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| ¿µ¹® | scratch test | ÇÑ±Û | ³Àý¹ý |
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| ICT | icteric, icterus; indirect Coombs test; inflammation of connective tissue; insulin coma therapy; int... |
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| AGT | Anti-Globulin Test = Coombs' Test |
| CT | calcitonin; calf testis; cardiac tamponade; cardiothoracic [ratio]; carotid tracing; carpal tunnel; ... |
| DCT | direct Coombs' test; discrete cosine transform; distal convoluted tubule; diurnal cortisol test; dyn... |
| IFA | idiopathic fibrosing alveolitis; immunofluorescence assay; immunofluorescent antibody; incomplete Fr... |
| IFAT | Indirect Fluorescence Antibody Test |
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| IFA | Indirect Fluorescent Antibody Test |
| IFAT | Indirect Fluorescent Antibody Test |
| IHA | Indirect Haemagglutination Test |
| IHAT | Indirect Haemagglutination Test |
| indirect Coombs' test | A test routinely performed in cross-matching blood or in the investigation of transfusion reaction: test for patient's serum is incubated with a suspension of donor erythrocytes; if specific antibodies are present, they become attached to the antigen in donor's cells; after a washing with saline, Coombs' antihuman globulin is added; agglutination at this point indicates that antibodies present in the original test serum had indeed become attached to donor erythrocytes. (05 Mar 2000) |
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| coombs' test | Haemagglutination test in which coombs' reagent (antiglobulin, or anti-human globulin rabbit immune serum) is added to detect incomplete (non-agglutinating, univalent, blocking) antibodies coating erythrocytes. The direct test is applied to red cells which have been coated with antibody in vivo (e.g., in haemolytic disease of newborn, autoimmune haemolytic anaemia, and transfusion reactions). The indirect test is applied to serum to detect the presence of antibody (e.g., in detection of incompatibility in cross-matching tests, detection and identification of irregular antibodies, and in detection of antibodies not identifiable by other means). (12 Dec 1998) |
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| direct Coombs' test | A test for detecting sensitised erythrocytes in erythroblastosis foetalis and in cases of acquired immune haemolytic anaemia: the patient's erythrocytes are washed with saline to remove serum and unattached antibody protein, then incubated with Coombs' anti-human globulin (usually serum from a rabbit or goat previously immunised with human globulin); after incubation, the system is centrifuged and examined for agglutination, which indicates the presence of so-called incomplete or univalent antibodies on the surface of the erythrocytes. (05 Mar 2000) |
| indirect haemagglutination test | A kind of passive agglutination in which erythrocytes, usually modified by mild treatment with tannic acid or other chemicals, are used to adsorb soluble antigen onto their surface, and which then agglutinate in the presence of antiserum specific for the adsorbed antigen. Synonym: indirect haemagglutination test. (05 Mar 2000) |
| Carey Coombs murmur | A blubbering apical middiastolic murmur occurring in the acute stage of rheumatic mitral valvulitis and disappearing as the valvulitis subsides. Synonym: Coombs murmur. (05 Mar 2000) |
| Gell and Coombs Classification | A classification system that differentiates the 4 types of hypersensitivity reactions: Type I: anaphylactic reactions, Type II: cytotoxic reactions, Type III: immune complex reactions, and Type IV: cell-mediated reactions. (05 Mar 2000) |
| Coombs, Carey | <person> English physician, 1879-1932. See: Coombs murmur. (05 Mar 2000) |
| Coombs murmur | A blubbering apical middiastolic murmur occurring in the acute stage of rheumatic mitral valvulitis and disappearing as the valvulitis subsides. Synonym: Coombs murmur. (05 Mar 2000) |
| coombs' reaction | An immunological lab test to detect antibodies which attack the red blood cells of its own body (called autoantibodies). The test is important to the diagnosis of certain blood disorders. The test first reacts red blood cells with serum from the test individual, then with antibodies to the autoantibodies. If the autoantibodies exist, they will bind to the red blood cells. When the antibodies to the autoantibodies are added, they will bind the autoantibodies (still attached to the red blood cells) and cause the red blood cells to clump together. Large clumps of red blood cells indicate that the autoantibodies exist, absence of the clumps indicates that they don't. (09 Oct 1997) |
| Coombs, Robin | <person> English veterinarian and immunologist, *1921. See: Gell and Coombs reactions, Coombs' serum, Coombs' test, direct Coombs' test, indirect Coombs' test. (05 Mar 2000) |
| Coombs' serum | Serum from a rabbit or other animal previously immunised with purified human globulin to prepare antibodies directed against IgG and complement; used in the direct and indirect Coombs' tests. Synonym: Coombs' serum. (05 Mar 2000) |
| calorimetry, indirect | Calculation of the energy expenditure in the form of heat production of the whole body or individual organs based on respiratory gas exchange. (12 Dec 1998) |
| indirect | 1. Not immediate or straight. 2. Acting through an intermediary agent. Origin: L. Indirectus (18 Nov 1997) |
| indirect agglutination | Agglutination of particles that have been coated with soluble antigen, by antiserum specific for the adsorbed antigen. Synonym: indirect agglutination. (05 Mar 2000) |
| indirect assay | For antibody; an application of the ELISA method in which serum being tested for antibody is added to wells coated with known antigen; presence of antibody bound to the antigen coat can be determined by addition of immunoglobulin-specific antibody to which is linked the enzyme of the indicator system, followed by addition of substrate to the washed aggregate. (05 Mar 2000) |
| indirect bilirubin | <biochemistry> Free bilirubin that has not been attached to a glucuronide molecule. This results from the rapid breakdown of red blood cells. The haemoglobin molecule is normally converted to bilirubin. Greater than normal values of indirect bilirubin can be seen in erythroblastosis foetalis, haemolytic anaemia, sickle cell anaemia, transfusion reactions, pernicious anaemia and resolution of large haematomas. (27 Sep 1997) |
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