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IN Integrase
Int Integrase
int integrase gene
IN integrase protein
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integrase <enzyme> The HIV enzyme that inserts HIV's genes into a cells normal DNA.
Integrase operates after reverse transcriptase has created a DNA version of the RNA form of HIV genes present in virus particles. Drugs that block the action of integrase are under development.
(18 Nov 1997)
integrase inhibitors Compounds which inhibit or antagonise biosynthesis or actions of integrase.
(12 Dec 1998)
integrase protein <enzyme> An enzyme of the bacteriophage lambda (_) that catalyses the integration of phage DNA into the host DNA.
(18 Nov 1997)
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phage integrase family <enzyme> Enzymes that mediate site specific recombination in prokaryotes. They fall into two families, phage integrases and resolvases.
(18 Nov 1997)
HIV integrase <enzyme> Enzyme of the human immunodeficiency virus that is required to integrate viral DNA into cellular DNA in the nucleus of a host cell. HIV integrase is a DNA nucleotidyltransferase encoded by the pol gene.
Registry number: EC 2.7.7.-
(12 Dec 1998)
HIV integrase inhibitors Inhibitors of HIV integrase, an enzyme required for integration of viral DNA into cellular DNA.
(12 Dec 1998)
HP1 integrase <chemical> 337-residue polypeptide; amino acid sequence given in first source
Synonym: site-specific integration protein hp1, haemophilus
(26 Jun 1999)
endonuclease-integrase <enzyme> Part of the hiv pol gene polyprotein
Registry number: EC 3.1.-
Synonym: endonuclease-integrase, retroviral, hiv endonuclease-integrase, hiv-1 endonuclease protein p31
(26 Jun 1999)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 2 ÆäÀÌÁö: 1
  • Integrase Inhibitors - »õâ Compounds which inhibit or antagonize biosynthesis or actions of integrase.
    Synonyms : Inhibitors, Integrase
  • Integrases - »õâ Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.
    Synonyms :
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integrase A little-understood enzyme that plays a vital role in the HIV-infection process. Integrase inserts HIV's genes into a cell's normal DNA. It operates after reverse transcriptase has created a DNA version of the RNA form of HIV genes present in virus particles. Substances that inhibit integrase are being studied in HIV-positive patients.
Ãâó: www.amfar.org/cgi-bin/iowa/bridge.html
integrase An HIV enzyme used by the virus to integrate its genetic material into the host cell's DNA. See also DNA; Enzyme.
Ãâó: www.aidsinfobbs.org/letters/i.html
integrase a viral enzyme that enables the integration of viral genetic material into a host cell's DNA.
Ãâó: cas.umkc.edu/psyc/motiv8/glossary.htm
integrase inhibitor Any agent that prevents the human immunodeficiency virus from inserting its viral DNA into host cell chromosomes.
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