| ¿µ¹® | vaccine | ÇÑ±Û | ¹é½Å |
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| ¼³¸í | Àü¿°º´¿¡ ´ëÇÏ¿© ÀΰøÀûÀ¸·Î ¸é¿ªÀ» ÁÖ±â À§ÇØ »ýü¿¡ Åõ¿©ÇÏ´Â Ç׿øÀÇ Çϳª. º´¿øÃ¼ ¹× µ¶¼Ò¿¡ ´ëÇÑ ¹æ¾î±â±¸¸¦ °ÈÇÒ ¸ñÀûÀ¸·Î »ç¿ëµÇ´Â ¹Ì»ý¹°Á¦Á¦¸¦ ¸»ÇÑ´Ù. ÇÁ¶û½ºÀÇ ¹Ì»ý¹°ÇÐÀÚ L. ÆÄ½ºÅ𸣿¡ ÀÇÇÏ¿© Á¦Ã¢µÈ ¿ë¾î·Î¼, ¾î¶² °¨¿°Áõ¿¡ ´ëÇÏ¿© ÀΰøÀûÀ¸·Î ¸é¿ªÀ» ¾ò±â À§ÇÏ¿© ±× º´¿ø ¹Ì»ý¹° ¶Ç´Â ±× µ¶¼Ò¾×¿¡ Àû´çÇÑ Á¶ÀÛÀ» °¡ÇÏ¿© ¸¸µç °ÍÀ» ¸»ÇÑ´Ù. |
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| ¿µ¹® | influenza | ÇÑ±Û | ÀÎÇ÷翣ÀÚ |
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| ¼³¸í | ±âµµ¸¦ ħ¹üÇÏ´Â ¹ÙÀÌ·¯½º °¨¿°Áõ. Áö¿ªÀ¯Ç༺, À¯Ç༺ ¶Ç´Â ¹ü¹ß¼ºÀ¸·Î ¹ß»ýÇÑ´Ù. ¹ü¹ß¼ºÀÇ °æ¿ì´Â ¿©·¯ ´ë·úÀ» µ¿½Ã¿¡ ¶Ç´Â ¿¬¼ÓÀûÀ¸·Î ħ¹üÇÑ´Ù. ÄÚÁ¡¸·, ÀεÎ, °á¸·ÀÇ ¿°Áõ, µÎÅë, ¶§¶§·Î Àü½ÅÀÇ ½ÉÇÑ ±ÙÀ°ÅëÀÌ Æ¯Â¡ÀÌ´Ù. ½ÉÀå±Ù°ú ÁßÃ߽Űæ°è°¡ Ä§ÇØµÇ´Â ÀÏÀº Àû´Ù. ±«»ç±â°üÁö¿°°ú °£ÁúÆó·ÅÀÌ ÁßÁõ ÀÎÇ÷翣ÀÚÀÇ ÁÖµÈ Áõ»óÀÌ´Ù. ȯÀÚ´Â Æó·Å¾Ë±Õ(Streptococcus pneumoniae), ÀÎÇ÷翣ÀÚ±Õ(Hemophilus influenzae), Ȳ»öÆ÷µµ¾Ë±Õ(Staphylococus aureus)¿¡ ÀÇÇÑ ¼Ó¹ß¼º ¼¼±Õ¼º Æó·Å¿¡ °É¸®±â ½±´Ù. Àẹ±â´Â 1~3, Áúº´±â°£Àº Åë»ó 3~10ÀÏÀÌ´Ù. ÀÎÇ÷翣ÀÚ´Â A(¸¹Àº ¾Æ±ºÀÌ ÀÖ´Ù), B, C·Î À̸§Áö¾îÁø ¿©·¯ °¡ÁöÀÇ Ç÷ûÇÐÀûÀ¸·Î ´Ù¸¥ ¹ÙÀÌ·¯½ºÁÖ¿¡ ÀÇÇØ ¹ß»ýÇÑ´Ù. |
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| ¿µ¹® | influenza virus | ÇÑ±Û | ÀÎÇ÷翣ÀÚ¹ÙÀÌ·¯½º |
|---|---|---|---|
| ¼³¸í | ÀÎÇ÷翣ÀÚÀÇ º´¿øÃ¼. »ó±âµµ Á¡¸·¿¡ ħÀÔÇÏ¿© È£Èí±â ÁúȯÀ» ÀÏÀ¸Å²´Ù. º¸Ã¼ °áÇÕ Ç׿øÀÇ Â÷ÀÌ¿¡ µû¶ó A-B-C ¼¼ÇüÅ·Π³ª´µ¸ç, À¯ÇàÇÒ ¶§¸¶´Ù Ç÷±¸ ÀÀÁý Ç׿øÀÌ º¯ÀÌÇÏ¿© ±¤¹üÀ§ÇÑ À¯ÇàÀ» ³ªÅ¸³½´Ù. ²®ÁúÀÌ ÀÖ´Â 80~150nmÀÇ °ø¸ð¾ç, ³ª¼± ´ëĪ RNA ¹ÙÀÌ·¯½ºÀÌ´Ù. µÎ Á¾·ùÀÇ ½ºÆÄÀÌÅ©, ´º¶ó¹Ì´Ï´Ù¾ÆÁ¦(neuraminidase, NA), ´ç´Ü¹éÁú°ú Ç츶±Û·çƼ´Ñ(hemagglution, HA) ´ç´Ü¹éÁúÀ» ¸¸µç´Ù. AÇüÀÇ NA¿¡´Â N1-N2ÀÇ µÎ Á¾·ù, HA¿¡´Â HAO-HA1-HA2-HA3ÀÇ ³× Á¾·ù°¡ ÀÖ´Ù. AÇüÀº ¸»-µÅÁö-»õ¿¡ °¨¿°ÇÏ¸ç »õ·Î¿î ¾ÆÇüÀº µ¿¹° ¹ÙÀÌ·¯½º¿ÍÀÇ Á¶È¯ÇüÀ̸ç, ±× ¹Û¿¡ µ¿ÀÏ ¾ÆÇü³» Á¡º¯À̰¡ ÀÖ´Ù. B, CÇüÀº »ç¶÷ À̿ܿ¡´Â °¨¿°µÇÁö ¾Ê´Â´Ù. ´ßÀÇ ÀûÇ÷±¸¸¦ ÀÀÁýÇÏ´Â ¼ºÁúÀÌ ÀÖ´Ù. ¹ÙÀÌ·¯½º Áø´Ü¿¡´Â ȯÀÚÀÇ ÀεΠ¼¼Ã´¾×¿¡¼ ºÐ¸®ÇѴٵ簡, ¶Ç´Â ȯÀÚÀÇ Ç÷ûÇ×ü¿¡ ÀÇÇÑ Æ¯ÀÌÀû ÀûÇ÷±¸ ÀÀÁýÀúÁö°Ë»ç, ´º¶ó¹Ì´Ï´Ù¾ÆÁ¦ Ȱ¼ºÀúÁö°Ë»ç ¶Ç´Â ÁßÈ°Ë»ç µîÀ¸·Î °ËÃâÇÑ´Ù. |
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| HBPV | Haemophilus influenza type B Polysaccharide(PRP) Vaccine; BÇü Çì¸ðÇʷ罺 ÀÎÇ÷翣ÀÚ ÇǸ· ´Ù´çÁú ¹é½Å... |
|---|---|
| IVV | influenza virus vaccine; intravenous vasopressin |
| BHK | baby hamster kidney [cells]; type-B Hong Kong [influenza virus] |
| flu | influenza |
| CDPS | calcium-dependent protease small subunit |
| AI | Avian influenza |
|---|---|
| AIV | Avian influenza virus |
| Hib | H influenza type B |
