| ¿µ¹® | IDDM(Insulin-Dependent Diabetes Mellitus) | ÇÑ±Û | Àν¶¸°ÀÇÁ¸´ç´¢º´ |
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| ¼³¸í | IDDMÀº ´ç´¢º´ÀÇ Ä¡·á¿¡ ¹Ýµå½Ã Àν¶¸°ÀÌ ÇÊ¿äÇÑ °æ¿ì¸¦ ¸»ÇÑ´Ù. ÁÖ·Î ¿øÀÎÀÌ ÀÌÀÚ¿¡ ÀÖ´Â Àν¶¸°À» ºÐºñÇÏ´Â ¼¼Æ÷ÀÇ ÆÄ±«À̸ç ÀÌ·Î ÀÎÇØ¼ ´ç´¢º´ÀÇ Ä¡·áÁ¦·Î ¾²ÀÌ´Â Àν¶¸°ÀÇ ºÐºñ¸¦ ÃËÁøÇÏ´Â ¾à¹°ÀÌ ÀÌ IDDM¿¡¼´Â ¾²ÀÏ ¼ö°¡ ¾ø°í ¿ÀÁ÷ Àν¶¸°¸¸ÀÌ Ä¡·áÁ¦·Î ¾µ ¼ö°¡ ÀÖ´Ù. ÀüÇüÀûÀÎ Àν¶¸° ÀÇÁ¸Çü ´ç´¢º´Àº ¼Ò¾Æ¿¡¼ ÈçÈ÷ ¹ß»ýÇϰí Àν¶¸° ºÐºñ¼¼Æ÷ÀÇ ÆÄ±«¿¡ ÀÇÇØ¼ Àν¶¸° ºÐºñ´ÉÀº °ÅÀÇ ¾ø´Ù. |
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| ¿µ¹® | insulin | ÇÑ±Û | Àν¶¸° |
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| ¼³¸í | ÀÌÀÚ ¶û°ÖÇѽº¼¶ÀÇ B¼¼Æ÷°¡ ÇÕ¼º-ºÐºñÇϴ ȣ¸£¸ó ´Ü¹éÁú, Æ÷µµ´çÀ» ±Û¸®ÄÚ°ÕÀ¸·Î ¹Ù²Ù´Â È£¸£¸ó´Ü¹éÁú·Î, ºÐÀÚ·®Àº 5,807ÀÌ´Ù. Ç÷ÁßÀÇ ´ç³óµµ »ó½ÂÀ¸·Î ÀÎÇÏ¿© ºÐºñ°¡ ÃËÁøµÈ´Ù. ±ÙÀ°-Áö¹æÁ¶Á÷-°£ µî Ç¥Àû¼¼Æ÷ÀÇ ¼ö¿ëü ´Ü¹éÁú°ú °áÇÕÇÏ¿© Á¤º¸¸¦ ¼¼Æ÷³»·Î Àü´ÞÇÔÀ¸·Î½á Ç÷¾× Áß¿¡¼ ´ç, ÁöÁú, ¾Æ¹Ì³ë»ê ´ë»ç¸¦ Á¶ÀýÇÑ´Ù. ´çÀÇ Á¶Á÷¿¡ ¹Þ¾Æµå¸®´Â °ÍÀ» ÃËÁøÇÏ¿© Ç÷´çÀ» ÀúÇϽÃŲ´Ù. »ý¼º-ºÐºñ·® ÀúÇÏ, Á¶Á÷¼¼Æ÷ÀÇ ¼ö¿ëü ºÎÁ·Àº °íÇ÷´çÀÇ ¿øÀÎÀÌ µÈ´Ù. ¶ÇÇÑ ¾Æ¹Ì³ë»êÀÇ Èí¼ö¿Í ´Ü¹éÁú, Áö¹æÀÇ ÇÕ¼ºÀ» ÃËÁøÇϸç Áö¹æºÐÇØ´Â ¾ïÁ¦ÇÑ´Ù. Àν¶¸°Àº ÀÌÀÚȰ¼º¼ººÐÀÇ ¾àǰÀ¸·Î¼ ´ç´¢º´ ¹× ±âŸ ÁúȯÀÇ Ä¡·á¿¡ »ç¿ëµÈ´Ù. Àν¶¸°À̶ó´Â ¸íĪÀº ¼¶À̶õ ¶æÀÇ ¶óƾ¾îÀÎ insula¿¡¼ ¿¬À¯ÇÑ´Ù. 1921³â ij³ª´ÙÀÇ ÀÇ»ç F.G. ¹êÆÃ°ú C.H. º£½ºÆ®¿¡ ÀÇÇÏ¿© óÀ½À¸·Î ÀÌÀÚ¿¡¼ äÃëµÇ¾ú°í, ±× ÈÄ Àν¶¸°ÀÇ °áÁ¤À» ¾ò°Ô µÇ¾ú´Ù. F. »ý°Å¿¡ ÀÇÇØ¼ ¼ÒÀÇ Àν¶¸°ÀÇ ±¸Á¶°¡ ¹àÇôÁ³´Âµ¥(1955), À̰ÍÀº ´Ü¹éÁú Áß¿¡¼´Â ÃÖÃÊ·Î ±¸Á¶½ÄÀÌ ¹àÇôÁø °ÍÀÌ´Ù. Æ÷µµ´çÀ¸·ÎºÎÅÍ ±Û¸®ÄÚ°ÕÀÇ »ý¼º, Æ÷µµ´çÀÇ »êÈ ¹× Áö¹æÀ¸·ÎÀÇ ÀüÈ µîÀ» ÃËÁøÇÏ´Â ÀÛ¿ëÀÌ ÀÖ´Ù. µû¶ó¼ Àν¶¸°ÀÇ ¼ö¿ë¾×À» ÁÖ»çÇϸé Ç÷´çÀÌ ÀúÇÏÇϹǷΠ´ç´¢º´ÀÇ Ä¡·á¿¡ ¾²ÀδÙ. ¶Ç Àν¶¸°À» ÇÇÇÏ¿¡ ´ë·® ÁÖ»çÇϸé È¥¼ö¿¡ ºüÁö´Â °ÍÀ» ÀÌ¿ëÇÏ¿© Á¤½Åº´ Ä¡·á¿¡ Àν¶¸°¼îÅ©¿ä¹ýÀ¸·Î¼ ¾²ÀδÙ. |
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| ¿µ¹® | childhood diabetes | ÇÑ±Û | ¼Ò¾Æ´ç´¢º´ |
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| ¼³¸í | ¼Ò¾Æ¿¡ ³ªÅ¸³ª´Â ´ç´¢º´. ´ç´¢º´Àº Àν¶¸° ºÎÁ·À¸·Î ü³» Æ÷µµ´ç ÀÌ¿ëÀÌ ÀúÇϵǾî ź¼öȹ°-Áö¹æ-´Ü¹éÁú ´ë»ç°¡ ÀåÇØ¸¦ ÀÏÀ¸Å°´Â Áúº´À¸·Î, ¼ºÀÎÇü ´ç´¢º´°ú ¿¬¼ÒÇü ´ç´¢º´ÀÌ ÀÖ´Ù. ¼ºÀÎÇüÀº Àν¶¸°ÀÇ »ó´ëÀû ºÎÁ·, Áï ºñ¸¸À¸·Î ÀÎÇÑ Àν¶¸° °¨¼ö¼ºÀÇ ÀúÇÏ °á°ú Àν¶¸° Çʿ䷮ÀÇ Áõ´ë¿¡¼ ¿À´Â °ÍÀ̸ç, ¼Ò¾ÆÇü ´ç´¢º´Àº ÀÌÀÚÀÇ ¶û°Ô¸£Çѽº¼¶ º£Å¸(¥â)¼¼Æ÷ÀÇ ÀåÇØ·Î ÀÎÇÑ Àν¶¸°ÀÇ Àý´ëÀû °áÇÌ¿¡¼ ¿Â´Ù. ¼¼°èº¸°Ç±â±¸(WHO)ÀÇ ±ÇÀåÀ¸·Î 15¼¼ ÀÌÀü¿¡ ¹ßº´ÇÏ´Â ´ç´¢º´À» ¸ðµÎ ¼Ò¾Æ´ç´¢º´À̶ó Çϴµ¥, ¾î¸°ÀÌ¿¡°Ôµµ °£È¤ ¼ºÀÎÇü(¶Ç´Â ºñ¸¸Çü) ´ç´¢º´ÀÌ ÀÖÀ¸¹Ç·Î ¼Ò¾Æ´ç´¢º´À̶ó ÇÔÀº ¼Ò¾Æ±â¿¡ ¹ßº´ÇÏ´Â ¼Ò¾ÆÇü°ú ¼ºÀÎÇü ´ç´¢º´ÀÇ ÃÑĪÀ̶ó ÇÒ ¼ö ÀÖ´Ù. ÇöÀç±îÁö Åë°è¿¡ ÀÇÇϸé ÀüüÀα¸ÀÇ ¾à 5%´Â ´ç´¢º´À» °¡Áö°í ÀÖÀ¸¸ç, ±× °¡¿îµ¥ ¾à 2%°¡ 15¼¼ ÀÌÀü¿¡ ¹ßº´ÇÏ´Â °ÍÀ¸·Î ¾Ë·ÁÁ³´Ù. |
