| IDI | immunologically detectable insulin; induction-delivery interval; inter-dentale inferius |
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| IMD | immunodeficiency; immunologically mediated disease; institution for mentally disabled |
| IMI | immunologically measurable insulin; impending myocardial infarction; Imperial Mycological Institute ... |
| SICRI | substance immunologically cross reactive with insulin |
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| AEBS | Antiestrogen binding sites |
| DHS | DNAse I hypersensitive sites |
| EBS | ETS binding sites |
| FS | Fragile Sites |
| immunologically privileged sites | Sites where allografts are not readily rejected, probably because these particular areas have poor lymphatic drainage. (05 Mar 2000) |
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| privileged | Invested with a privilege; enjoying a peculiar right, advantage, or immunity. Privileged communication. Witnesses who are not obliged to testify as to certain things, as lawyers in relation to their dealings with their clients, and officers of state as to state secrets; also, by statute, clergymen and physicans are placed in the same category, so far as concerns information received by them professionally. Source: Websters Dictionary (01 Mar 1998) |
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| privileged site | An anatomic area lacking lymphatic drainage, such as the brain, cornea, and hamster cheek pouch, in which heterologous tumours may grow because the host does not become sensitised. (05 Mar 2000) |
| immunologically activated cell | An immunocyte that is in an elevated state of reactivity capable of carrying out an immune response, in contradistinction to an immunologically competent cell. (05 Mar 2000) |
| immunologically competent cell | A small lymphocyte capable of being immunologically activated by exposure to a substance that is antigenic (immunogenic) for the respective cell; activation involves either the capacity to produce antibody or the capacity to participate in cell-mediated immunity. (05 Mar 2000) |
| attachment sites | <microbiology, molecular biology> Particular loci in both bacterial and phage DNA molecules at which phage DNA is integrated into the bacterial DNA by recombination between these sites. (12 Dec 1998) |
| binding sites | The reactive parts of a macromolecule that directly participate in its specific combination with another molecule. (12 Dec 1998) |
| binding sites, antibody | Local surface sites on antibodies which react with antigen determinant sites on antigens. They are formed from parts of the variable regions of the fab fragment of the immunoglobulin. (12 Dec 1998) |
| chromosome fragile sites | Heritable sensitive regions of chromosomes which show up in vitro as non-staining bands. They are associated with chromosome breakage and other aberrations, and, when located on sex chromosomes, they produce phenotypic abnormalities. No abnormal phenotype has been definitely identified with autosomal fragile sites, but some rare autosomal recessive disorders may be due to homozygosity for fragile sites. Fragile sites are designated by the letters "fra" followed by the designation for the specific chromosome and locus. (12 Dec 1998) |
| contact sites A | Developmentally regulated adhesion sites that appear on the ends of aggregation competent Dictyostelium discoideum at the stage when the starved cells begin to come together to form the grex. Originally detected by the use of Fab fragments of polyclonal antibodies, raised against aggregation competent cells and adsorbed against vegetative cells, to block adhesion in EDTA containing medium. (Cell cell adhesion mediated by contact sites A, unlike that mediated by contact sites B, is not divalent cation sensitive). The fact that a mutant deficient in csA behaves perfectly normally in culture is puzzling. (18 Nov 1997) |
| contact sites B | Developmentally regulated adhesion sites that appear on the ends of aggregation competent Dictyostelium discoideum at the stage when the starved cells begin to come together to form the grex. Originally detected by the use of Fab fragments of polyclonal antibodies, raised against aggregation competent cells and adsorbed against vegetative cells, to block adhesion in EDTA containing medium. (Cell cell adhesion mediated by contact sites A, unlike that mediated by contact sites B, is not divalent cation sensitive). The fact that a mutant deficient in csA behaves perfectly normally in culture is puzzling. (18 Nov 1997) |
| crohn disease: sites | <radiology> Oesophagus: rare, stomach (2-20%): granulomatous gastritis, pseudo-post Bilroth-I appearance, ramshorn sign, antral-duodenal fistula, duodenum (4-10%): almost always associated with gastric involvement, bulb and proximal half of duodenum, small bowel (80%): regional enteritis, terminal ileum (alone/in combination): 95%, jejunum/ileum: 15%, commonly associated with medial caecal defect, colon (22-55%): granulomatous colitis, particularly on the right side, transverse stripe sign: contrast within coarse mucosal folds, rectum (35-50%) see: Crohn disease (12 Dec 1998) |
| sequence tagged sites | Short, tagged tracts of DNA sequence that are used as landmarks in genome mapping. In most instances, 200 to 500 base pairs of sequence define a sequence tagged site (sts) that is operationally unique in the human genome (i.e., can be specifically detected by the polymerase chain reaction in the presence of all other genomic sequences). The overwhelming advantage of stss over mapping landmarks defined in other ways is that the means of testing for the presence of a particular sts can be completely described as information in a database. (12 Dec 1998) |
| sequence-tagged sites | Short stretches of DNA sequences that can be detected by use of the polymerase chain reaction. (05 Mar 2000) |
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