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| MD | Doctor of Medicine [Lat. Medicinae Doctor]; magnesium deficiency; main duct; maintenance dose; major... |
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| Ig | Immuno-globulin IgA; Immuno-globulin A; (27)(30)60(100) - (170)(80)(250)380 mg/dL |
| IGA | infantile genetic agranulocytosis |
| IgA | immunoglobulin A |
| S-IgA | secretory immunoglobulin A |
| IgA-D | IgA deficiency |
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| IgA GN | IgA glomerulonephritis |
| IgA-IC | IgA immune complex |
| IgA NP | IgA nephropathy |
| IgA RF | IgA rheumatoid factor |
| IgA deficiency | A dysgammaglobulinaemia characterised by a deficiency of IgA. (12 Dec 1998) |
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| glomerulonephritis, IgA | Chronic form of glomerulonephritis characterised by recurring haematuria with only slight proteinuria and by deposits of IgA immunoglobulin in the mesangial areas of the renal glomeruli. It usually occurs in young males. (12 Dec 1998) |
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| secretory component of IgA | <immunology, protein> A polypeptide chain of about 60 kD that aids secretion of the IgA, a portion of the IgA receptor on the plasmalemma of the inner side of the epithelial cells lining the gut, which is proteolysed when the IgA receptor complex has travelled through the cell after receptor mediated endocytosis at the inner face, to the outer (luminal) face. (18 Nov 1997) |
| IgA | <immunology> Major class of immunoglobulin of external secretions in mammals, also found in serum and body fluids such as tears and saliva and in the respiratory, reproductive, urinary and gastrointestinal tracts. Immunoglobulin A protects the bodys mucosal surfaces from infection and in secretions, it is found as a dimer (400 kD) joined by a short J chain and linked to a secretory portion or transport piece. In serum found as a monomer (170 kD). Immunoglobulin A is the main mechanism for providing local immunity against infections in the gut or respiratory tract and may act by reducing the binding between an immunoglobulin A coated micro organism and a host epithelial cell. Present in human colostrum but not transferred across the placenta. Have heavy chains. (30 Mar 1998) |
| IgA nephropathy | <nephrology, pathology> This is a form of glomerulonephritis that results from the deposition of circulating IgA antibody in the kidney tissues. Inflammation of the glomerulus (glomerulonephritis) is the result. This condition may present as acute glomerulonephritis, chronic glomerulonephritis or rapidly progressive glomerulonephritis. Berger's is usually detected in an individual with one or two bouts of bloody urine (usually begins during or soon after a respiratory infection) and no other symptoms of renal disease. Only rarely, will Berger's disease permanently affect kidney function and progress to chronic renal failure. This renal disorder more commonly affects males in the 16-40 age group. Origin: Gr. Pathos = disease (27 Sep 1997) |
| IgA, secretory | The principle ig found in exocrine secretions such as milk, respiratory and intestinal mucin, saliva and tears. It is composed of two to four molecules of 7s IgA and one molecule each of j chain and secretory component (sc), also called secretory piece. Molecular weight appr. 400,000. (12 Dec 1998) |
| IgA-specific serine endopeptidase | <enzyme> Extracellular microbial enzymes whose only substrate is human IgA of the iga1 subclass; cleave the immunoglobulin at a specific internal prolyl-threonyl peptide bond in the heavy chain to yield intact faba and fca fragments; consider also EC 3.4.24.13 Registry number: EC 3.4.21.72 Synonym: immunoglobulin a(1) protease, iga1 protease, immunoglobulin a1 protease, IgA protease (26 Jun 1999) |
| linear IgA bullous disease in children | A rare self-limiting bullous disease, chiefly of the trunk, perioral, and pelvic areas, with onset in the first decade, successively less severe recurrences, and total remission at adolescence; linear epidermal basement membrane zone deposit of IgA is found in involved and in normal skin. Synonym: linear IgA bullous disease in children. (05 Mar 2000) |