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| ¿µ¹® | diabetes insipidus | ÇÑ±Û | ¿äºØÁõ |
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| ¼³¸í | 1ÀÏ ¼Òº¯ÀÇ ¾çÀÌ 4~15¸®ÅÍ·Î º´ÀûÀ¸·Î Áõ°¡ÇÏ´Â »óÅÂ. ÀÌ Áõ»óÀº ³úÀÇ ¹Ù´Ú¿¡ ºÙ¾î Àִ ȣ¸£¸óÀ» ÁÖ·Î ºÐºñÇÏ´Â ÀÛÀº ±â°üÀÎ ³úÇϼöü ÈÄ¿±¿¡¼ ºÐºñµÇ¾î ¼öºÐÀÇ Èí¼ö¸¦ ÃËÁøÇÏ¿© ü³»¿¡ ¼öºÐÀÇ ¾çÀ» ´ÃÀÌ´Â ¿ªÇÒÀ» ÇÏ°í µ¿½Ã¿¡ Ç÷°üÀ» ¼öÃà½ÃŰ´Â ÀÛ¿ëÀÌ ÀÖ¾î Ç÷¾ÐÀ» »ó½Â½ÃŰ´Â ¿ªÇÒµµ ÇÏ´Â ADH(Ç×ÀÌ´¢È£¸£¸ó)ÀÇ ºÎÁ·¿¡ ÀÇÇÑ´Ù. ADH°¡ ºÎÁ·µÉ °æ¿ì¿¡´Â ÄáÆÏ¿¡¼ ¼öºÐÀÇ Èí¼ö°¡ ÀϾÁö ¾Ê¾Æ¼ ¸¹Àº ¾çÀÇ ¼öºÐÀÌ ½ÅÀåÀ» ÅëÇØ °É·¯Á®¼ ¼Òº¯À¸·Î ³ª¿À°Ô µÈ´Ù. |
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| CDI | cell-directed inhibitor; central or chronic diabetes insipidus; Children's Depression Inventory; col... |
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| IDDM | Insulin Dependent Diabetes Mellitus = Type I DM |
| NIDDM | Non-Insulin Dependent Diabetes Mellitus = Type II DM |
| IDD | insulin-dependent diabetes; intraluminal duodenal diverticulum; Inventory to Diagnose Depression |
| IDDM | insulin-dependent diabetes mellitus |
| IDDM | I-insulin-dependent diabetes mellitus |
|---|---|
| IDDM | Insulin Dependent Diabetes |
| IDD | Insulin dependent diabetes |
| NIDDM | Non Insulin Dependent Diabetes Mellitus |
| NIDD | Non-insulin dependent diabetes |
IGF-II : insulin like growth factor-IIÀÇ ¾àÀÚ. ¸¹Àº Àå±â¿Í Á¶Á÷¿¡ ÀÛ¿ëÇÏ¿© ´Ü¹é ÇÕ¼º°ú DNA, RNAÀÇ ÇÕ¼ºÀ» Áõ°¡½ÃÄÑ ¼¼Æ÷ÀÇ ¼ö¿Í ¾çÀ» Áõ°¡
| insulin dependent diabetes | A form of diabetes that requires the daily injection of the hormone insulin to maintain normal body chemistry. Avoidance of insulin in these patients will result in a severe metabolic derangement known as diabetic ketoacidosis. (27 Sep 1997) |
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| non-insulin-dependent diabetes mellitus | <disease> An often mild form of diabetes mellitus of gradual onset, usually in obese individuals over age 35; absolute plasma insulin levels are normal to high, but relatively low in relation to plasma glucose levels; ketoacidosis is rare, but hyperosmolar coma can occur; responds well to dietary regulation and/or oral hypoglycaemic agents, but diabetic complications and degenerative changes can develop. (05 Mar 2000) |
