| 영문 | immunoglobulin | 한글 | 면역글로불린 |
|---|---|---|---|
| 설명 | 혈청성분 중 면역에 중요한 역할을 하고, 또 항체 작용을 하는 단백질의 총칭. 항체 작용이란 항원에 선택적으로 반응하는 기능인데, 이 작용을 하는 것은 대부분 전기이동법으로 나눌 경우 감마 영역에 속하므로 감마글로불린이라고도 한다. 기본구조는 분자량 약 2만 3,000의 L사슬(가벼운 사슬) 한 쌍과 5만~7만의 H사슬(무거운 사슬) 한 쌍이 S-S 다리걸침에 의해 결합된 것이다.  |
||
| MIg | malaria immunoglobulin; measles immunoglobulin; membrane immunoglobulin |
|---|---|
| AH | 1) Atrial Hypertrophy 2) Anti-Hyaluronidase 3) Amyloid imm... |
| AL | Amyloid immunoglobulin Light chain protein |
| TBII | TSH Binding Inhibiting(= Inhibition) Immunoglobulin |
| TSI | 1) Thyroid Stimulating Immunoglobulin 2) Triple Sugar Iron agar |
| CBD | Cellulose-binding domains |
|---|---|
| DD | Death domains |
| RBD | RNA binding Domains |
| MSD | membrane spanning domains |
| Ig | Anti-immunoglobulin |
| immunoglobulin domains | Structural units of immunoglobulin heavy or light chains that are composed of approximately 110 amino acids. Light chains of an immunoglobulin are composed of one constant domain and one variable domain. Heavy chains are composed of either three or four constant domains and one variable domain. (05 Mar 2000) |
|---|
| VH and VL genes/domains | VH and VL genes define in part the sequences of the variable heavy and light regions of immunoglobulin molecules. VH and VL domains are the regions of amino acid sequence so defined. J genes and, in the case of the heavy chain, a D gene (D=diversity) also define these regions. Gene rearrangement also plays a role in determining the sequences in which the genes are joined as the DNA of the immunoglobulin producing cell matures. (18 Nov 1997) |
|---|---|
| SH domains | <molecular biology> Src homology domains: domains of protein that, from their homology with src are involved in the interaction with phosphorylated tyrosine residues on other proteins (SH2 domains) or with proline rich sections of other proteins (SH3 domains). (18 Nov 1997) |
| src homology domains | Regions of sequence similarity in the src family of cytoplasmic tyrosine kinases. The sh1 domain is a catalytic domain. Sh2 and sh3 domains are protein-binding domains. Sh2 usually binds phosphotyrosine-containing proteins and sh3 interacts with cytoskeletal proteins. (12 Dec 1998) |
| domains | 1. Homologous units of approximately 110 to 120 amino acids each which comprise the light and heavy chains of the immunoglobulin molecule and which serve specific functions. The light chain has two domains's, one in the variable region and one in the constant region of the chain; the heavy chain has four to five domains's, depending upon the class of immunoglobulin, one in the variable region and the remaining ones in the constant region. 2. A region of a protein having some distinctive physical feature or role. Origin: Fr. Domaine, fr. L. Dominium, property, dominion (05 Mar 2000) |
| anti-D immunoglobulin | rHo(D) immune globulin |
| rabies immunoglobulin | rabies immune globulin (human) |
| genes, immunoglobulin | Genes encoding the light and heavy chain segments of immunoglobulins. Light chain gene segments are symbolised l-v (variable), j (joining) and c (constant); ig heavy chain segments have, in addition, a diversity (d) gene. Each segment codes for certain amino acids, and each has a different nucleotide sequence; the genes are assembled by a remarkable shuffling of the segments during b lymphocyte maturation. (12 Dec 1998) |
| receptors, polymeric immunoglobulin | Specialised fc receptors (receptors, fc) for polymeric immunoglobulins, which mediate transcytosis of polymeric IgA and IgM into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IgA, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (secretory component) that is bound to IgA is proteolytically cleaved from its transmembrane tail. (12 Dec 1998) |
| measles immunoglobulin | measles immune globulin (human) |
| cellular immunodeficiency with abnormal immunoglobulin synthesis | An ill-defined group of sporadic disorders of unknown cause, occurring in both males and females and associated with recurrent bacterial, fungal, protozoal, and viral infections; there is thymic hypoplasia with depressed cellular (T-lymphocyte) immunity combined with defective humoral (B-lymphocyte) immunity, although immunoglobulin levels may be normal. Synonym: Nezelof syndrome, Nezelof type of thymic alymphoplasia. (05 Mar 2000) |
| Rho(D) immunoglobulin | rHo(D) immune globulin |
| chickenpox immunoglobulin | chickenpox immune globulin (human) |
| pertussis immunoglobulin | A sterile solution of globulin's derived from the plasma of adult human donors who have been immunised with pertussis vaccine; used both prophylactically and therapeutically. Synonym: pertussis immunoglobulin. (05 Mar 2000) |
| monoclonal immunoglobulin | A homogenous immunoglobulin resulting from the proliferation of a single clone of plasma cells and which, during electrophoresis of serum, appears as a narrow band or "spike"; it is characterised by heavy chains of a single class and subclass, and light chains of a single type. Synonym: M protein, monoclonal protein, paraprotein. (05 Mar 2000) |
| poliomyelitis immunoglobulin | poliomyelitis immune globulin (human) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|