| APRT | adenine phosphoribosyl transferase |
|---|---|
| HGPRT | hypoxanthine guanine phosphoribosyl transferase |
| PRT | Penicillium roqueforti toxin; pharmaceutical research and testing; phosphoribosyl transferase; posto... |
| GT | gait training; galactosyl transferase; gastrostomy; generation time; genetic therapy; gingiva treatm... |
| GARS | glycine amide phosphoribosyl synthetase |
| CHO/HGPRT | Chinese hamster ovary cell hypoxanthine guanine phosphoribosyl transferase |
|---|---|
| HGPRT | Hypoxanthine Guanine Phosphoribosyl Transferase |
| HPRT | Hypoxanthine phosphoribosyl transferase |
| HGPRTase | Hypoxanthine-guanine phosphoribosyl transferase |
| HGXPRTase | Hypoxanthine-guanine-xanthine phosphoribosyl transferase |
| hypoxanthine-guanine phosphoribosyl transferase | <enzyme> An enzyme which plays an important role in the making of ATP and GTP from guanine -- the only way guanine, adenine, or other purine molecules are able to become part of nucleic acids. Biologists study gene action via the incorporation of modified nitrogenous bases into DNA by manipulating the metabolic role which this enzyme plays. Similarly, the enzyme thymidine kinase is used for the same purpose by biologists because it fills the same important and unique role for the pyrimidines (thymine, cytosine, uracil, etc.). Acronym: HGPRT (09 Oct 1997) |
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| phosphoribosyl pyrophosphate | <chemical> The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides. Chemical name: alpha-D-Ribofuranose, 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate) (12 Dec 1998) |
|---|---|
| hypoxanthine-guanine phosphoribosyl tranferase marker | The gene which codes for the enzyme hypoxanthine-guanine phosphoribosyl transferase. It is a selectable marker because cells which have a defective version of this gene are resistant to poisoning by toxic purine derivatives which result from the metabolic pathway that the HGPRT enzyme catalyses. (The purine derivatives are toxic because they incorporate into DNA as a result of the HGPRT enzyme's actions). Because the defective gene cannot produce the enzyme, no toxic purine derivatives are produced, the gene can therefore be selected for. (09 Oct 1997) |
| N-(5'-phosphoribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase | <enzyme> Has beta/alpha-barrel fold structure; involved in biosynthesis of histidine Registry number: EC 5.3.1.16 Synonym: hisa gene product, pfacr isomerase, phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (26 Jun 1999) |
| acetate-succinate CoA-transferase | <enzyme> Tritichomonas and trichomonas enzyme converts acetyl-CoA and succinate to acetate and succinyl-CoA Registry number: EC 2.8.3.- Synonym: acetate-succinate coenzyme a-transferase (26 Jun 1999) |
| acyl-CoA transferase | <enzyme> Transfers CoA from succinyl-CoA to propionate, forming propionyl-CoA plus succinate Registry number: EC 2.8.3.- Synonym: propionate CoA-transferase, acyl-coenzyme a transferase (26 Jun 1999) |
| alpha2-8-KDN-transferase | <enzyme> Catalyses the transfer of deaminated neuraminic acid, kdn (2-keto-3-deoxy-d-glycero-d-galacto-nononic acid) from cmp-kdn to the non-reducing termini of oligo-polysialyl chains of polysialoglycoprotein Registry number: EC 2.4.99.- Synonym: kdn-transferase (26 Jun 1999) |
| arabinosyl-hydroxyproline transferase | <enzyme> Involved in glycoprotein synthesis in plants Registry number: EC 2.4.2.- Synonym: ar-hpt, protein-arabinosyltransferase (26 Jun 1999) |
| ATP-dependent DNA strand transferase | <enzyme> From human cell nuclei; catalyses strand exchange between homologous DNA sequences; magnesium dependent, requires ATP hydrolysis Registry number: EC 2.7.7.- Synonym: ATP-dep-DNA-str trnsfase (26 Jun 1999) |
| beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-acetylglucosaminyl transferase | <enzyme> With EC 2.4.1.148 this is called beta6-glcnac-transferase b Registry number: EC 2.4.1.102 Synonym: gal3-galnac-mucin-6-glcnac transferase, udp-glcnac-gal1-3galnac-r-(glcnac to galnac)-beta1-6glcnac transferase, core 2 glcnac transferase, core 2-n-acetylglucosaminyltransferase, core 2 beta6-gn-t (26 Jun 1999) |
| butyryl-CoA acetoacetate CoA transferase | <enzyme> Butyryl-CoA + acetoacetate yields butyrate + acetoacetyl-CoA Registry number: EC 2.8.3.- Synonym: butyryl-coenzyme a acetoacetate coenzyme a transferase (26 Jun 1999) |
| p21(ras) farnesyl-protein transferase | <enzyme> Transfers the farnesyl moiety from farnesyl pyrophosphate to a cysteine in p21(ras) proteins; composed of an alpha and a beta subunit Registry number: EC 2.5.1.- Synonym: farnesyl-protein transferase p21(ras), ras p21 farnesyl-protein transferase, protein-cysteine farnesyltransferase, pc farnesyltransferase, protein farnesyltransferase, p21(ras) farnesyltransferase, farnesyl-protein transferase-alpha, farnesyl-protein transferase-beta, ft alpha, ft beta, caax farnesyltransferase, ftase enzyme (26 Jun 1999) |
| galactosyl transferase | <enzyme> Enzyme catalysing the transfer of galactose units from the sugar nucleotide, uridine diphospho galactose UDP galactose) to an acceptor, commonly N acetyl glucosamine in a glycan chain, forming a glycosidic bond involving C1 of galactose. (18 Nov 1997) |
| glutathione S-transferase | A class of enzymes that catalyze the reaction of glutathione with an acceptor molecule (e.g., an arene oxide) to form an S-substituted glutathione; a key step in detoxification of many substances; start of the mercapturic acid pathway. Synonym: ligandin. (05 Mar 2000) |
| glutathione transferase | <enzyme> A transferase that catalyses the addition of aliphatic, aromatic, or heterocyclic radicals as well as epoxides and arene oxides to glutathione. Addition takes place at the sulfur atom. It also catalyses the reduction of polyol nitrate by glutathione to polyol and nitrite. Chemical name: RX:glutathione R-transferase Registry number: EC 2.5.1.18 (12 Dec 1998) |
| glycoprotein hormone-specific N-acetylgalactosamine transferase | <enzyme> Transfers galnac to the terminal glcnac moieties of glcnac2man3glcnac2asn Registry number: EC 2.4.1.- Synonym: ghs-acgalnh2 transferase, glycoprotein hormone galnac transferase, glycoprotein hormone - n-acetylgalactosaminyltransferase (26 Jun 1999) |
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