| ¿µ¹® | mutation | ÇÑ±Û | µ¹¿¬º¯ÀÌ |
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| ¼³¸í | ¼¼Æ÷ÀÇ dna ÀÚüÀÇ º¯ÀÌ¿¡ ÀÇÇØ ÀϾ´Â ¼¼Æ÷º¯À̸¦ ¸»ÇÑ´Ù. ÀÌ·¯ÇÑ °æ¿ì µ¹¿¬º¯ÀÌ·Î ÀÏ¾î³ ¼¼Æ÷´Â ±× ÀÌÈÄ µþ¼¼Æ÷(daughter cell)¿¡¼µµ ±× º¯À̰¡ ¿©ÀüÈ÷ À¯ÁöµÇ¹Ç·Î Á¾(species)ÀÇ º¯È³ª, ȤÀº ¼¼Æ÷ÀÇ ¾Ç¼ºº¯È¯(malignant transformation)¿¡ °ü¿©ÇÑ´Ù. |
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| ARMS | adverse reaction monitoring system; amplification refractory mutation system |
|---|---|
| MF | magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s... |
| TFM | testicular feminization male; testicular feminization mutation; total fluid movement; transmission e... |
| Ts cell | suppressor T cell(= T8 cell) |
| CD8 | HIV suppressor cell count |
| ERIC | Enterobacterial Repetitive Intergenic Consensus |
|---|---|
| IGS | Intergenic Spacer |
| ISR | intergenic spacer region |
| IR | intergenic region |
| ARMS | Amplification Refractory Mutation System |
| suppressor mutation | <molecular biology> Mutation that alleviates the effect of a primary mutation at a different locus. May be through almost any mechanism that can give a primary mutation, but perhaps the most interesting class are the amber and ochre supressors, where the anticodon of the tRNA is altered so that it mis reads the termination codon and inserts an amino acid, preventing premature termination of the peptide chain. (18 Nov 1997) |
|---|---|
| intergenic complementation | Complementation between pieces of genetic material that regulate the same function, such as a multienzyme pathway, but have defects in regions of separate genetic function; such complementation permits synthesis of a normal end-product. (05 Mar 2000) |
| intergenic region | <molecular biology> DNA sequences located between genes that comprise a large percentage of the human genome with no known function. (09 Oct 1997) |
| intergenic suppression | The situation where a primary gene and the gene that suppresses it do not lie in the same chromosomal locus. Compare: intragenic suppression. (18 Nov 1997) |
| amber suppressor | <molecular biology> A tRNA molecule which suppresses amber mutations because it has mutated to recognise the amber codon UAG (which normally signals that the translation of mRNA into an amino acid chain should stop) as a signal for inserting whatever amino acid it carries into the chain. As a result, it can prevent the amino acid chain from ending before it is completed. (09 Oct 1997) |
| genes, suppressor | Genes that inhibit expression of a previous mutation. They allow the wild-type phenotype to be wholly or partially restored. (12 Dec 1998) |
| genes, suppressor, tumour | Genes that inhibit expression of the tumourigenic phenotype. They are normally involved in holding cellular growth in check. When tumour suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and deregulated growth is possible. (12 Dec 1998) |
| suppressor | A compound that suppresses the effects of mutation or suppresses what would be a normal course of events. (05 Mar 2000) |
| suppressor cell | <immunology> Lymphocyte class of cells suppressing T or B antigen dependent responses. (18 Nov 1997) |
| suppressor cells | Cells of the immune system that inhibit or help to terminate an immune response, e.g., suppressor macrophages and suppressor T-cells. Synonym: cytotoxic cell. (05 Mar 2000) |
| suppressor factor | <immunology> Factors released by T suppressor cells. See: suppressor mutation, ochre suppressor, opal suppressor. (19 Jan 1998) |
| suppressor factors, immunologic | Proteins, protein complexes, or glycoproteins secreted by suppressor T-cells that inhibit either subsequent T-cells, B-cells, or other immunologic phenomena. Some of these factors have both histocompatibility (I-j) and antigen-specific domains which may be linked by disulfide bridges. They can be elicited by haptens or other antigens and may be mass-produced by hybridomas or monoclones in the laboratory. (12 Dec 1998) |
| suppressor-sensitive mutant | A conditionally lethal, host range, bacteriophage mutant that produces nonsense codons and can replicate only in a host bacterium able to translate the nonsense codon; the mutation's effects are lethal (i.e., prevent replication of the virus) in a bacterium without such a suppressor mechanism. (05 Mar 2000) |
| suppressor T-cell | <immunology> See T-cells. (18 Nov 1997) |
| suppressor tRNA | The tRNA associated with a suppressor mutation. (05 Mar 2000) |
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