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"insulin activating factor"¿¡ ´ëÇÑ °Ë»ö °á°úÀÔ´Ï´Ù. °Ë»ö °á°ú º¸´Â µµÁß¿¡ Tab ۸¦ ´©¸£½Ã¸é °Ë»ö âÀÌ ¼±Åõ˴ϴÙ.
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¿µ¹® insulin ÇÑ±Û Àν¶¸°
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  ÀÌÀÚ ¶û°ÖÇѽº¼¶ÀÇ B¼¼Æ÷°¡ ÇÕ¼º-ºÐºñÇϴ ȣ¸£¸ó ´Ü¹éÁú, Æ÷µµ´çÀ» ±Û¸®ÄÚ°ÕÀ¸·Î ¹Ù²Ù´Â È£¸£¸ó´Ü¹éÁú·Î, ºÐÀÚ·®Àº 5,807ÀÌ´Ù. Ç÷ÁßÀÇ ´ç³óµµ »ó½ÂÀ¸·Î ÀÎÇÏ¿© ºÐºñ°¡ ÃËÁøµÈ´Ù. ±ÙÀ°-Áö¹æÁ¶Á÷-°£ µî Ç¥Àû¼¼Æ÷ÀÇ ¼ö¿ëü ´Ü¹éÁú°ú °áÇÕÇÏ¿© Á¤º¸¸¦ ¼¼Æ÷³»·Î Àü´ÞÇÔÀ¸·Î½á Ç÷¾× Áß¿¡¼­ ´ç, ÁöÁú, ¾Æ¹Ì³ë»ê ´ë»ç¸¦ Á¶ÀýÇÑ´Ù. ´çÀÇ Á¶Á÷¿¡ ¹Þ¾Æµå¸®´Â °ÍÀ» ÃËÁøÇÏ¿© Ç÷´çÀ» ÀúÇϽÃŲ´Ù. »ý¼º-ºÐºñ·® ÀúÇÏ, Á¶Á÷¼¼Æ÷ÀÇ ¼ö¿ëü ºÎÁ·Àº °íÇ÷´çÀÇ ¿øÀÎÀÌ µÈ´Ù. ¶ÇÇÑ ¾Æ¹Ì³ë»êÀÇ Èí¼ö¿Í ´Ü¹éÁú, Áö¹æÀÇ ÇÕ¼ºÀ» ÃËÁøÇϸç Áö¹æºÐÇØ´Â ¾ïÁ¦ÇÑ´Ù. Àν¶¸°Àº ÀÌÀÚȰ¼º¼ººÐÀÇ ¾àǰÀ¸·Î¼­ ´ç´¢º´ ¹× ±âŸ ÁúȯÀÇ Ä¡·á¿¡ »ç¿ëµÈ´Ù. Àν¶¸°À̶ó´Â ¸íĪÀº ¼¶À̶õ ¶æÀÇ ¶óƾ¾îÀΠinsula¿¡¼­ ¿¬À¯ÇÑ´Ù. 1921³â Ä³³ª´ÙÀÇ ÀÇ»ç F.G. ¹êÆÃ°ú C.H. º£½ºÆ®¿¡ ÀÇÇÏ¿© Ã³À½À¸·Î ÀÌÀÚ¿¡¼­ Ã¤ÃëµÇ¾ú°í, ±× ÈÄ Àν¶¸°ÀÇ °áÁ¤À» ¾ò°Ô µÇ¾ú´Ù. F. »ý°Å¿¡ ÀÇÇØ¼­ ¼ÒÀÇ Àν¶¸°ÀÇ ±¸Á¶°¡ ¹àÇôÁ³´Âµ¥(1955), À̰ÍÀº ´Ü¹éÁú Áß¿¡¼­´Â ÃÖÃʷΠ±¸Á¶½ÄÀÌ ¹àÇôÁø °ÍÀÌ´Ù. Æ÷µµ´çÀ¸·ÎºÎÅÍ ±Û¸®ÄÚ°ÕÀÇ »ý¼º, Æ÷µµ´çÀÇ »êÈ­ ¹× Áö¹æÀ¸·ÎÀÇ ÀüÈ­ µîÀ» ÃËÁøÇϴ ÀÛ¿ëÀÌ ÀÖ´Ù. µû¶ó¼­ Àν¶¸°ÀÇ ¼ö¿ë¾×À» ÁÖ»çÇϸé Ç÷´çÀÌ ÀúÇÏÇϹǷΠ´ç´¢º´ÀÇ Ä¡·á¿¡ ¾²ÀδÙ. ¶Ç Àν¶¸°À» ÇÇÇÏ¿¡ ´ë·® ÁÖ»çÇϸé È¥¼ö¿¡ ºüÁö´Â °ÍÀ» ÀÌ¿ëÇÏ¿© Á¤½Åº´ Ä¡·á¿¡ Àν¶¸°¼îÅ©¿ä¹ýÀ¸·Î¼­ ¾²ÀδÙ.
