| hypogammaglobulinaemia | <biochemistry> Syndromes in humans and other vertebrates in which the immunoglobulin level is depressed below the normal range. Congenital, chronic and transient types are known. Origin: Gr. Haima = blood (11 Jan 1998) |
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| acquired hypogammaglobulinaemia | Heterogeneous group of immunodeficiency syndromes characterised by hypogammaglobulinaemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections. (12 Dec 1998) |
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| primary hypogammaglobulinaemia | Hypogammaglobulinaemia due to a primary immunodeficiency of immunoglobulin-forming cells (B-lymphocytes). (05 Mar 2000) |
| X-linked hypogammaglobulinaemia | A congenital, X-linked recessive, primary immunodeficiency characterised by decreased numbers (or absence) of circulating B-lymphocytes with corresponding decrease in immunoglobulins of the five classes; associated with marked susceptibility to infection by pyogenic bacteria (notably, pneumococci and Haemophilus influenzae) beginning after loss of maternal antibodies. X-linked hypogammaglobulinaemia with growth hormone deficiency, hypogammaglobulinaemia combined with a reduced number of B-cells; characterised by short stature, delayed puberty, and recurrent infections. (05 Mar 2000) |
| secondary hypogammaglobulinaemia | Immunodeficiency in which there is no evident defect in the lymphoid tissues, but rather hypercatabolism or loss of immunoglobulins such as occurs in familial idiopathic hypercatabolic hypoproteinaemia or in defects associated with the nephrotic syndrome. Synonym: secondary agammaglobulinaemia, secondary antibody deficiency, secondary hypogammaglobulinaemia. (05 Mar 2000) |
| transient hypogammaglobulinaemia of infancy | A type of primary immunodeficiency that occurs in infants of both sexes, usually before the sixth month of life, probably resulting from immaturity of lymphoid tissue. Synonym: transient agammaglobulinaemia. (05 Mar 2000) |
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