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  • Hydroxymethylglutary-CoA
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  • tris(hydroxymethyl)aminomethane buffer
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  • hydroxymethyl group
    ÇÏÀ̵å·Ï½Ã¸ÞÆ¿±â(Ðñ)
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  • active hydroxymethyl
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SHMT serine-hydroxymethyl transferase
THAM tris(hydroxymethyl)aminomethane
TRIS tris-(hydroxymethyl)-aminomethane
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hydroxymethyl 1'-hydroxy-2
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HMA 3-hydroxymethyl antipyrine
HMF 5-(Hydroxymethyl)furfural
HMUra 5-(Hydroxymethyl)uracil
HMdU 5-(hydroxymethyl)-2'-deoxyuridine
HmdUrd 5-Hydroxymethyl-2'-deoxyuridine
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 10 ÆäÀÌÁö: 1
hydroxymethyl and formyl transferases <enzyme> Enzymes that catalyze the transfer of hydroxymethyl or formyl groups.
Registry number: EC 2.1.2
(12 Dec 1998)
hydroxymethylbilane synthase <enzyme> An enzyme that catalyses the formation of hydroxymethylbilane from four molecules of porphobilinogen.
Chemical name: Porphobilinogen ammonia-lyase (polymerizing)
Registry number: EC 4.3.1.8
(12 Dec 1998)
hydroxymethyldeoxyuridinemonophosphate kinase <enzyme> An aspect of nucleoside monophosphate kinase EC 2.7.4.4
Registry number: EC 2.7.4.-
Synonym: hmdump kinase, hydroxymethyldeoxyuridine monophosphate kinase
(26 Jun 1999)
hydroxymethyldihydropterin pyrophosphokinase <enzyme> Convets 6-hydroxymethyl-7,8-dihydropterin and ATP to 6-hydroxymethyl-7,8-dihydropterin pyrophosphate and AMP
Registry number: EC 2.7.6.-
Synonym: suld gene product
(26 Jun 1999)
hydroxymethylglutaryl CoA reductases <enzyme> In the biosynthesis of cholesterol, these enzymes catalyze the reduction of one of the carboxyl groups of beta-hydroxy, beta-methylglutaryl CoA to yield mevalonic acid.4 requires NADP, EC 1.1.1.88 requires NAD.
Chemical name: (S)-Mevalonate:NAD+ oxidoreductase (CoA-acylating)
Registry number: EC 1.1.1.88
(12 Dec 1998)
hydroxymethylglutaryl-CoA reductase inhibitors Compounds that inhibit hmg-CoA reductases. They have been shown to directly lower cholesterol synthesis.
(12 Dec 1998)
hydroxymethylglutaryl-CoA synthase <enzyme> An enzyme that catalyses the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis.
Chemical name: (S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)
Registry number: EC 4.1.3.5
(12 Dec 1998)
hydroxymethylgutaryl-CoA hydrolase <enzyme> May be important in regulating mammalian cholesterol synthesis
Registry number: EC 3.1.2.5
Synonym: beta-hydroxy-beta-methylglutaryl coenzyme a hydrolase, beta-hydroxy-beta-methylglutaryl coenzyme a deacylase
(26 Jun 1999)
hydroxymethylpyrimidine kinase <enzyme> Found in E coli; catalyses th phosphorylation of 4-amino-5-hydroxymethyl-2-methylpyrimidine to 4-amino-5-phosphomethyl-2-methylpyrimidine in the presence of ATP
Registry number: EC 2.7.1.49
(26 Jun 1999)
hydroxymethyluracil DNA glycosylase <enzyme> Functions to eliminate hydroxymethyluracil from oxidatively damaged DNA
Registry number: EC 3.2.2.-
Synonym: hmu DNA glycosylase
(26 Jun 1999)
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alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase <enzyme> Involved in degradation of vitamin b6; forms acetic acid plus ammonia plus carbon dioxide plus alpha-hydroxymethyl-succinic monoaldehyde
Registry number: EC 3.5.1.-
Synonym: compound b hydrolase
(26 Jun 1999)
tris(hydroxymethyl)aminomethane <chemical> An organic amine proton acceptor. It is used in the synthesis of surface-active agent and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, is a biological buffer, and is used as an alkaliser.
Pharmacological action: buffers, excipient.
Chemical name: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
(12 Dec 1998)
tris(hydroxymethyl)methylamine <chemical> An organic amine proton acceptor. It is used in the synthesis of surface-active agent and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, is a biological buffer, and is used as an alkaliser.
Pharmacological action: buffers, excipient.
Chemical name: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
(12 Dec 1998)
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-7,8-dihydropteroate synthase <chemical> Bifunctional enzyme involved in folate biosynthesis in plants; genbank y08611 (pisum sativum)
Synonym: hppk-dhps, pppk-dhps, hydroxymethyldihydropterin-pyrophosphokinase-dihydropteroate synthase
(26 Jun 1999)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 1
  • Hydroxymethyl and Formyl Transferases - »õâ Enzymes that catalyze the transfer of hydroxymethyl or formyl groups. EC 2.1.2.