| abdominal muscle deficiency syndrome | <syndrome> Congenital absence (partial or complete) of abdominal muscles, in which the outline of the intestines is visible through the protruding abdominal wall; in males, genitourinary anomalies (urinary tract dilation and cryptorchidism) are also found; genetics unclear. (05 Mar 2000) |
| adult lactase deficiency | Onset of lactase deficiency, with resulting milk intolerance and malabsorption, in adulthood. Inherited forms may not be manifested until adulthood; any process that damages the intestinal lining cells can cause lactase deficiency in adults. (05 Mar 2000) |
| alpha-1 antitrypsin deficiency | <chest medicine> Deficiency of the protease inhibitor alpha-1 antitrypsin, leads primarily to degradation of elastin of the alveolar walls, as well as other structural proteins of a variety of tissues. The lack of this protein leads to damage of various organs, but mainly to the lung and liver. symptoms may become apparent at a very early age or in adulthood, manifesting either as shortness of breath or liver related symptoms (jaundice, fatigue, fluid in the abdomen, mental changes, or gastrointestinal bleeding). There are several options for treatment of the lung disease, including replacement of the missing protein. Treatment of the liver disease is a well-timed liver transplant (12 Dec 1998) |
| alpha-1-proteinase deficiency | Absence of a serum proteinase inhibitor that may cause nodular non-suppurative panniculitis. (05 Mar 2000) |
| alpha-antitrypsin deficiency | <enzyme> A specific enzyme (alpha 1 antitrypsinase) that when absent genetically can result in panacinar emphysema (lung disease) and liver disease. There is no specific treatment for this condition other than supportive care for the liver and lung complications. Medications such as alpha-1proteinase inhibitor is given regularly to these patients. Incidence: approximately 1 in 10,000. (02 Jan 1998) |
| anaemia, iron deficiency | Deficiency of iron results in anaemia because iron is necessary to make haemoglobin, the key molecule in red blood cells responsible for the transport of oxygen. In iron deficiency anaemia, the red cells are unusally small (microcytic) and pale (hypochromic). Characteristic features of iron deficiency anaemia in children include failure to thrive (grow) and increased infections. The treatment of iron deficiency anaemia, whether it be in children or adults, is with iron and iron-containing foods. Food sources of iron include meat, poultry, eggs, vegetables and cereals (especially those fortified with iron). According to the National Academy of Sciences, the Recommended Dietary Allowances of iron are 15 milligrams per day for women and 10 milligrams per day for men. Anaemia characterised by low or absent iron stores, low serum iron concentration, elevated free erythrocyte porphorin, low transferrin saturation, elevated transferrin, low serum ferritin, low haemoglobin concentration or haematocrit, and hypochromic microcytic red blood cells. Symptoms may include pallor, angular stomatitis and other oral lesions, gastrointestinal complaints, retinal haemorrhages and exudates, and thinning and brittleness of the nails. Among the causes of iron-deficiency anaemia are inadequate iron intake, impaired iron absorption, increased blood loss and increased requirements such as infancy, pregnancy, and lactation. (12 Dec 1998) |
| antibody deficiency disease | <syndrome> Any of a group of disorders associated with a defective antibody production due to defects in the B-type lymphocyte system or in T-type lymphocytes; chief manifestation is an increased susceptibility to infection by various microorganisms. See: agammaglobulinaemia, hypogammaglobulinaemia, immunodeficiency. Synonym: antibody deficiency disease. (05 Mar 2000) |
| antibody deficiency syndrome | <syndrome> Any of a group of disorders associated with a defective antibody production due to defects in the B-type lymphocyte system or in T-type lymphocytes; chief manifestation is an increased susceptibility to infection by various microorganisms. See: agammaglobulinaemia, hypogammaglobulinaemia, immunodeficiency. Synonym: antibody deficiency disease. (05 Mar 2000) |
Synonyms : Deficiency, IgA, Deficiencies, IgA, IgA Deficiencies
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