  
  
¿µ¹® IDDM(Insulin-Dependent Diabetes Mellitus) ÇÑ±Û Àν¶¸°ÀÇÁ¸´ç´¢º´
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  IDDMÀº ´ç´¢º´ÀÇ Ä¡·á¿¡ ¹Ýµå½Ã Àν¶¸°ÀÌ ÇÊ¿äÇÑ °æ¿ì¸¦ ¸»ÇÑ´Ù. ÁַΠ¿øÀÎÀÌ ÀÌÀÚ¿¡ Àִ Àν¶¸°À» ºÐºñÇϴ ¼¼Æ÷ÀÇ ÆÄ±«À̸ç À̷ΠÀÎÇØ¼­ ´ç´¢º´ÀÇ Ä¡·áÁ¦·Î ¾²À̴ Àν¶¸°ÀÇ ºÐºñ¸¦ ÃËÁøÇϴ ¾à¹°ÀÌ ÀÌ IDDM¿¡¼­´Â ¾²ÀÏ ¼ö°¡ ¾ø°í ¿ÀÁ÷ Àν¶¸°¸¸ÀÌ Ä¡·áÁ¦·Î ¾µ ¼ö°¡ ÀÖ´Ù. ÀüÇüÀûÀΠÀν¶¸° ÀÇÁ¸Çü ´ç´¢º´Àº ¼Ò¾Æ¿¡¼­ ÈçÈ÷ ¹ß»ýÇϰí Àν¶¸° ºÐºñ¼¼Æ÷ÀÇ ÆÄ±«¿¡ ÀÇÇØ¼­ Àν¶¸° ºÐºñ´ÉÀº °ÅÀÇ ¾ø´Ù.
¿µ¹® rheumatoid factor ÇÑ±Û ·ù¸¶Æ¼½º ÀÎÀÚ
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  IgGÀÇ FcºÎÀ§¿¡ Àִ Ç׿ø°áÁ¤ÀÎÀÚ¿¡ ´ëÇÑ Ç×ü·Î¼­ ÀüÇüÀûÀΠ¶Ç´Â È®½ÇÇÑ ·ù¸¶Æ¼½º°üÀý¿°(rheumatoid arthritis) È¯ÀÚÀÇ 80%¿¡¼­ ¹ß°ßµÈ´Ù. ·ù¸¶Æ¼½º ÀÎÀڴ IgM, IgG, IgAÁß Çϳª°¡ µÉ ¼ö ÀÖÀ¸³ª ÁַΠIgMÀÌ´Ù. ¼Ò¾Æ·ù¸¶Æ¼½º°üÀý¿°(juvenile rheumatoid arthritis: ¼Ò¾Æ±â¿¡ ¹ß»ýÇϴ ·ù¸¶Æ¼½º°üÀý¿°)À» ºñ·ÔÇÑ, ´Ù¸¥ °áÇÕÁ¶Á÷º´À̳ª °¨¿°º´¿¡µµ ³ªÅ¸³¯ ¼ö ÀÖ´Ù
¿µ¹® growth factor ÇÑ±Û ¼ºÀåÀÎÀÚ
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  ¼¼Æ÷ÀÇ ºÐÈ­ ¹× ¼ºÀå¿¡ °ü¿©Çϴ ´Ü¹éÁú. ¼ºÀåÀÎÀڴ Á¤»ó ¼¼Æ÷Áֱ⿡ ÇʼöÀûÀ̱⠶§¹®¿¡ µ¿¹°ÀÇ »ý¸í¿¡ Áß´ëÇÑ ¿ä¼Ò°¡ µÈ´Ù. ¹«¾ùº¸´Ùµµ ¼ºÀåÀÎÀڴ Å¾ÆÀÇ ¹ßÀ°À» Á¶Á¤Çϰí Á¶Á÷ÀÇ À¯Áö ¹× º¸¼ö¿¡ Áß´ëÇÑ ¿ªÇÒÀ» Çϸç, Ç÷±¸ÀÇ »ý¼ºÀ» ÀÚ±ØÇÑ´Ù. ¶ÇÇÑ ¾ÏÀÇ ÁøÇà°úÁ¤¿¡µµ °ü¿©ÇÑ´Ù.
