| ¿µ¹® | inguinal region of abdomen | ÇÑ±Û | »ô, ¼ÇýºÎ, »ô°í¶û |
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| MIg | malaria immunoglobulin; measles immunoglobulin; membrane immunoglobulin |
|---|---|
| JP | Jackson-Pratt [drain]; joining peptide; juvenile periodontitis |
| PAR | participating provider; passive avoidance reaction; perennial allergic rhinitis; photosynthetically ... |
| IGHV | immunoglobulin heavy chain variable region |
| bcr | breakpoint cluster region |
| J | D)-joining |
|---|---|
| JH | Joining |
| JP | Joining Peptide |
| NJ | Neighbor-Joining |
| NHEJ | Non-homologous DNA end joining |
stress-bearing region
| immunoglobulin joining region | Segment of light and heavy chains of mouse and human immunoglobulins where the genes for the variable region upstream join those of the constant region downstream (an important part of the antibody diversity mechanism). In the joining region of the light chain are the genes coding for amino acids 96 to 107. (12 Dec 1998) |
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| joining segment | <molecular biology> A small DNA segment that links genes to yield a functional gene encoding an immunoglobulin. (09 Oct 1997) |
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| immunoglobulin constant region | That region of the immunoglobulin (antibody) molecule that is invariable in its amino acid sequence within any class of immunoglobulins. It confers the biological specificity to the ig and is grossly species specific. It comprises the c-terminus half of the light chains and three quarters or more of the heavy chains, all of the fc fragment, and the c-terminus half of the fab fragment. (12 Dec 1998) |
| immunoglobulin switch region | Site on a segment of a B-cell immunoglobulin heavy-chain gene where recombination or rearrangement can occur, expressed as isotype or allotype switching, maturation of immune response, or recombination of DNA molecules. It is found on genes encoding all five immunoglobulin heavy chains. (12 Dec 1998) |
| immunoglobulin variable region | That region of the immunoglobulin (antibody) molecule that varies in its amino acid sequence and composition, confers the antigenic specificity, and is thought to comprise the binding site for the antigen. It is located at the n-terminus of the fab fragment of the immunoglobulin. It includes hypervariable and framework regions, vh family subgroups, and the complementarity-determining region. (12 Dec 1998) |
| anti-D immunoglobulin | rHo(D) immune globulin |
| rabies immunoglobulin | rabies immune globulin (human) |
| genes, immunoglobulin | Genes encoding the light and heavy chain segments of immunoglobulins. Light chain gene segments are symbolised l-v (variable), j (joining) and c (constant); ig heavy chain segments have, in addition, a diversity (d) gene. Each segment codes for certain amino acids, and each has a different nucleotide sequence; the genes are assembled by a remarkable shuffling of the segments during b lymphocyte maturation. (12 Dec 1998) |
| receptors, polymeric immunoglobulin | Specialised fc receptors (receptors, fc) for polymeric immunoglobulins, which mediate transcytosis of polymeric IgA and IgM into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IgA, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (secretory component) that is bound to IgA is proteolytically cleaved from its transmembrane tail. (12 Dec 1998) |
| measles immunoglobulin | measles immune globulin (human) |
| cellular immunodeficiency with abnormal immunoglobulin synthesis | An ill-defined group of sporadic disorders of unknown cause, occurring in both males and females and associated with recurrent bacterial, fungal, protozoal, and viral infections; there is thymic hypoplasia with depressed cellular (T-lymphocyte) immunity combined with defective humoral (B-lymphocyte) immunity, although immunoglobulin levels may be normal. Synonym: Nezelof syndrome, Nezelof type of thymic alymphoplasia. (05 Mar 2000) |
| Rho(D) immunoglobulin | rHo(D) immune globulin |
| chickenpox immunoglobulin | chickenpox immune globulin (human) |
| pertussis immunoglobulin | A sterile solution of globulin's derived from the plasma of adult human donors who have been immunised with pertussis vaccine; used both prophylactically and therapeutically. Synonym: pertussis immunoglobulin. (05 Mar 2000) |
| monoclonal immunoglobulin | A homogenous immunoglobulin resulting from the proliferation of a single clone of plasma cells and which, during electrophoresis of serum, appears as a narrow band or "spike"; it is characterised by heavy chains of a single class and subclass, and light chains of a single type. Synonym: M protein, monoclonal protein, paraprotein. (05 Mar 2000) |
| poliomyelitis immunoglobulin | poliomyelitis immune globulin (human) |
Synonyms : Immunoglobulin Joining Region Peptide Fragments, Ig Joining Region, Joining Region, Immunoglobulin
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