific short DNA sequences present in the same or in different molecules. An example is the integration and excision of _ prophage. (18 Nov 1997) |
| somatic recombination | One of the mechanisms used to generate diversity in antibody production is to rearrange the DNA in B-cells during their differentiation, a process that involves cutting and splicing the immunoglobulin genes. Somatic recombination via homologous crossing over occurs at a low frequency in Aspergillus, Drosphilia and Saccharomyces and in mammalian cells in culture. It may be detected through the production of homozygous patches or sectors after mitosis of cells heterozygous for suitable marker genes. (18 Nov 1997) |
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