| IL-1 | Interleukin-1 |
|---|---|
| IL-1 | interleukin 1 |
| IL-2 | interleukin 2 |
| IL-3 | interleukin 3 |
| IL-8 | Interleukin-8 |
| IL-1 | Interleukin 1 alpha |
|---|---|
| IL-1 | Interleukin 1 beta |
| IL-1 alpha | Interleukin -1 alpha |
| IL-1 beta | interlukin-1 beta |
| IL-1 RI | IL-1 receptor |
| IL-10 | Interleukin 10 |
| IL-11 | Interleukin 11 |
| IL-12R | IL-12 receptor |
| IL-13 | Interleukin 13 |
| IL-15 | Interleukin 15 |
| IL-1 | <cytokine> A soluble protein (17 kD: 152 amino acids) secreted by monocytes, macrophages or accessory cells involved in the activation of both T-lymphocytes and B lymphocytes and potentiates their response to antigens or mitogens. Its biological effects include the ability to replace macrophage requirements for T-cell activation, as well as affecting a wide range of other cell types. at least two IL-1 genes are active and alpha and beta forms of IL-1 are recognised. It is released early in an immune system response by monocytes and macrophages. It stimulates T-cell proliferation and protein synthesis. Another effect of IL-1 is that it causes fever. See: catabolin, endogenous pyrogen. Acronym: IL-1 (12 Dec 1998) |
|---|---|
| IL-10 | <cytokine> A factor produced by Th2 helper T-cells, some B-cells and LPS activated monocytes. It is a coregulator of mast cell growth. It is produced by T-cells and B-cells and shows extensive homology with the Epstein-Barr virus bcrfi gene. Chemical name: Cytokine formation-inhibiting factor (mouse clone F115 protein moiety reduced) Acronym: IL-10 (12 Dec 1998) |
| IL-11 | <cytokine> Pleiotropic cytokine originally isolated from primate bone marrow stromal cell line that has the ability to modulate antigen-specific antibody responses, potentiate megakaryocytes, and regulate bone marrow adipogenesis. Stimulates T-cell dependent B-cell maturation, megakaryopoiesis, various stages of myeloid differentiation. Receptor probably a tyrosine kinase. Acronym: IL-11 (12 Dec 1998) |
| IL-12 | <cytokine> A 75 kD heterodimeric cytokine composed of disulfide-bonded 40 kD and 35 kD subunits that was originally identified by its ability to induce cytotoxic effector cells in synergy with less than optimal concentrations of interleukin-2. It is released by macrophages in response to infection and promotes the activation of cell-mediated immunity. Specifically, IL-12 triggers the maturation of Thl CD4 cells, specific cytotoxic T-lymphocyte responses and an increase in the activity of NK cells and consequently, it is the initiator of cell-mediated immunity. It enhances the lytic activity of NK cells, induces interferon production, stimulates the proliferation of activated T-cells and NK cells. Is secreted by human B lymphoblastoid cells (NC 37). May play a role in controlling immunoglobulin isotype selection as it also inhibits IgE synthesis (even in the presence of anti-IFN monoclonal antibody) and as a growth factor for activated CD4+ and CD8+ T-cells independently of interleukin-2, and for CD56+ NK cells but not resting peripheral blood mononuclear cells or resting or activated tonsillar B-cells. It is likely that interleukin 12 has a major role in protective immunity against viruses and is under study as an immunotherapy in HIV infection. Formerly referred to as cytotoxic lymphocyte maturation factor. Acronym: IL-12 (12 Dec 1998) |
| IL-13 | <cytokine> A T-lymphocyte-derived cytokine that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-lymphocytes. It appears to play a role in regulating inflammatory and immune responses and has anti-inflammatory activity. Produced by activated T-cells, inhibits IL-6 production by monocytes and also the production of other pro inflammatory cytokines such as TNF, IL-1, IL-8. Stimulates B-cells. Gene is located in cluster of genes on human chromosome 5q that also has IL-4 gene. Acronym: IL-13 (12 Dec 1998) |
| IL-14 | Cytokine that induces B-cell proliferation, inhibits immunoglobulin secretion, and selectively expands certain B-cell subpopulations. Acronym: IL-14 (12 Dec 1998) |
| IL-15 | Cytokine that stimulates the proliferation of T-lymphocytes and shares biological activities with il-2. Il-15 also can induce b-lymphocyte proliferation and differentiation. Acronym: IL-15 (12 Dec 1998) |
| IL-16 | Cytokine produced by activated T-lymphocytes that stimulates the migration of CD4-positive lymphocytes and monocytes. It has been reported to suppress HIV replication. (12 Dec 1998) |