| IAV | Influenza A virus |
| ILI | Influenza-Like Illness |
| subunit vaccine | <pharmacology> A vaccine composed of a purified antigenic determinant that is separated from the disease-causing organism. (06 Mar 1998) |
|---|---|
| vaccine, influenza | See Vaccine, flu. Vaccination, dtap: like dpt, dtap protects from diphtheria, pertussis (whooping cough) and tetanus. Dtap is the same as dtp, except that it contains only acellular pertussis vaccine which is thought to cause fewer of the minor reactions associated with immunization and is also probably less likely to cause the more severe reactions occasionally seen following pertussis vaccination. Dtap is currently recommended only for the shots given at 18 months and 4-6 years of age. Vaccination, dt: dt (diphtheria and tetanus) vaccine does not protect from pertussis and is usually reserved for individuals who have had a significant adverse reaction to a dpt shot or who have a personal or family history of a seizure disorder or brain disease. (12 Dec 1998) |
| Haemophilus influenza b vaccine | <virology> A vaccination that is given to infants to protect against infection with haemophilus influenza b, an important cause of neonatal sepsis. Typically administered at 2, 4, 6 and 15 months. Children who are aged 15 months to 5 years, who have not received the vaccine, should be given a single injection of haemophilus b conjugate vaccine. Acronym: HIB (26 Mar 1998) |
| influenza vaccine | A special vaccine which provides immunity to infection by a variety of Influenza viruses. The vaccine is updated annually due to the constant introduction of new viral strains. Flu vaccination programs are common in the elderly population and any other groups who are at increased risk of viral infection. (27 Sep 1997) |
| gamma subunit, cGMP phosphodiesterase | <enzyme> Isolated from canine retinal rod photoreceptor cells; genbank u49359 Registry number: EC 3.1.14.- Synonym: pde-gamma, pdegamma, cgmp-pde gamma subunit (26 Jun 1999) |
| glycoprotein hormones, alpha subunit | A non-covalently bound subunit of the glycoprotein hormones tsh, fsh, lh, and hcg which originates in the anterior pituitary gland and placenta. This subunit is virtually identical in structure and indistinguishable by radioimmunoassay in all of the above glycoproteins. It is present in both men and women, but is elevated in postmenopausal women and in patients with hypothyroidism, uraemia and malignant tumours. The alpha subunit may be involved directly in recognition of certain receptors. (12 Dec 1998) |
