| ¿µ¹® | edema | ÇÑ±Û | ºÎÁ¾ |
|---|---|---|---|
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| ¿µ¹® | insulin | ÇÑ±Û | Àν¶¸° |
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| ¼³¸í | ÀÌÀÚ ¶û°ÖÇѽº¼¶ÀÇ B¼¼Æ÷°¡ ÇÕ¼º-ºÐºñÇϴ ȣ¸£¸ó ´Ü¹éÁú, Æ÷µµ´çÀ» ±Û¸®ÄÚ°ÕÀ¸·Î ¹Ù²Ù´Â È£¸£¸ó´Ü¹éÁú·Î, ºÐÀÚ·®Àº 5,807ÀÌ´Ù. Ç÷ÁßÀÇ ´ç³óµµ »ó½ÂÀ¸·Î ÀÎÇÏ¿© ºÐºñ°¡ ÃËÁøµÈ´Ù. ±ÙÀ°-Áö¹æÁ¶Á÷-°£ µî Ç¥Àû¼¼Æ÷ÀÇ ¼ö¿ëü ´Ü¹éÁú°ú °áÇÕÇÏ¿© Á¤º¸¸¦ ¼¼Æ÷³»·Î Àü´ÞÇÔÀ¸·Î½á Ç÷¾× Áß¿¡¼ ´ç, ÁöÁú, ¾Æ¹Ì³ë»ê ´ë»ç¸¦ Á¶ÀýÇÑ´Ù. ´çÀÇ Á¶Á÷¿¡ ¹Þ¾Æµå¸®´Â °ÍÀ» ÃËÁøÇÏ¿© Ç÷´çÀ» ÀúÇϽÃŲ´Ù. »ý¼º-ºÐºñ·® ÀúÇÏ, Á¶Á÷¼¼Æ÷ÀÇ ¼ö¿ëü ºÎÁ·Àº °íÇ÷´çÀÇ ¿øÀÎÀÌ µÈ´Ù. ¶ÇÇÑ ¾Æ¹Ì³ë»êÀÇ Èí¼ö¿Í ´Ü¹éÁú, Áö¹æÀÇ ÇÕ¼ºÀ» ÃËÁøÇϸç Áö¹æºÐÇØ´Â ¾ïÁ¦ÇÑ´Ù. Àν¶¸°Àº ÀÌÀÚȰ¼º¼ººÐÀÇ ¾àǰÀ¸·Î¼ ´ç´¢º´ ¹× ±âŸ ÁúȯÀÇ Ä¡·á¿¡ »ç¿ëµÈ´Ù. Àν¶¸°À̶ó´Â ¸íĪÀº ¼¶À̶õ ¶æÀÇ ¶óƾ¾îÀÎ insula¿¡¼ ¿¬À¯ÇÑ´Ù. 1921³â ij³ª´ÙÀÇ ÀÇ»ç F.G. ¹êÆÃ°ú C.H. º£½ºÆ®¿¡ ÀÇÇÏ¿© óÀ½À¸·Î ÀÌÀÚ¿¡¼ äÃëµÇ¾ú°í, ±× ÈÄ Àν¶¸°ÀÇ °áÁ¤À» ¾ò°Ô µÇ¾ú´Ù. F. »ý°Å¿¡ ÀÇÇØ¼ ¼ÒÀÇ Àν¶¸°ÀÇ ±¸Á¶°¡ ¹àÇôÁ³´Âµ¥(1955), À̰ÍÀº ´Ü¹éÁú Áß¿¡¼´Â ÃÖÃÊ·Î ±¸Á¶½ÄÀÌ ¹àÇôÁø °ÍÀÌ´Ù. Æ÷µµ´çÀ¸·ÎºÎÅÍ ±Û¸®ÄÚ°ÕÀÇ »ý¼º, Æ÷µµ´çÀÇ »êÈ ¹× Áö¹æÀ¸·ÎÀÇ ÀüÈ µîÀ» ÃËÁøÇÏ´Â ÀÛ¿ëÀÌ ÀÖ´Ù. µû¶ó¼ Àν¶¸°ÀÇ ¼ö¿ë¾×À» ÁÖ»çÇϸé Ç÷´çÀÌ ÀúÇÏÇϹǷΠ´ç´¢º´ÀÇ Ä¡·á¿¡ ¾²ÀδÙ. ¶Ç Àν¶¸°À» ÇÇÇÏ¿¡ ´ë·® ÁÖ»çÇϸé È¥¼ö¿¡ ºüÁö´Â °ÍÀ» ÀÌ¿ëÇÏ¿© Á¤½Åº´ Ä¡·á¿¡ Àν¶¸°¼îÅ©¿ä¹ýÀ¸·Î¼ ¾²ÀδÙ. |
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| ¿µ¹® | IDDM(Insulin-Dependent Diabetes Mellitus) | ÇÑ±Û | Àν¶¸°ÀÇÁ¸´ç´¢º´ |
|---|---|---|---|
| ¼³¸í | IDDMÀº ´ç´¢º´ÀÇ Ä¡·á¿¡ ¹Ýµå½Ã Àν¶¸°ÀÌ ÇÊ¿äÇÑ °æ¿ì¸¦ ¸»ÇÑ´Ù. ÁÖ·Î ¿øÀÎÀÌ ÀÌÀÚ¿¡ ÀÖ´Â Àν¶¸°À» ºÐºñÇÏ´Â ¼¼Æ÷ÀÇ ÆÄ±«À̸ç ÀÌ·Î ÀÎÇØ¼ ´ç´¢º´ÀÇ Ä¡·áÁ¦·Î ¾²ÀÌ´Â Àν¶¸°ÀÇ ºÐºñ¸¦ ÃËÁøÇÏ´Â ¾à¹°ÀÌ ÀÌ IDDM¿¡¼´Â ¾²ÀÏ ¼ö°¡ ¾ø°í ¿ÀÁ÷ Àν¶¸°¸¸ÀÌ Ä¡·áÁ¦·Î ¾µ ¼ö°¡ ÀÖ´Ù. ÀüÇüÀûÀÎ Àν¶¸° ÀÇÁ¸Çü ´ç´¢º´Àº ¼Ò¾Æ¿¡¼ ÈçÈ÷ ¹ß»ýÇϰí Àν¶¸° ºÐºñ¼¼Æ÷ÀÇ ÆÄ±«¿¡ ÀÇÇØ¼ Àν¶¸° ºÐºñ´ÉÀº °ÅÀÇ ¾ø´Ù. |
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| HPE | hepatic portoenterostomy; high-permeability edema; history and physical examination; holoprosencepha... |
|---|---|
| NPH | 1) Neutral Protamine Hagedorn Insulin = Isophane Insulin Susp... |
| AITT | arginine insulin tolerance test; augmented insulin tolerance test |
| IRI | immunoreactive insulin; insulin resistance index |
| IRS | immunoreactive secretion; infrared spectrophotometry; insulin receptor species; insulin receptor sub... |
| BE | Brain edema |
|---|---|
| CSME | Clinically significant macular edema |
| CME | Cystoid macular edema |
| EPH | Edema Proteinuria Hypertension |
| HANE | Hereditary Angio Neurotic Edema |
IGF-II : insulin like growth factor-IIÀÇ ¾àÀÚ. ¸¹Àº Àå±â¿Í Á¶Á÷¿¡ ÀÛ¿ëÇÏ¿© ´Ü¹é ÇÕ¼º°ú DNA, RNAÀÇ ÇÕ¼ºÀ» Áõ°¡½ÃÄÑ ¼¼Æ÷ÀÇ ¼ö¿Í ¾çÀ» Áõ°¡
