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HMP Shunt Hexose Mono-Phosphate Shunt
HDP hexose diphosphate; high-density polyethylene; hydrogen diphosphonate; hydroxydimethylpyrimidine
HMP hexose monophosphate pathway; hot moist packs
HMPS hexose monophosphate shunt
HMS hexose monophosphate shunt; hypermobility syndrome
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HMP Hexose monophosphate
HMP Hexose monophosphate pathway
HMPS Hexose monophosphate shunt
HMS Hexose-monophosphate shunt
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  • hexose monophosphate shunt
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hexose-1-phosphate uridylyltransferase <enzyme> An enzyme that catalyses the transfer of ump from udpglucose to galactose 1-phosphate, forming udpgalactose and glucose 1-phosphate. Deficiency in this enzyme is the major cause of galactosaemia.
Chemical name: UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase
Registry number: EC 2.7.7.12
(12 Dec 1998)
udpglucose-hexose-1-phosphate uridylyltransferase <enzyme> An enzyme that catalyses the transfer of ump from udpglucose to galactose 1-phosphate, forming udpgalactose and glucose 1-phosphate. Deficiency in this enzyme is the major cause of galactosaemia.
Chemical name: UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase
Registry number: EC 2.7.7.12
(12 Dec 1998)
utp-hexose-1-phosphate uridylyltransferase <enzyme> An enzyme that catalyses the synthesis of udpgalactose from utp and galactose-1-phosphate. It is present in low levels in foetal and infant liver, but increases with age, thereby enabling galactosaemic infants who survive to develop the capacity to metabolise galactose.
Chemical name: UTP:alpha-D-hexose-1-phosphate uridylyltransferase
Registry number: EC 2.7.7.10
(12 Dec 1998)
galactose-1-phosphate uridylyltransferase <enzyme> An enzyme catalyzing the reaction of UTP and alpha-d-galactose 1-phosphate to form UDPgalactose and pyrophosphate, the second and most important step in the metabolism of d-galactose; a deficiency of this enzyme results in an accumulation of galactose, galactose-1-phosphate, and galactitol.
(05 Mar 2000)
glucose-1-phosphate uridylyltransferase <enzyme> An enzyme that activates d-glucose by reacting d-glucose 1-phosphate with UTP, producing pyrophosphate and UDP glucose; a crucial step in glycogen biosynthesis.
(05 Mar 2000)
uridylyl removing-uridylyltransferase <enzyme> Modifies a regulatory protein, pii, which modulates an adenyltransferase which regulates E coli glutamine synthetase
Registry number: EC 2.7.7.-
Synonym: ur-ut
(26 Jun 1999)
utp-glucose-1-phosphate uridylyltransferase <enzyme> An enzyme that catalyses the formation of udpglucose from utp plus glucose 1-phosphate.
Chemical name: UTP:alpha-D-glucose-1-phosphate uridylyltransferase
Registry number: EC 2.7.7.9
(12 Dec 1998)
UTP-RNA uridylyltransferase <enzyme> Catalyses addition of single ump residue from utp to 3'-end of RNA primer
Registry number: EC 2.7.7.-
Synonym: terminal uridylyltransferase, ump transferase
(26 Jun 1999)
hexose Monosaccharide containing six carbon atoms, for example glucose, galactose, mannose.
(18 Nov 1997)
hexose monophosphate pathway <biochemistry> A pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, the final one being an oxidative decarboxylation to form a pentose phosphate.
Diverges from this when glucose-6-phosphate is oxidized to ribose 5 phosphate by the enzyme glucose-6 phosphate dehydrogenase. This step reduces NADP to NADPH, generating a source of reducing power in cells for use in reductive biosyntheses.
In plants, part of the pathway functions in the formation of hexoses from carbon dioxide in photosynthesis. Also important as source of pentoses, for example for nucleic acid biosynthesis. This pathway is the main metabolic pathway in neutrophils, congenital deficiency in the pathway produces sensitivity to infection.
Alternative metabolic route to Embden Meyerhof pathway for breakdown of glucose.
(18 Nov 1997)
hexose monophosphate shunt The main metabolic pathway in activated neutrophils, rendering them relatively insensitive to inhibitors of oxidative phosphorylation. Congenital deficiency of the first enzyme in the shunt, glucose 6 phosphate dehydrogenase, produces a sensitivity to infection similar to that seen in chronic granulomatous disease.
(18 Nov 1997)
hexose monphosphate pathway A metabolic pathway present in a wide range of prokaryotic and eukaryotic microorganisms as well as in plants and animals, it involves the oxidative decarboxylation of glucose-6-phosphate, via 6 phosphogluconate, to ribulose 5-phosphate, followed by a series of reversible, non-oxidative interconversions whereby hexose and triose phosphates are formed from pentose phosphates.
(09 Oct 1997)
hexose phosphatase <enzyme> May be an aspect of acid phosphatase, EC 3.1.3.2
Registry number: EC 3.1.3.-
(26 Jun 1999)
hexose phosphate synthetase <enzyme> Ribulosephosphate formaldehyde gives d-erythro-l-glycero-3-hexulose
Registry number: EC 4.1.2.-
Synonym: 3-hexulose phosphate synthase, d-arabino-3-hexulose 6-phosphate formaldehyde-lyase, 3-hexulosephosphate synthase, d-arabino-3-hexulose-6-phosphate-lysase, hexulose-6-phosphate synthase, hump synthase
(26 Jun 1999)
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hexose 1-phosphate uridylyltransferase UDPglucose–hexose-1-phosphate uridylyltransferase.
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