| CMM | cell-mediated mutagenesis; cutaneous malignant melanoma |
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| MMM | see 3-M [syndrome]; microsome-mediated mutagenesis; myelofibrosis with myeloid metaplasia; myeloscle... |
| STM | Signature-tagged mutagenesis |
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| SDM | Site-directed mutagenesis |
| insertional mutagenesis | Generally, mutagenesis of DNA by the insertion of one or more bases. Specific examples: 1. Oncogenesis by insertion of a retrovirus adjacent to a cellular proto-oncogene. 2. A strategy of mutagenesis with transposons. After a round of transposition, progeny are screened by PCR, with transposon and gene specific primers, for the proximity of the transposon sequence to the gene of interest. As PCR can only produce products up to 1-2 kb, a large fraction of progeny identified as positive by PCR will have a transposon close enough to the gene to inactivate or otherwise alter its pattern of expression. (18 Nov 1997) |
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| mutagenesis, insertional | Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA can be inserted into or adjacent to a cellular proto-oncogene. Insertion of the provirus can cause mutations by interrupting coding sequences or regulatory elements, or cause unregulated expression of the proto-oncogene resulting in tumour formation. (12 Dec 1998) |
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| insertional inactivation | The inactivation of a gene due to the insertion of exogenous genetic material into that gene. (14 Nov 1997) |
| cassette mutagenesis | The production of mutants within a region (often bounded by unique restriction sites) by the use of synthetic oligonucleotides that fill the gap with mutants designed into the synthetic genetic material. (05 Mar 2000) |
| mutagenesis | The development of mutations. (09 Oct 1997) |
| mutagenesis, site-directed | Mutagenesis where the mutation is caused by in vitro induction directed at a specific site in a DNA molecule. The most common method involves use of a chemically synthesised oligonucleotide mutant which can hybridise with the DNA target molecule. The resulting mismatch-carrying DNA duplex may then be transfected into a bacterial cell line and the mutant strands recovered. (12 Dec 1998) |
| site-directed mutagenesis | <molecular biology> Any of several methods used to create specific alterations in a gene. (09 Oct 1997) |
| site-specific mutagenesis | <cell culture, molecular biology> An in vitro technique in which an alteration is made at a specific site in a DNA molecule, which is then reintroduced into a cell. Various techniques are used, for the cell biologist, a very powerful approach to determining which parts of a protein or nucleotide sequence are critical to function. (18 Nov 1997) |
| transposon mutagenesis | <molecular biology> Insertion of a transposon into a gene, this inactivates the host gene leading to a mutant phenotype and also confers the phenotype associated with the transposon gene. (09 Oct 1997) |
| insertional mutagenesis |
The production of a mutation by insertion of 1 or more copies of a transgene into a host genome.
출처: www.kumc.edu/gec/gloss.html
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| insertional mutagenesis |
The generation of an insertion mutation by inserting one or more extra nucleotide bases into the DNA sequence.
출처: dragon.zoo.utoronto.ca/~B03T0801B/glossary.html
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| insertional mutagenesis |
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene. This process may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. [MeSH]
출처: www.bioon.com/book/biology/genomicglossaries/funct...
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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