| edema | <clinical sign> The presence of abnormally large amounts of fluid in the intercellular tissue spaces of the body, usually applied to demonstrable accumulation of excessive fluid in the subcutaneous tissues. Oedema may be localised, due to venous or lymphatic obstruction or to increased vascular permeability or it may be systemic due to heart failure or renal disease. Collections of oedema fluid are designated according to the site, for example ascites (peritoneal cavity), hydrothorax (pleural cavity) and hydropericardium (pericardial sac). Massive generalised oedema is called anasarca. Origin: Gr. Oide ma = swelling (18 Nov 1997) |
|---|---|
| edema, cardiac | A manifestation of congestive heart failure caused by increased venous and capillary pressures and often associated with the retention of sodium by the kidneys. (12 Dec 1998) |
| amorphous insulin zinc suspension | Sterile suspension of insulin in buffered water for injection, modified by the addition of zinc chloride such that the solid phase of the suspension is amorphous; it contains 40 or 80 units per ml; the duration of action is equivalent to that of insulin injection. Synonym: amorphous insulin zinc suspension, semilente insulin. (05 Mar 2000) |
| anti-insulin | A factor, usually an antibody, which antagonises the action of insulin. (05 Mar 2000) |
| anti-insulin antibody | A serologic blood test that is used to detect antibodies to insulin. This test is performed in insulin dependent diabetics who exhibit insulin resistance. The presence of antibodies denotes a positive result. (27 Sep 1997) |
| biphasic insulin | <protein> A type of insulin that is a mixture of intermediate- and fast-acting insulin. (09 Oct 1997) |
| receptors, insulin | Cell surface proteins that bind insulin and trigger intracellular changes which influence the behaviour of cells. The best understood physiological consequence of insulin receptor activation is increased transport of glucose into most cells, which controls the rate of carbohydrate metabolism. The insulin receptor is a multifunctional protein complex that has intrinsic tyrosine kinase activity and is capable of autophosphorylation. (12 Dec 1998) |
| receptors, insulin-like-growth factor I | Specific proteins on or in cells to which insulin-like growth factor I (somatomedin c) binds and thereby modifies the function of the cells. These receptors contain transmembrane and cytosolic domains, bind igf-I preferentially, and have high-affinity sites for igf-II. The alpha-subunit has a mw of 130 kD and the beta subunit possesses tyrosine kinase activity. (12 Dec 1998) |
| receptors, insulin-like-growth-factor II | Specific proteins on or in cells to which insulin-like growth factor II and mannose-6-phosphate bind and thereby modify the function of the cells. These receptors have a mw of 250 kD and possess no tyrosine kinase activity. (12 Dec 1998) |