    Synonyms : Formyl Transferases, Formyltransferases, Hydroxymethyl Transferases, Hydroxymethyltransferases, Transformylase, Transformylases, Transhydroxymethylases, Transferases, Formyl, Transferases, Hydroxymethyl
  • Hydroxymethylbilane Synthase - »õâ An enzyme that catalyzes the tetrapolymerization of the monopyrrole PORPHOBILINOGEN into the hydroxymethylbilane preuroporphyrinogen (UROPORPHYRINOGENS) in several discrete steps. It is the third enzyme in the 8-enzyme biosynthetic pathway of HEME. In humans, deficiency in this enzyme encoded by HMBS (or PBGD) gene results in a form of neurological porphyria (PORPHYRIA, ACUTE INTERMITTENT). This enzyme was formerly listed as EC 4.3.1.8
    Synonyms : Hydroxymethylbilane Synthetase, Pre-uroporphyrinogen Synthetase, Preuroporphyrinogen Synthetase, Ammonia-Lyase, Porphobilinogen, Deaminase, Porphobilinogen, Porphobilinogen Ammonia Lyase, Pre uroporphyrinogen Synthetase, Synthase, Hydroxymethylbilane
  • Hydroxymethylglutaryl CoA Reductases - »õâ Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A to yield MEVALONIC ACID.
    Synonyms : 3-Hydroxy-3-methylglutaryl CoA Reductase, HMG CoA Reductase, Hydroxymethylglutaryl CoA Reductase, 3 Hydroxy 3 methylglutaryl CoA Reductase, CoA Reductase, 3-Hydroxy-3-methylglutaryl, Reductase, 3-Hydroxy-3-methylglutaryl CoA
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors - »õâ Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.
    Synonyms : Inhibitors, HMG-CoA Reductase, Inhibitors, Hydroxymethylglutaryl-CoA, Inhibitors, Hydroxymethylglutaryl-Coenzyme A, HMG CoA Reductase Inhibitors, HMG-CoA Statins, Hydroxymethylglutaryl CoA Reductase Inhibitors, Hydroxymethylglutaryl-CoA Inhibitors
  • Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent - »õâ Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH.
    Synonyms : 3-Hydroxy-3-methylglutaryl CoA-Reductase, NAD-Dependent, HMG CoA Reductase, NAD-Dependent, Hydroxymethylglutaryl CoA Reductase, NAD-Dependent, CoA-Reductase, NAD-Dependent 3-Hydroxy-3-methylglutaryl, HMG CoA Reductase, NAD Dependent
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hydroxymethyl a methyl with hydroxide replacing the hydrogen atoms
Ãâó: wordnet.princeton.edu/perl/webwn
hydroxymethylbilane synthase [EC 4.3.1.8] an enzyme of the lyase class that catalyzes the deamination and condensation of four molecules of porphobilinogen to form a linear tetrapyrrole intermediate, hydroxymethylbilane, which cyclizes to form uroporphyrinogen. Alone, the enzyme produces uroporphyrinogen I; in the presence of uroporphyrinogen synthase it produces uroporphyrinogen III, the physiologically important isomer. Deficiency of the enzyme, an autosomal dominant trait, results in acute intermittent porphyria. Called also porphobilinogen deaminase and uroporphyrinogen I synthase.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
hydroxymethylglutaryl-CoA lyase [EC 4.1.3.4] an enzyme of the lyase class that catalyzes the cleavage of 3-hydroxy-3-methylglutaryl CoA to form acetyl coenzyme A and acetoacetate. The reaction is a step in ketogenesis and in the catabolism of leucine. Deficiency of the enzyme, an autosomal recessive trait, causes 3-hydroxy-3-methylglutaricaciduria.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
hydroxymethylglutaryl-CoA reductase (NADPH) [EC 1.1.1.34] an enzyme of the oxidoreductase class that catalyzes the reduction of 3-hydroxy-3-methylglutaryl CoA to mevalonate, using NADPH as an electron donor. The reaction is a key rate-limiting step in the biosynthesis of cholesterol and the enzyme is inactivated by a specific kinase and reactivated by a specific phosphorylase.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
hydroxymethylglutaryl-CoA synthase [EC 4.1.3.5] an enzyme of the lyase class that catalyzes the condensation of acetyl coenzyme A and acetoacetyl coenzyme A to form 3-hydroxy-3-methylglutaryl CoA. A liver and kidney mitochondrial enzyme catalyzes the reaction as a step in ketogenesis; a cytosolic enzyme acts in the synthesis of cholesterol and other isoprenoids.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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hydroxymethyl a methyl with hydroxide replacing the hydrogen atoms
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