| IL-2 | <cytokine> A hormone-like substance released by stimulated T lymphocytes, causes activation and differentiation of other T lymphocytes independently of antigen. A type of interleukin, a chemical messenger, a substance that can improve the body's response to disease. It stimulates the growth of certain disease-fighting blood cells in the immune system. It is secreted by Thl CD4 cells to stimulate CD8 cytotoxic T-1yrnphocytes. Interleukin 2 also increases the proliferation and maturation of the CD4 cells themselves. During HIV infection, Interleukin-2 production gradually declines. Use of interleukin 2 therapy is under study as a way to raise CD4 cell counts and restore immune function. Acronym: IL-2 (12 Dec 1998) |
| IL-3 | <cytokine> Product of mitogen activated T-cells: colony-stimulating factor for bone marrow stem cells and mast cells. A multilineage cell growth factor secreted by lymphocytes, epithelial cells, and astrocytes which stimulates clonal proliferation and differentiation of various types of blood and tissue cells. It is considered one of the haematopoietic colony-stimulating factors. Synonym: multi-CSF Acronym: IL-3 (12 Dec 1998) |
| IL-4 | <cytokine> A soluble cytokine factor produced by activated T-lymphocytes that promotes antibody production by causing proliferation and differentiation of B-cells. Interleukin-4 induces the expression of class II major histocompatibility complex and fc receptors on B-cells. It also acts on T-lymphocytes, mast cell lines, and several other haematopoietic lineage cells including granulocyte, megakaryocyte, and erythroid precursors, as well as macrophages. Acronym: IL-4 (12 Dec 1998) |
| IL-5 | <cytokine> A factor promoting eosinophil differentiation and activation in haematopoiesis. It also triggers activated B-cells for a terminal differentiation into Ig-secreting cells. Acronym: IL-5 (12 Dec 1998) |
| IL-6 | <cytokine> A cytokine that stimulates the growth and differentiation of human B-cells and is also a growth factor for hybridomas and plasmacytomas. It is produced by many different cells including T-cells, monocytes, and fibroblasts. A single chain 25 kD cytokine originally described as a pre B-cell growth factor, now known to have effects on a number of other cells including T-cells which are also stimulated to proliferate. An inducer of acute phase proteins and a colony-stimulating factor acting on mouse bone marrow. Acronym: IL-6 (12 Dec 1998) |
| IL-7 | <abbreviation> Interleukin-7. (05 Mar 2000) |
| IL-8 | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| il- |
forty-nine: being nine more than forty Illinois: a Midwest state in north-central United States
Ãâó: wordnet.princeton.edu/perl/webwn
|
|---|---|
| IL-1 |
Interleukin-1 (IL-1) is secreted by the macrophages, monocytes and dendritic cells. It is an important part of the inflammatory response. It increases the expression of adhesion factors on endothelial cells to enable transmigration of leukocytes. It also re-sets the hypothalamus thermoregulatory center, leading to an increased body temperature which expresses itself as fever. It is therefore called an endogenous pyrogen. ...
Ãâó: en.wikipedia.org/wiki/IL-1
|
| IL-1 |
interleukin-1. A type of biological response modifier that stimulates immune system cells that fight disease, and is involved in inflammatory responses. There are two forms of IL-1, IL-1 alfa and IL-1 beta. Both forms of IL-1 are produced by the body, and can also be made in the laboratory.
Ãâó: www.stjude.org/glossary
|
| IL-3 |
Interleukin-3. A type of biological response modifier (a substance that can improve the body's natural response to disease) that enhances the immune system's ability to fight tumor cells. These substances are normally produced by the body. They are also made in the laboratory for use in treating cancer and other diseases.
Ãâó: www.stjude.org/glossary
|
| IL-2 |
Interleukin-2. A type of biological response modifier (a substance that can improve the body's natural response to disease) that enhances the ability of the immune system to kill tumor cells and may interfere with blood flow to the tumor. These substances are normally produced by the body. Aldesleukin is IL-2 that is made in the laboratory for use in treating cancer and other diseases.
Ãâó: www.stjude.org/glossary
|
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|