| MAOI | MonoAmine Oxidase Inhibitors |
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| IN | Integrase |
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| Int | Integrase |
| int | integrase gene |
| IN | integrase protein |
| AChE-I | acetylcholine esterase inhibitors |
| integrase inhibitors | Compounds which inhibit or antagonise biosynthesis or actions of integrase. (12 Dec 1998) |
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| HIV integrase inhibitors | Inhibitors of HIV integrase, an enzyme required for integration of viral DNA into cellular DNA. (12 Dec 1998) |
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| phage integrase family | <enzyme> Enzymes that mediate site specific recombination in prokaryotes. They fall into two families, phage integrases and resolvases. (18 Nov 1997) |
| HIV integrase | <enzyme> Enzyme of the human immunodeficiency virus that is required to integrate viral DNA into cellular DNA in the nucleus of a host cell. HIV integrase is a DNA nucleotidyltransferase encoded by the pol gene. Registry number: EC 2.7.7.- (12 Dec 1998) |
| HP1 integrase | <chemical> 337-residue polypeptide; amino acid sequence given in first source Synonym: site-specific integration protein hp1, haemophilus (26 Jun 1999) |
| integrase | <enzyme> The HIV enzyme that inserts HIV's genes into a cells normal DNA. Integrase operates after reverse transcriptase has created a DNA version of the RNA form of HIV genes present in virus particles. Drugs that block the action of integrase are under development. (18 Nov 1997) |
| integrase protein | <enzyme> An enzyme of the bacteriophage lambda (_) that catalyses the integration of phage DNA into the host DNA. (18 Nov 1997) |
| endonuclease-integrase | <enzyme> Part of the hiv pol gene polyprotein Registry number: EC 3.1.- Synonym: endonuclease-integrase, retroviral, hiv endonuclease-integrase, hiv-1 endonuclease protein p31 (26 Jun 1999) |
| adrenergic uptake inhibitors | Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (antidepressive agents, tricyclic) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. (12 Dec 1998) |
| blood coagulation factor inhibitors | Substances, usually endogenous, that act as inhibitors of blood coagulation. They may affect one or multiple enzymes throughout the process. As a group, they also inhibit enzymes involved in processes other than blood coagulation, such as those from the complement system, fibrinolytic enzyme system, blood cells, and bacteria. (12 Dec 1998) |
| Bowman Birk protease inhibitors | <pharmacology> Family of serine protease inhibitors found in seeds of leguminous plants and cereals. (18 Nov 1997) |
| carbonic anhydrase inhibitors | A class of compounds that reduces the secretion of h+ ions by the proximal kidney tubule through inhibition of carbonic anhydrase (carbonate dehydratase). Although their therapeutic use as diuretics is not frequent, they are used in clinical conditions where alkalinization of the urine is beneficial. Their most frequent application is in the reduction of intra-ocular pressure in the treatment of glaucoma. (12 Dec 1998) |
| reverse transcriptase inhibitors | Inhibitors of reverse transcriptase (RNA-directed DNA polymerase), an enzyme that synthesises DNA on an RNA template. (12 Dec 1998) |
| growth inhibitors | Endogenous or exogenous substances which inhibit the normal growth of human and animal cells or micro-organisms, as distinguished from those affecting plant growth (= plant growth regulators). (12 Dec 1998) |
| phosphodiesterase inhibitors | Compounds which inhibit or antagonise the biosynthesis or actions of phosphodiesterases. (12 Dec 1998) |
| monoamine oxidase inhibitors | A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. Although mao inhibitors are probably as effective as tricyclic antidepressants in the treatment of major depression, the complex, sometimes severe, and often unpredictable interactions between mao inhibitors and many other drugs and food-derived amines make their medical use difficult and potentially hazardous. (12 Dec 1998) |
Synonyms : Inhibitors, Integrase
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