| ¿µ¹® | inguinal region of abdomen | ÇÑ±Û | »ô, ¼ÇýºÎ, »ô°í¶û |
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| MIg | malaria immunoglobulin; measles immunoglobulin; membrane immunoglobulin |
|---|---|
| PAR | participating provider; passive avoidance reaction; perennial allergic rhinitis; photosynthetically ... |
| dpdt | double-pole double-throw [switch] |
| dpst | double-pole single-throw [switch] |
| SCS | Saethre-Chotzen syndrome; shared computer system; silicon-controlled switch; Society of Clinical Sur... |
| ASO | Arterial switch operation |
|---|---|
| CSR | class switch recombination |
| S | switch |
| Ig | Anti-immunoglobulin |
| anti-Ig | Anti-immunoglobulin |
stress-bearing region
| immunoglobulin switch region | Site on a segment of a B-cell immunoglobulin heavy-chain gene where recombination or rearrangement can occur, expressed as isotype or allotype switching, maturation of immune response, or recombination of DNA molecules. It is found on genes encoding all five immunoglobulin heavy chains. (12 Dec 1998) |
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| switch region | <molecular biology> The nucleotide sequences in heavy chain immunoglobulin genes located in the introns at the 5' end of each CH locus concerned with DNA recombination events that lead to changes in the type of heavy chain produced by a B-cell, for example IgM to IgG switching. These regions are highly conserved sequences. See: isotype switching. (19 Jan 1998) |
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| immunoglobulin constant region | That region of the immunoglobulin (antibody) molecule that is invariable in its amino acid sequence within any class of immunoglobulins. It confers the biological specificity to the ig and is grossly species specific. It comprises the c-terminus half of the light chains and three quarters or more of the heavy chains, all of the fc fragment, and the c-terminus half of the fab fragment. (12 Dec 1998) |
| immunoglobulin joining region | Segment of light and heavy chains of mouse and human immunoglobulins where the genes for the variable region upstream join those of the constant region downstream (an important part of the antibody diversity mechanism). In the joining region of the light chain are the genes coding for amino acids 96 to 107. (12 Dec 1998) |
| immunoglobulin variable region | That region of the immunoglobulin (antibody) molecule that varies in its amino acid sequence and composition, confers the antigenic specificity, and is thought to comprise the binding site for the antigen. It is located at the n-terminus of the fab fragment of the immunoglobulin. It includes hypervariable and framework regions, vh family subgroups, and the complementarity-determining region. (12 Dec 1998) |
| arterial switch operation | Operation for complete transposition of the great arteries; the most common way to repair this defect consists of switching the aorta and pulmonary arteries and implanting the coronary arteries into the neoaorta (the original pulmonary artery). (05 Mar 2000) |
| genes, switch | Genes that cause the epigenotype (i.e., the interrelated developmental pathways through which the adult organism is realised) to switch to an alternate cell lineage-related pathway. Switch complexes control the expression of normal functional development as well as oncogenic transformation. (12 Dec 1998) |
| gene switch | <molecular biology> A situation in which a cell or organism stops expressing one gene orgene group and switches to expressing a different gene or group of genes. (09 Oct 1997) |
| class switch | Change in the isotype of antibody produced after a B-cell has encountered an antigen. (05 Mar 2000) |
| switch | 1. To strike with a switch or small flexible rod; to whip. 2. To swing or whisk; as, to switch a cane. 3. To trim, as, a hedge. 4. To turn from one railway track to another; to transfer by a switch; generally with off, from, etc.; as, to switch off a train; to switch a car from one track to another. 5. To shift to another circuit. Origin: Switched; Switching. 1. A small, flexible twig or rod. "Mauritania, on the fifth medal, leads a horse with something like a thread; in her other hand she holds a switch." (Addison) 2. A movable part of a rail; or of opposite rails, for transferring cars from one track to another. 3. A separate mass or trees of hair, or of some substance (at jute) made to resemble hair, worn on the head by women. 4. A mechanical device for shifting an electric current to another circuit. Safety switch, an arrangement of tracks whereby elevations otherwise insurmountable are passed. The track ascends by a series of zigzags, the engine running alternately forward and back, until the summit is reached. <physics> Switch board, a collection of switches in one piece of apparatus, so arranged that a number of circuits may be connected or combined in any desired manner. Switch grass. <botany> See Grass. Origin: Cf. OD. Swick a scourage, a whip. Cf. Swink, Swing. Source: Websters Dictionary (01 Mar 1998) |
| q-switch | <radiobiology> Optical switch used to rapidly change the Q of an optical resonator, utilised in the optical resonator of a laser to prevent lasing action until a high level of gain and energy storage are achieved in the laser medium. When the switch is triggered and rapidly increases the Q of the cavity, a stronger laser pulse is generated. See: oscillator. (09 Oct 1997) |
| anti-D immunoglobulin | rHo(D) immune globulin |
| rabies immunoglobulin | rabies immune globulin (human) |
| genes, immunoglobulin | Genes encoding the light and heavy chain segments of immunoglobulins. Light chain gene segments are symbolised l-v (variable), j (joining) and c (constant); ig heavy chain segments have, in addition, a diversity (d) gene. Each segment codes for certain amino acids, and each has a different nucleotide sequence; the genes are assembled by a remarkable shuffling of the segments during b lymphocyte maturation. (12 Dec 1998) |
| receptors, polymeric immunoglobulin | Specialised fc receptors (receptors, fc) for polymeric immunoglobulins, which mediate transcytosis of polymeric IgA and IgM into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IgA, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (secretory component) that is bound to IgA is proteolytically cleaved from its transmembrane tail. (12 Dec 1998) |
| measles immunoglobulin | measles immune globulin (human) |
Synonyms : Heavy-Chain Mu Switch Region, Ig Switch Sequences, Ig Switch Sequence, Immunoglobulin Switch Regions, Region, Immunoglobulin Switch, Regions, Immunoglobulin Switch, Sequence, Ig Switch, Sequences, Ig Switch, Switch Regions, Immunoglobulin, Switch Sequence, Ig
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