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| diabetes mellitus, insulin-dependent | Diabetes mellitus characterised by insulin deficiency, sudden onset, severe hyperglycaemia, rapid progression to ketoacidosis, and death unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. (12 Dec 1998) |
| diabetes mellitus, non-insulin-dependent | Diabetes characterised by the ability to survive without ketoacidosis in the absence of insulin therapy. It is usually of slow onset and patients exhibit a tendency to obesity. (12 Dec 1998) |
| insulin-dependent diabetes mellitus | A chronic condition in which the pancreas makes little or no insulin because the beta cells have been destroyed. The body is then not able to use the glucose (blood sugar) for energy. IDDM usually comes on abruptly, although the damage to the beta cells may begin much earlier. The signs of IDDM are a great thirst, hunger, a need to urinate often, and loss of weight. To treat the disease, the person must inject insulin, follow a diet plan, exercise daily, and test blood glucose several times a day. IDDM usually occurs in children and adults who are under age 30. This type of diabetes used to be known as juvenile diabetes, juvenile-onset diabetes, and ketosis-prone diabetes. (09 Oct 1997) |
| aid to families with dependent children | Financial assistance provided by the government to indigent families with dependent children who meet certain requirements as defined by the social security act, title IV, in the u.s. (12 Dec 1998) |
| androgen-dependent secretory protease | <enzyme> Glycoprotein from dog prostate; hydrolyzes arginine and lysine-containing amide and ester protease substrates Registry number: EC 3.4.99.- Synonym: ads-protease (26 Jun 1999) |
| antibody-dependent cell cytotoxicity | The phenomenon of antibody-mediated target cell destruction by non-sensitised effector cells. The identity of the target cell varies, but it must possess surface IgG whose fc portion is intact. The effector cell is a "killer" cell possessing fc receptors. It may be a lymphocyte lacking conventional b- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent. (12 Dec 1998) |