¿µ¹® risk factor ÇÑ±Û À§ÇèÀÎÀÚ
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  • ¿µ¹®
    ÇѱÛ
  • conglutinogen activating factor
    ±³Âø¿øÈ°¼ºÀÎÀÚ
  • lymphocyte activating factor
    ¸²ÇÁ±¸È°¼ºÀÎÀÚ
  • macrophage-activating factor
    Å«Æ÷½Ä¼¼Æ÷Ȱ¼ºÀÎÀÚ, ´ë½Ä¼¼Æ÷Ȱ¼ºÀÎÀÚ
  • platelet activating factor
    Ç÷¼ÒÆÇȰ¼ºÀÎÀÚ
  • insulin-like growth factor
    Àν¶¸°À¯»ç¼ºÀåÀÎÀÚ
  • lymphocyte-activating determinant
    ¸²ÇÁ±¸È°¼º°áÁ¤ÀÎÀÚ
  • crystalline insulin
    °áÁ¤Àν¶¸°
  • depot insulin
    ÀúÀåÀν¶¸°
  • fast-acting insulin
    ±Þ¼ÓÀÛ¿ëÀν¶¸°
  • immunoreactive insulin
    ¸é¿ª¹ÝÀÀÀν¶¸°
  • insulin
    Àν¶¸°
  • insulin clamp
    Àν¶¸°Å¬·¥ÇÁ
  • insulin receptor
    Àν¶¸°¼ö¿ëü
  • insulin receptor substrate-1
    Àν¶¸°¼ö¿ëü±âÁú-1
  • insulin resistance
    Àν¶¸°ÀúÇ×, Àν¶¸°³»¼º
´ëÇÑÀÇÇù Çʼö ÀÇÇпë¾îÁý »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • platelet activating factor
    Ç÷¼ÒÆÇȰ¼ºÀÎÀÚ
  • insulin
    Àν¶¸°
  • NPH insulin
    ¿£ÇÇ¿¡ÀÌÄ¡Àν¶¸°
  • regular insulin
    ¼ÓÈ¿Àν¶¸°, ºü¸¥ÀÛ¿ëÀν¶¸°
  • insulin resistance
    Àν¶¸°ÀúÇ×
  • factor
    ÀÎÀÚ, ¿äÀÎ, °è¼ö
  • activation factor
    Ȱ¼ºÀÎÀÚ
  • antiplatelet factor
    Ç×Ç÷¼ÒÆÇÀÎÀÚ
  • coagulation V factor
    Á¦5Ç÷¾×ÀÀ°íÀÎÀÚ
  • exclusion of confounding factor
    ±³¶õº¯¼ö¹èÁ¦
  • growth factor
    ¼ºÀåÀÎÀÚ
  • intrinsic factor
    ³»ÀÎÀÎÀÚ, ³»ÀÎÀÚ
  • nerve growth factor
    ½Å°æ¼ºÀåÀÎÀÚ
  • platelet-derived growth factor
    Ç÷¼ÒÆÇÀ¯·¡¼ºÀåÀÎÀÚ, Ç÷¼ÒÆÇ±â¿ø¼ºÀåÀÎÀÚ
  • precipitation factor
    ÃËÁø¿äÀÎ
¿¾ ´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • conglutinogen activating factor
    ±³Âø¿øÈ°¼ºÀÎÀÚ
  • lymphocyte activating factor
    ¸²ÇÁ±¸È°¼ºÀÎÀÚ
  • macrophage-activating factor
    Å«Æ÷½Ä¼¼Æ÷Ȱ¼ºÀÎÀÚ
  • platelet activating factor
    Ç÷¼ÒÆÇȰ¼ºÀÎÀÚ
  • insulin-like growth factor
    Àν¶¸°À¯»ç¼ºÀåÀÎÀÚ
  • catabolite activating protein
    ÀÌÈ­»ê¹°È°¼ºÈ­´Ü¹é
  • lymphocyte-activating determinant
    ¸²ÇÁ±¸È°¼º°áÁ¤±â
  • crystalline insulin
    °áÁ¤Àν¶¸°
  • depot insulin
    ÀúÀåÀν¶¸°
  • insulin-dependent diabetes
    Àν¶¸°ÀÇÁ¸´ç´¢º´
  • insulin-resistant diabetes
    Àν¶¸°ÀúÇ×´ç´¢º´
  • non-insulin-dependent diabetes
    ºñÀν¶¸°ÀÇÁ¸´ç´¢º´
  • glucose insulin tolerance test
    Æ÷µµ´çÀν¶¸°°ßµõ°Ë»ç
  • insulin-induced hypoglycemia
    Àν¶¸°À¯µµÀúÇ÷´ç(Áõ)
  • insulin
    Àν¶¸°
¿¾ ´ëÇÑÀÇÇù 2 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • PAF =platelet activating factor
    Ç÷¼ÒÆÇȰ¼ºÀÎÀÚ.