| regular insulin | A rapidly acting form of insulin which is a clear solution and may be administered intravenously as well as subcutaneously; may be mixed with longer acting forms of insulin to extend the duration of effect. Onset of effect occurs in 1/2 to 1 hour, peak effects are observed in 2 to 3 hours, and the duration of effect is about 5 to 7 hours. Synonym: globin insulin. (05 Mar 2000) |
| regular insulin injection | A preparation that may contain 20, 40, 80, 100, or 500 USP insulin units per ml, although the trend is toward standardizing all insulin preparations at 100 units per ml; it is administered subcutaneously, occasionally intravenously, and has a rapid onset of action, has a brief duration (5 to 7 hours), and is compatible for mixing with long-acting insulin preparations; used in the treatment of diabetic acidosis and insulin coma. Synonym: regular insulin injection. (05 Mar 2000) |
| globin insulin | A rapidly acting form of insulin which is a clear solution and may be administered intravenously as well as subcutaneously; may be mixed with longer acting forms of insulin to extend the duration of effect. Onset of effect occurs in 1/2 to 1 hour, peak effects are observed in 2 to 3 hours, and the duration of effect is about 5 to 7 hours. Synonym: globin insulin. (05 Mar 2000) |
| globin zinc insulin | A sterile solution of insulin modified by the addition of zinc chloride and globin; it contains 40 or 80 units per ml; duration of action is about 18 hours. Human insulin, a protein that has the normal structure of insulin produced by the human pancreas, prepared by recombinant DNA techniques and by semisynthetic processes. Immunoreactive insulin (IRI), that portion of insulin in blood measured by immunochemical methods for the hormone; presumed to represent the free (unbound) and biologically active fraction of total blood insulin. Isophane insulin, a modified form of insulin composed of insulin, protamine, and zinc; an intermediately acting preparation used for the treatment of diabetes mellitus. Synonym: NPH insulin. (05 Mar 2000) |
| crystalline insulin zinc suspension | A long-acting insulin suspension, obtained from beef, with an approximate time of onset of 7 hours and a duration of action of 36 hours. Synonym: crystalline insulin zinc suspension. (05 Mar 2000) |
| prompt insulin zinc suspension | Sterile suspension of insulin in buffered water for injection, modified by the addition of zinc chloride such that the solid phase of the suspension is amorphous; it contains 40 or 80 units per ml; the duration of action is equivalent to that of insulin injection. Synonym: amorphous insulin zinc suspension, semilente insulin. (05 Mar 2000) |
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