| ribulose-1,5-bisphosphate carboxylase-oxygenase large subunit epsilonN-methyltransferase | <enzyme> An aspect of EC 2.1.1.43; trimethylates lys-14 of rubisco Registry number: EC 2.1.1.- Synonym: rubisco lsmt, rubisco large subunit lysine n-methyltransferase (26 Jun 1999) |
| cholera toxin, B subunit-horseradish peroxidase | <chemical> Conjugate of horseradish peroxidase and cholera toxin Synonym: bhrp, horseradish peroxidase-cholera toxin b subunit, cholera toxin-horseradish peroxidase, horseradish peroxidase-cholera toxin, ib4-hrp (26 Jun 1999) |
| chorionic gonadotropin, beta subunit, human | The beta subunit of human chorionic gonadotropin. It is used as a clinical marker to facilitate early detection of normal pregnancy and significantly contributes to the diagnosis of various pregnancy-related disorders, such as ectopic pregnancy, spontaneous abortion, hydatidiform mole, choriocarcinoma, or trisomy 21. Further, determination of this marker is immensely helpful to guide curative intervention in testicular cancer. Other possible clinical uses includes as a marker of cancers of the bladder, pancreas, or biliary tract. (scan j clin lab invest suppl 1993;216:97-104) (12 Dec 1998) |
| phycocyanin alpha-subunit phycocyanobilin lyase | <enzyme> Cleaves thioether bond attaching phycocyanobilin to the alpha subunit of phycocyanin; product of the cpce and cpcf genes of synechococcus Registry number: EC 4.4.- Synonym: phycocyanobilin lyase (26 Jun 1999) |
| phycoerythrocyanin alpha-subunit phycobiliviolin lyase | <enzyme> Shows high degree of homology to phycocyanobilin lyase Registry number: EC 4.4.- Synonym: phycobiliviolin lyase, pece protein, pecf protein, pec alpha-subunit phycobiliviolin lyase (26 Jun 1999) |
| signal peptide p25-subunit IV cytochrome oxidase | <chemical> Similar in action to melittin Synonym: p25 presequence peptide-cytochrome oxidase, pre-ctox p25 (26 Jun 1999) |
| subunit | <cell biology> Components from which a structure is built, thus myosin has six subunits, microtubules are built of tubulin subunits. In some cases it may be more informative to speak of protomers. (06 Mar 1998) |
| Asian influenza | A worldwide influenza, apparently originating in China in the summer of 1957, which produces a milder disease than that of the pandemic of 1917-1919. (05 Mar 2000) |
| avian influenza | Infection of domestic and wild fowl and other birds with influenza a virus, avian. (12 Dec 1998) |
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