  • PAF= platelet activating factor
    Ç÷¼ÒÆÇ Ȱ¼ºÀÎÀÚ.
  • T cell activating factor
    T¼¼Æ÷Ȱ¼ºÀÎÀÚ
  • platelet activating factor
    Ç÷¼ÒÆÇ Ȱ¼º ÀÎÀÚ
  • platelet-activating factor (PAF)
    Ç÷¼ÒÆÇ Ȱ¼ºÈ­ÀÎÀÚ
  • platelet-activating factor (paf)
    Ç÷¼ÒÆÇȰ¼ºÈ­ÀÎÀÚ(úìá³÷ùüÀàõûùì×í­)
  • IGF-I(insulin-like growth factor-I)
    Àν¶¸° À¯»ç ¼ºÀåÀÎÀÚ-1
  • General anesthesia, reticular activating system and.
    Àü½Å¸¶Ãë(îïãóئö­), ¸Á»óüȰ¼ºÈ­°è(ØÑßÒô÷üÀàõûùͧ)
  • guanosine triphosphate-activating protein
    »ïÀλ걸¾Æ³ë½Å Ȱ¼º´Ü¹éÁú
  • F factor (fertility factor)
    FÀÎÀÚ, ¼öÅÂÀÎÀÚ
  • Insulin
    Àν¶¸°
  • Insulin shock
    Àν¶¸°¼ï
  • Insulin-like growth factors
    Àν¶¸°¾ç(å×)¼ºÀå(à÷íþ)È£¸£¸ó
  • anti-insulin
    Ç×Àν¶¸°.
  • arginine-insulin test
    ¾Æ¸£±â´Ñ-Àν¶¸°½ÃÇè
¿¾ ´ëÇÑÀÇÇù 3 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • conglutinogen activating factor
    ±³Âø¿ø (conglutinogen, factor IÀÇ ¿¾¸»)
  • lymphocyte activating factor
    ¸²ÇÁ±¸È°¼ºÀÎÀÚ
  • lymphocyte activating factor (LAF)
    ¸²ÇÁ±¸ Ȱ¼ºÈ­ÀÎÀÚ
  • macrophage activating factor (MAF)
    ´ë½Ä¼¼Æ÷ Ȱ¼ºÀÎÀÚ
  • macrophage chemotactic and activating factor
    ´ë½Ä¼¼Æ÷ ÁÖÈ­ ¹× Ȱ¼º ÀÎÀÚ
  • paf(platelet activating factor)
    Ç÷¼ÒÆÇȰ¼ºÀÎÀÚ(úìá³÷ù üÀàõì×í­)
  • platelet activating factor
    Ç÷¼ÒÆÇ Ȱ¼º ÀÎÀÚ
  • platelet-activating factor (PAF)
    Ç÷¼ÒÆÇ Ȱ¼ºÈ­ÀÎÀÚ
  • platelet-activating factor (paf)
    Ç÷¼ÒÆÇȰ¼ºÈ­ÀÎÀÚ(úìá³÷ùüÀàõûùì×í­)
  • insulin-like growth factor
    Àν¶¸°À¯»ç¼ºÀåÀÎÀÚ
  • catabolite activating protein
    ÀÌÈ­»ê¹° Ȱ¼ºÈ­´Ü¹éÁú
  • descending reticular activating system
    ÇÏÇ༺ ¸Á»óȰ¼º°è(ù»ú¼àõ ØÑßÒüÀàõͧ)
  • guanosine triphosphate-activating protein
    »ïÀλ걸¾Æ³ë½Å Ȱ¼º´Ü¹éÁú
  • lymphocyte-activating determinant
    ¸²ÇÁ±¸È°¼º °áÁ¤±â
  • reticular activating system
    ¸Á»óüȰ¼ºÈ­°è, ¸Á»óȰ¼º°è.
´ëÇÑÇØºÎÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • Beta cell [Insulin cell]
    º£Å¸¼¼Æ÷ [Àν´¸°¼¼Æ÷]
    [¿¾ ¿ë¾î] º£Å¸¼¼Æ÷
´ëÇѱâ»ýÃæÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • Duffy factor
    ´õÇÇÀÎÀÚ
´ëÇÑ»ýÈ­ÇкÐÀÚ»ý¹°ÇÐȸ ¿ë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • platelet-activating factor
    Ç÷¼ÒÆÇȰ¼º ÀÎÀÚ(úìá³÷ùüÀàõì×í­)
  • activating enzyme
    "ºÎȰȿ¼Ò (Ý·üÀý£áÈ), Ȱ¼ºÈ­È¿¼Ò (üÀàõûùý£áÈ)"
  • acyl activating enzyme
    ¾Æ½ÇºÎȰȿ¼Ò (Ý·üÀý£áÈ)
  • amino acid activating enzyme
    ¾Æ¹Ì³ë»ê(ß«) Ȱ¼ºÈ­(üÀàõûù) È¿¼Ò(ý£áÈ)
  • fatty acid activating enzyme
    Áö¹æ»ê Ȱ¼ºÈ­ È¿¼Ò (ò·Û¸ß«üÀàõûùý£áÈ)
  • anti-insulin
    Ç×(ù÷)Àν¶¸°
  • atypical insulin
    ºñÁ¤Çü (ÞªïÒúþ)Àν¶¸°
  • bound insulin
    °áÇÕ(Ì¿ùê)Àν¶¸°
  • desalanine insulin
    ¾Ë¶ó´ÑÁ¦°Å(ð¶ËÛ)Àν¶¸°
  • free insulin
    À¯¸®(ë´×î) Àν¶¸°
  • globin zinc insulin
    ±Û·Îºó ¾Æ¿¬(䬿ç)Àν¶¸°
  • immunoreactive insulin
    ¸é¿ª¹ÝÀÀ¼º(Øóæ¹Úãëëàõ) Àν¶¸°
  • insulin
    Àν¶¸°
  • insulin resistance index
    Àν¶¸° ÀúÇ×Áö¼ö(î½ù÷ò¦â¦)
  • insulin shock
    Àν¶¸° ¼ï
KI ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 10 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • insulin
    Àν¶¸°
  • insulin dependent diabetes mellitus
    Àν¶¸°ÀÇÁ¸¼º´ç´¢º´
  • attenuation factor
    °¨¾à¿ä¼Ò, °¨¼è¿äÀÎ
  • conversion factor
    º¯È¯ÀÎÀÚ
  • factor
    ÀÎÀÚ
  • predisposing factor
    ¼ÒÀÎ, Áúº´¼ÒÁú
  • Q factor
    Å¥ÀÎÀÚ
  • rheumatoid factor
    ·ù¸¶Æ¼½º¾çÀÎÀÚ
  • risk factor
    À§Çè¿äÀÎ
  • turbo factor
    Åͺ¸ÀÎÀÚ
KMLE ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
PAF paroxysmal atrial fibrillation; peroxisomal assembly factor; phosphodiesterase-activating factor; pl...
KAF conglutinogen-activating factor; killer-assisting factor; kinase activating factor
CF calcaneal fibular [ligament]; calcium leucovorin; calf blood flow; calibration factor; cancer-free; ...
LAF laminar air flow; Latin American female; leukocyte-activating factor; lymphocyte-activating factor
EF ectopic focus; edema factor; ejection fraction; elastic fibril; electric field; elongation factor; e...
KMLE ÀÚµ¿ÃßÃâ ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
ATF Activating Transcription Factor
ATF1 Activating transcription factor 1
ATF2 Activating transcription factor 2
APAF-1 Apoptotic protease activating factor-1
ATF CRE)/activating transcription factor
°æºÏ´ë Ä¡°ú´ëÇÐ ±¸°­³»°ú ±³½Ç »çÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
    ¼³¸í
  • IGF-I : insulin like growth factor-IÀÇ ¾àÀÚ. ¼ºÀåÆÇÀÎ epiphyseal plate¿¡ ¿¬°ñ »ý¼ºÀ» Áõ°¡½ÃÄÑ »ÀÀÇ ¼ºÀåÀ» ÃËÁøÇÑ´Ù.

