| 영문 | codon | 한글 | 코돈, 유전자부호 |
|---|---|---|---|
| 설명 | 단백질의 아미노산 배열을 규정하는 전령 RNA의 3염기 배열을 말한다. 아미노산의 유전암호라고도 한다. 전 생물을 통해서 공통으로 DNA의 염기배열로 표시할 수도 있다. RNA또는 DNA를 구성하는 네 종류의 염기(뉴클레오티드)에서 만들어지는 염기배열의 총수는 64개로, 그 중의 61개가 아미노산을 코드하고 있다. 나머지 세 개(UAA, UAG, UGA)는 단백질 합성을 정지시킬 부호로 정지코돈이라 불린다. 단백질합성의 개시코돈(AUG)은 메티오닌의 코돈과 공통이지만 개시 tRNA에 의해서 인식된다. |
||
| EIF | erythrocyte initiation factor; eukaryotic initiation factor |
|---|---|
| eIF | erythrocyte initiation factor |
| IF | idiopathic fibroplasia; idiopathic flushing; immersion foot; immunofluorescence; indirect fluorescen... |
| CAI | Codon Adaptation Index |
|---|---|
| PTC | premature termination codon |
| eIF | Eukaryotic initiation factor |
| eIF-2 | Eukaryotic initiation factor 2 |
| eIF-2B | Eukaryotic initiation factor 2B |
| initiation codon | The codon 5' AUG in mRNA, at which polypeptide synthesis is started. It is recognised by formylmethionyl tRNA in bacteria and by methionyl tRNA in eukaryotes. (18 Nov 1997) |
|---|
| peptide chain initiation | The process whereby the formation of a peptide chain is started. This process requires (1) the 30s subunit, (2) the mRNA coding for the polypeptide to be made, (3) met-trnai, (4) initiation factors, and (5) GTP. (12 Dec 1998) |
|---|---|
| peptide initiation factors | Protein factors uniquely required during the initiation phase of protein synthesis. (12 Dec 1998) |
| initiation | 1. The first stage of tumour induction by a carcinogen; subtle alteration of cells by exposure to a carcinogenic agent so that they are likely to form a tumour upon subsequent exposure to a promoting agent (promotion). 2. Starting point of replication or translation in macromolecule biosynthesis. 3. Start of chemical or enzymatic reaction. (05 Mar 2000) |
| initiation complex | Complex between mRNA, 30S ribosomal subunit and formyl methionyl tRNA that requires GTP and initiation factors to function. (18 Nov 1997) |
| initiation factor | One of several soluble proteins involved in the initiation of protein or RNA synthesis. (05 Mar 2000) |
| initiation factors | The set of catalytic proteins required, in addition to mRNA and ribosomes, for protein synthesis to begin. In bacteria three distinct proteins have been identified: if 1 (8 kD), IF 2 (75 kD) and IF 3 (30 kD). at least 6-8 proteins have been identified in eukaryotes. IFs 1 and 2 enhance the binding of initiator tRNA to the initiation complex. (18 Nov 1997) |
| initiation tRNA | TRNA in prokaryotes containing a formyl-methionyl residue that initiates translation. Synonym: formyl-methionyl-tRNA, starter tRNA. (05 Mar 2000) |
| tumour initiation | <cell biology, oncology> First stage of tumour development. See: tumour progression. (18 Nov 1997) |
| amber codon | <molecular biology> One of the three terminator codons. Its sequence is UAG. See: ochre codon, opal codon. (18 Nov 1997) |
| ambiguous codon | <molecular biology> A codon that codes for more than one amino acid. (09 Oct 1997) |
| codon | <molecular biology> The coding unit of DNA that specifies the function of the corresponding messenger RNA. A triplet of bases recognised by anticodons on transfer RNA and hence specifying an amino acid to be incorporated into a protein sequence. The code is degenerate, i.e. Each amino acid has more than one codon. The stop codon determines the end of a polypeptide. (18 Nov 1997) |
| codon, initiator | Any codon that directs initiation of genetic translation (translation, genetic) by stimulating the binding of initiator trna. In prokaryotes, the codons aug or gug can act as initiators while in eukaryotes, aug is the only initiator codon. (12 Dec 1998) |
| codon, nonsense | A codon that is not assigned to an amino acid or to any stop signal. It was originally thought that nonsense codons were synonymous with terminator codons (codon, terminator) in that they signaled termination of a protein chain. Recent studies have found this not to be true. (12 Dec 1998) |
| codon, terminator | Any codon that signals the termination of genetic translation (translation, genetic) by triggering the hydrolysis of the aminoacyl bond connecting the completed polypeptide to the trna. Terminator codons (uaa, uag, and uga) do not specify amino acids. (12 Dec 1998) |
| punctuation codon | <molecular biology> The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis. They are not represented by any tRNA and termination is catalysed by protein release factors. There are two release factors in E. Coli, RF1 recognises UAA and UAG, RF2 recognises UAA and UGA. Eukaryotes have a single GTP requiring factor, eRF. See: ochre suppressor, amber suppressor. (13 Jan 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|