| antibody-dependent enhancement | Enhancement of viral infectivity caused by non-neutralizing antibodies. There are at least two mechanisms known to account for this: mediation by fc receptors (receptors, fc) or by complement receptors (receptors, complement). Either the virus is complexed with antiviral IgG and binds to fc receptors, or virus is coated with antiviral IgM and binds to complement receptors. (12 Dec 1998) |
| aromatic NADH-dependent nitroreductase | <enzyme> See also record for 1-nitroreductase; type I nitroreductase is not inhibited by oxygen Registry number: EC 1.- Synonym: nitrofuran reductase, nitrofurazone reductase, type I nitroreductases, NADH-dependent nitro reductase, nitrofurantoin reductase, p-dinitrobenzene reductase, benznidazole nitroreductase, nifurtimox nitroreductase, oxygen-insensitive NADPH nitroreductase, nitrobenzene nitroreductase (26 Jun 1999) |
| aspartic acid 2-oxoglutarate-dependent dioxygenase | <enzyme> Hydroxylates one aspartic acid residue in the first egf-like unit of factor ix Registry number: EC 1.14.11.- Synonym: aspartate 2-oxoglutarate dioxygenase, asp-2-og-dioxygenase, aspartyl beta-hydroxylase, aspartyl (asparaginyl) beta-hydroxylase (26 Jun 1999) |
| ATP dependent 26S protease | <enzyme> Degrades proteins conjugated to ubiquitin; composed of cf-1,cf-2, and cf-3; cf-2 (also known as 240-kD proteasome inhibitor) is identical to aminolevulinic acid dehydratase Registry number: EC 3.4.99.- Synonym: 26s protease, 26 s proteasome complex, 26s proteasome (26 Jun 1999) |
| ATP-dependent DNA strand transferase | <enzyme> From human cell nuclei; catalyses strand exchange between homologous DNA sequences; magnesium dependent, requires ATP hydrolysis Registry number: EC 2.7.7.- Synonym: ATP-dep-DNA-str trnsfase (26 Jun 1999) |
| ATP-ubiquitin-dependent proteinase | <enzyme> A component of the cytosolic ubiquitin-dependent proteolysis system Registry number: EC 3.4.- Synonym: ucden (26 Jun 1999) |
| autophosphorylation-dependent multifunctional protein kinase | <enzyme> A camp/ca(2+)-independent protein kinase; phosphorylates and activates phosphorylase b kinase; phosphorylates and inactivates glycogen synthase Registry number: EC 2.7.1.- Synonym: auto-kinase (26 Jun 1999) |
| calcium-calmodulin-dependent phosphodiesterase | <enzyme> Hydrolyzes both cgmp and camp; induced during mitogenesis Registry number: EC 3.1.4.- Synonym: ca-cam-phosphodiesterase, calmodulin-dependent cgmp phosphodiesterase (26 Jun 1999) |
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