| APP | acute phase protein; alum-precipitated pyridine; aminopyrazolopyrimidine; amyloid peptide precursor;... |
|---|---|
| ECP | ectrodactyly-cleft palate [syndrome]; effector cell precursor; endocardial potential; eosinophil cat... |
| Xi | inactive X Chromosome |
| CAC/CIC | chronic active/inactive cirrhosis |
| IRA | immunoradioassay; immunoregulatory alpha-globulin; inactive renin activity |
| IR | inactive renin |
|---|---|
| APUD | Amine Precursor Uptake and Decarboxylation |
| APP | Amyloid Precursor Protein |
| APLP | amyloid precursor-like protein |
| APP | Amyloid Protein Precursor |
| inactive | Not active. (18 Nov 1997) |
|---|---|
| inactive mutant | A mutant that is not phenotypically manifest. Synonym: silent mutant. (05 Mar 2000) |
| inactive repressor | A repressor that cannot combine with an operator gene until it has combined with a corepressor (usually a product of a protein pathway); after activation, the repressor arrests production of the proteins controlled by the operator gene; a homeostatic mechanism for regulation of repressible enzyme systems. Synonym: aporepressor. (05 Mar 2000) |
| inactive tuberculosis | A scar or a calcified, fibrous, or caseous nodule in the lung pleura, lymph node, or other organ, resulting from previous tuberculosis that has regressed; reactivation is possible. Synonym: arrested tuberculosis, inactive tuberculosis. (05 Mar 2000) |
| Amine Precursor Uptake and Decarboxylation | <pharmacology, physiology> Paracrine cells of which argentaffin cells are an example. Usage of the term APUD is neither helpful nor memorable. Acronym: APUD (11 Nov 1997) |
| amyloid beta-protein precursor | A precursor to the amyloid-beta protein (beta/a4). Alterations in the expression of the amyloid beta-protein precursor (abpp) gene, located on chromosome 21, plays a role in the development of the neuropathology common to both alzheimer disease and down syndrome. Abpp is associated with the extensive extracellular matrix secreted by neuronal cells. Upon cleavage, this precursor produces three proteins of varying amino acid lengths: 695, 751, and 770. The beta/a4 (695 amino acids) or beta-amyloid protein is the principal component of the extracellular amyloid in senile plaques found in alzheimer disease, down syndrome and, to a limited extent, in normal aging. (12 Dec 1998) |
| amyloid precursor protein | <protein> Individuals with Alzheimer's disease are characterised by extensive accumulation of amyloid in the brain, referred to as senile plaques. These consist of a core of amyloid fibrils surrounded by dystrophic neurites. The principal component of the amyloid fibrils is B/A4, a peptide derived from the larger APP. The specific role of amyloid protein is unclear but it is thought that amyloid deposits may cause neurons to degenerate. Amyloid deposits also occur in brains of older Down's Syndrome patients. (04 May 1997) |
| angiotensin precursor | angiotensin |
| precursor | Something that precedes. 1. <biochemistry> In biological processes, a substance from which another, usually more active or mature substance is formed. 2. In clinical medicine, a sign or symptom that heralds another. Origin: L. Praecursor = a forerunner (18 Nov 1997) |
| enzyme precursor | <biochemistry> Inactive precursors that can be converted to active enzymes. Enzyme precursors containing extra-long polypeptide chains that block activity are activated by acid or enzymatic hydrolysis to remove the inhibiting portion. (12 Dec 1998) |
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