    IGF-II : insulin like growth factor-IIÀÇ ¾àÀÚ. ¸¹Àº Àå±â¿Í Á¶Á÷¿¡ ÀÛ¿ëÇÏ¿© ´Ü¹é ÇÕ¼º°ú DNA, RNAÀÇ ÇÕ¼ºÀ» Áõ°¡½ÃÄÑ ¼¼Æ÷ÀÇ ¼ö¿Í ¾çÀ» Áõ°¡

    Àν¶¸°¾ç ¼ºÀå ÀÎÀÚ °áÇÕ ´Ü¹éÁú
    insulinelike growth factor binding
  • macrophage activating factor
    ´ë½Ä ¼¼Æ÷ Ȱ¼º ÀÎÀÚ
  • platelet-activating factor
    Ç÷¼ÒÆÇ Ȱ¼º ÀÎÀÚ
  • reticular activating formation
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  • arginine-insulin test
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  • insulin dependent diabetes mellitus
    Àν¶¸° ÀÇÁ¸¼º ´ç´¢º´
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CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
insulin activating factor <chemical> Activates insulin gene transcription in pancreatic beta cells.
Synonym: insaf
(05 Dec 1998)
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
macrophage-activating factor An agent that stimulates macrophages to attack and ingest cancer cells. They are secreted by stimulated lymphocytes that prime macrophages to become non-specifically cytotoxic to tumours.
They also modulate the expression of macrophage cell surface ia antigens. One maf is interferon-gamma (interferon type II). Other factors antigenically distinct from ifn-gamma have also been identified.
(12 Dec 1998)
monocyte chemotactic and activating factor Cytokine of the C C subfamily, co induced with IL-8 on stimulation of endothelial cells, fibroblasts or monocytes that activates and is chemotactic for, monocytes. A chemokine.
(18 Nov 1997)
platelet-activating factor <cytokine> Potent phospholipid activator and mediator of many leucocyte functions, including platelet aggregation, inflammation, and anaphylaxis.
It is produced in response to specific stimuli by a variety of cell types, including neutrophils, basophils, platelets, and endothelial cells. Several molecular species of platelet-activating factor have been identified which vary in the length of the O-alkyl side chain. It is an important mediator of bronchoconstriction.
Synonym: platelet-aggregating factor.
Acronym: PAF
(20 Sep 2002)
neutrophil activating factor <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes.
It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4.
Acronym: IL-8
(12 Dec 1998)
osteoclast activating factor A lymphokine that stimulates bone resorption and inhibits bone-collagen synthesis.
(05 Mar 2000)
receptors, insulin-like-growth factor I Specific proteins on or in cells to which insulin-like growth factor I (somatomedin c) binds and thereby modifies the function of the cells. These receptors contain transmembrane and cytosolic domains, bind igf-I preferentially, and have high-affinity sites for igf-II. The alpha-subunit has a mw of 130 kD and the beta subunit possesses tyrosine kinase activity.
(12 Dec 1998)
receptors, insulin-like-growth-factor II Specific proteins on or in cells to which insulin-like growth factor II and mannose-6-phosphate bind and thereby modify the function of the cells. These receptors have a mw of 250 kD and possess no tyrosine kinase activity.
(12 Dec 1998)
insulin-antagonizing factor A principle in extracts of the anterior lobe of the hypophysis that raises the blood sugar and antagonises the action of insulin; purified pituitary growth hormone produces an identical effect.
Synonym: insulin-antagonizing factor.
(05 Mar 2000)
insulin like growth factor <growth factor> Insulin like growth factors I and II are polypeptides with considerable sequence similarity to insulin.
They are capable of eliciting the same biological responses, including mitogenesis in cell culture. On the cell surface, there are two types of insulin like growth factor receptor, one of which closely resembles the insulin receptor (which is also present).
Insulin like growth factor I = somatomedin A = somatomedin C
Insulin like growth factor II = MSA (Multiplication stimulating activity).
Insulin like growth factor 1 is released from the liver in response to growth hormone.
Acronym: IGF
(18 Nov 1997)
insulin-like growth-factor binding protein 1 One of the six homologous proteins that specifically bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits igf binding to cell surface receptors and thereby inhibits igf-mediated mitogenic and cell metabolic actions. (proc soc exp biol med 1993;204(1):4-29)
(12 Dec 1998)
insulin-like growth factor-binding protein 2 One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level.
(12 Dec 1998)
insulin-like growth factor binding protein 3 One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level.
(12 Dec 1998)
insulin like growth-factor-binding protein 4 One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level.
(12 Dec 1998)
insulin-like growth-factor-binding-protein 5 One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level.
(12 Dec 1998)
insulin-like-growth-factor-binding protein 6 One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level.
(12 Dec 1998)
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