| homogentisate 1,2-dioxygenase | An iron-containing enzyme that catalyses the oxidative cleavage of the benzene ring in homogentisic acid by O2, forming 4-maleylacetoacetate; an absence or deficiency of this enzyme will result in alcaptonuria. Synonym: homogentisic acid oxidase. (05 Mar 2000) |
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Synonyms : Homogentisate Dioxygenase, Homogentisate Oxidase, Homogentisate Oxygenase, Homogentisic Acid Oxidase, 1, 2-Dioxygenase, Homogentisate, Acid Oxidase, Homogentisic, Dioxygenase, Homogentisate, Homogentisate 1, 2 Dioxygenase, Oxidase, Homogentisate
| homogentisate |
the anionic form of homogentisic acid.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| homogentisate 1,2-dioxygenase |
[EC 1.13.11.5] an enzyme of the oxidoreductase class that catalyzes the oxidation of homogentisate to form 4-methylacetoacetate as a step in the degradation of tyrosine and phenylalanine. Deficiency of the enzyme, an autosomal recessive trait, causes alkaptonuria.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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