| HDAC | 1/histone deacetylase |
|---|---|
| AHA | Anti-histone antibodies |
| H1 | Histone 1 |
| HAT | Histone acetyl transferase |
| NHP | non histone proteins |
| histone bases | The alpha-amino acids arginine, histidine, and lysine, which are basic by virtue of the presence in the side chains of a guanidine, imidazole, and amine group, respectively; the term "hexone" is a misnomer since histidine does not have six carbons. (05 Mar 2000) |
|---|
| mannich bases | Ketonic amines prepared from the condensation of a ketone with formaldehyde and ammonia or a primary or secondary amine. A mannich base can act as the equivalent of an alpha,beta unsaturated ketone in synthesis or can be reduced to form physiologically active amino alcohols. (12 Dec 1998) |
|---|---|
| schiff bases | Condensation products of aromatic amines and aldehydes forming azomethines substituted on the n atom, containing the general formula r-n:chr. (12 Dec 1998) |
| denture bases | The part of a denture that overlies the soft tissue and supports the supplied teeth and is supported in turn by abutment teeth or the residual alveolar ridge. It is usually made of resins or metal or their combination. (12 Dec 1998) |
| ointment bases | Various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons; vehicles for medicinal substances intended for external application; there are four classes: hydrocarbon base, absorption base, water-removable base and water-soluble base; several are also emollients. (12 Dec 1998) |
| ADP ribose-histone hydrolase | <enzyme> Splits bond between ADP ribose and histone Registry number: EC 4.2.99.- Synonym: ADP-ribosyl histone splitting enzyme, ADP-ribosyl protein lyase (26 Jun 1999) |
| calcium-calmodulin-activated histone 3 arginine kinase | <enzyme> From nuclear extracts of dividing and quiescent rat heart endothelial cells; represents a new class of ca-cam-dependent kinases which phosphorylate arg Registry number: EC 2.7.10.- Synonym: ca(2+)-calmodulin-activated histone 3 arg kinase, ca-cam h3 kinase (26 Jun 1999) |
| chromosomal proteins, non-histone | Nucleoproteins which in contrast to histones are acid insoluble. They are involved in chromosomal functions; e.g. They bind selectively to DNA, stimulate transcription resulting in tissue-specific RNA synthesis and undergo specific changes in response to various hormones or phytomitogens. (12 Dec 1998) |
| histone | <molecular biology> Protein found in the nuclei of all eukaryotic cells where they are complexed to DNA in chromatin and chromosomes. They are of relatively low molecular weight and are basic, having a very high arginine/lysine content. They are highly conserved and can be grouped into five major classes. Two copies of H2A, H2B, H3 and H4 bind to about 200 base pairs of DNA to form the repeating structure of chromatin, the nucleosome, with H1 binding to the linker sequence. They may act as non-specific repressors of gene transcription. (18 Nov 1997) |
| histone deacetylase | <enzyme> Hydrolyzes n-acetyl groups on histones. Registry number: EC 3.5.1.- (12 Dec 1998) |
| histone gene | A histone gene is any gene which codes for histone proteins. (Histones help compact DNA so that it will fit into an eukaryotic cells nucleus). (09 Oct 1997) |
| histone h2b kinase | <enzyme> 96 kD serine kinase from xenopus that phosphorylates histone h2b; a component or target of the raf-mek-erk pathway Registry number: EC 2.7.1.- Synonym: p96(h2bk) (26 Jun 1999) |
| histone-lysine n-methyltransferase | <enzyme> An enzyme that catalyses the methylation of the epsilon-amino group of lysine residues in proteins to yield epsilon mono-, di-, and trimethyllysine. Chemical name: S-Adenosyl-L-methionine:histone-L-lysine N(6)-methyltransferase Registry number: EC 2.1.1.43 (12 Dec 1998) |
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