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| ITP | idiopathic thrombocytopenic purpura; immune thrombocytopenia; immunogenic thrombocytopenic purpura; ... |
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| TAR | Thrombocytopenia-Absent Radius |
| DIT | deferoxamine infusion test; diet-induced thermogenesis; diiodotyrosine; drug-induced thrombocytopeni... |
| HAT | Halsted Aphasia Test; head, arm, trunk; heparin-associated thrombocytopenia; heterophil antibody tit... |
| HATT | heparin-associated thrombocytopenia and thrombosis |
| ITP | Immune thrombocytopenia |
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| AITP | Autoimmune thrombocytopenia |
| HAT | Heparin associated thrombocytopenia |
| HIT | Heparin induced thrombocytopenia |
| HIT II | Heparin-induced thrombocytopenia type II |
| immune thrombocytopenia | Thrombocytopenia associated with antiplatelet antibodies. See: isoimmune neonatal thrombocytopenia, autoimmune neonatal thrombocytopenia. (05 Mar 2000) |
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| autoimmune thrombocytopenia purpura | <haematology> A rare autoimmune disorder characterised by an acute shortage of platelets with resultant bruising and spontaneous bleeding. The platelet count becomes exceedingly low and spontaneous bleeding from the gums, gastrointestinal tract and nose can be seen. Physical examination may demonstrate enlargement of the spleen. A typical rash occurs to do microscopic haemorrhage of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous haemorrhage into the brain causing death. Treatment with corticosteroids is generally effective. Surgical removal of the spleen (splenectomy) is reserved for some patients. Anti-platelet antibodies are detectable in some cases. It may present in either an acute or a chronic form. Acronym: ITP (20 Sep 2002) |
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| canine infectious cyclic thrombocytopenia | An infection of dogs with the rickettsia Ehrlichia platys characterised by recurrent cyclic thrombocytopenia. (05 Mar 2000) |
| radial aplasia-thrombocytopenia syndrome | <syndrome> Aplasia (absence) of the radius (the long bone on the thumb-side of the forearm) and thrombocytopenia (low blood platelets) are key features characterizing this syndrome. There is phocomelia (flipper-limb) with the thumbs always present. The fibula (the smaller bone in the lower leg) is often absent. The risk of bleeding from too few platelets is high in early infancy but lessens with age. The condition is inherited in an autosomal recessive trait with one gene (on a non-sex chromosome) coming from each parent to the child affected with the disease. Alternative names include thrombocytopenia-absent radius syndrome, tar syndrome, and tetraphocomelia-thrombocytopenia syndrome. (12 Dec 1998) |
| haemangioma-thrombocytopenia syndrome | <syndrome> Thrombocytopenia caused by sequestration and destruction of platelets in a large cavernous haemangioma, usually seen in infants, rare in adults (12 Dec 1998) |
| syndrome, radial aplasia-thrombocytopenia | See syndrome, tar. (12 Dec 1998) |
| syndrome, tetraphocomelia-thrombocytopenia | See syndrome, tar. (12 Dec 1998) |
| syndrome, thrombocytopenia-absent radius | See Syndrome, TAR. (12 Dec 1998) |
| idiopathic thrombocytopenia purpura | <haematology> A rare autoimmune disorder characterised by an acute shortage of platelets with resultant bruising and spontaneous bleeding. The platelet count becomes exceedingly low and spontaneous bleeding from the gums, gastrointestinal tract and nose can be seen. Physical examination may demonstrate enlargement of the spleen. A typical rash occurs to do microscopic haemorrhage of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous haemorrhage into the brain causing death. Treatment with corticosteroids is generally effective. Surgical removal of the spleen (splenectomy) is reserved for some patients. Anti-platelet antibodies are detectable in some cases. It may present in either an acute or a chronic form. Acronym: ITP (20 Sep 2002) |
| isoimmune neonatal thrombocytopenia | Immune thrombocytopenia resulting from maternal-foetal platelet incompatibility. (05 Mar 2000) |
| tetraphocomelia-thrombocytopenia syndrome | <syndrome> Tar stands for thrombocytopenia (low blood platelets) and aplasia (absence) of the radius (the long bone on the thumb-side of the forearm), features characterizing this syndrome. There is phocomelia (flipper-limb) with the thumbs always present. The fibula (the smaller bone in the lower leg) is often absent. The risk of bleeding from too few platelets is high in early infancy but lessens with age. The condition is inherited in an autosomal recessive trait with one gene (on a non-sex chromosome) coming from each parent to the tar child. Alternative names include thrombocytopenia-absent radius syndrome, radial aplasia-thrombocytopenia syndrome, and tetraphocomelia-thrombocytopenia syndrome. (12 Dec 1998) |
| thrombocytopenia | <haematology> A decrease in the number of platelets in the blood, resulting in the potential for increased bleeding and decreased ability for clotting. Origin: Gr. Penia = poverty (18 Nov 1997) |
| thrombocytopenia-absent radius syndrome | <syndrome> Tar stands for thrombocytopenia (low blood platelets) and aplasia (absence) of the radius (the long bone on the thumb-side of the forearm), features characterizing this syndrome. There is phocomelia (flipper-limb) with the thumbs always present. The fibula (the smaller bone in the lower leg) is often absent. The risk of bleeding from too few platelets is high in early infancy but lessens with age. The condition is inherited in an autosomal recessive trait with one gene (on a non-sex chromosome) coming from each parent to the tar child. Alternative names include thrombocytopenia-absent radius syndrome, radial aplasia-thrombocytopenia syndrome, and tetraphocomelia-thrombocytopenia syndrome. (12 Dec 1998) |
| thrombocytopenia purpura | <haematology> In severe thrombocytopenia, bleeding into skin leads to small petechial haemorrhages. Primary thrombocytopenia purpura is of unknown cause but results from an autoimmune mechanism that causes platelet destruction. Secondary thrombocytopenic purpura may result from drug-induced type II hypersensitivity in which platelets coated with antibody to the drug (which is acting as a hapten) are destroyed in a complement mediated reaction. It can also follow a viral upper respiratory infection and may be seen in association with lupus. (15 Oct 1997) |
| essential thrombocytopenia | A primary form of thrombocytopenia, in contrast to secondary forms that are associated with metastatic neoplasms, tuberculosis, and leukaemia involving the bone marrow, or with direct suppression of bone marrow by the use of chemical agents, or with other conditions. (05 Mar 2000) |
| rabies immune globulin | Globulin fraction of pooled plasma of high anti-rabies virus titre from immunised persons. Synonym: rabies immunoglobulin. (05 Mar 2000) |
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