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"helper phage"¿¡ ´ëÇÑ °Ë»ö °á°úÀÔ´Ï´Ù. °Ë»ö °á°ú º¸´Â µµÁß¿¡ Tab ۸¦ ´©¸£½Ã¸é °Ë»ö âÀÌ ¼±Åõ˴ϴÙ.
¾Ë±â½¬¿î ÀÇÇпë¾îÇ®ÀÌÁý, ¼­¿ïÀÇ´ë ±³¼ö ÁöÁ¦±Ù, °í·ÁÀÇÇÐ ÃâÆÇ À¯»ç °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
¿µ¹® phage ÇÑ±Û ÆÄÁö
¼³¸í   
  ¼¼±ÕÀ» ¿ëÇØ½Ã۴ ¹ÙÀÌ·¯½º. *¹ÚÅ׸®¿ÀÆÄÁö ÂüÁ¶.
´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • helper phage
    µµ¿òÆÄÁö, Á¶·ÂÆÄÁö
´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 14 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • helper cell
    µµ¿ò¼¼Æ÷, Á¶·Â¼¼Æ÷
  • helper cell activity
    µµ¿ò¼¼Æ÷Ȱ¼º
  • helper virus
    º¸Á¶¹ÙÀÌ·¯½º
  • T helper cell
    Tµµ¿ò¼¼Æ÷
  • defective phage
    °á¼ÕÆÄÁö
  • donor-specific phage
    Á¦°øÀÚÆ¯ÀÌÆÄÁö, °ø¿©ÀÚÆ¯ÀÌÆÄÁö
  • inducible phage
    À¯¹ßÆÄÁö
  • latent phage
    ÀáÀçÆÄÁö
  • phage
    ÆÄÁö
  • phage genome
    ÆÄÁöÀ¯Àüü
  • temperate phage
    ¿Â¼øÆÄÁö
  • temperature-sensitive phage
    ¿Âµµ¹Î°¨ÆÄÁö
  • vegetative phage
    Áõ½ÄÇüÆÄÁö
  • virulent phage
    µ¶¼ºÆÄÁö, ¿ë±Õ¼ºÆÄÁö
´ëÇÑÀÇÇù Çʼö ÀÇÇпë¾îÁý »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • phage
    ÆÄÁö
¿¾ ´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • helper phage
    º¸Á¶ÆÄÁö, Á¶·ÂÆÄÁö
¿¾ ´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • helper cell activity
    µµ¿ò¼¼Æ÷´É, Á¶·Â¼¼Æ÷´É
  • helper cell
    µµ¿ò¼¼Æ÷, Á¶·Â¼¼Æ÷
  • helper virus
    º¸Á¶¹ÙÀÌ·¯½º, Á¶·Â¹ÙÀÌ·¯½º
  • phage conversion
    ÆÄÁöÀüȯ, ÆÄÁö±³È¯
  • defective phage
    °á¼ÕÆÄÁö
  • donor-specific phage
    Á¦°øÃ¼Æ¯ÀÌÆÄÁö, ÁÖ°ÔÆ¯ÀÌÆÄÁö
  • phage genome
    ÆÄÁöÀ¯Àüü
  • inducible phage
    À¯¹ß°¡´ÉÆÄÁö
  • latent phage
    ÀáÀçÆÄÁö
  • phage map
    ÆÄÁöÀ¯ÀüÀÚÁöµµ
  • phage
    ÆÄÁö
  • phage plaque-forming unit
    ÆÄÁö¿ë±ÕÇü¼º´ÜÀ§, ÆÄÁöÇöóÅ©Çü¼º´ÜÀ§
  • temperate phage
    ÀáÀçÆÄÁö, ¿Â¼øÆÄÁö
  • temperature-sensitive phage
    ¿Âµµ¹Î°¨ÆÄÁö
  • transducing phage
    ÇüÁúµµÀÔÆÄÁö
¿¾ ´ëÇÑÀÇÇù 2 ÀÇÇпë¾î »çÀü °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • helper phage
    Á¶·ÂÆÄÁö
¿¾ ´ëÇÑÀÇÇù 2 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • Helper T cells
    º¸Á¶ T¼¼Æ÷
  • helper T cell
    Á¶·ÂT¼¼Æ÷, º¸Á¶T¼¼Æ÷
  • helper T cell
    º¸Á¶ T¼¼Æ÷
  • helper T cell
    º¸Á¶ T ¼¼Æ÷
  • helper cell
    º¸Á¶¼¼Æ÷
  • helper cell
    Á¶·Â¼¼Æ÷, º¸Á¶¼¼Æ÷
  • helper cell activity
    Á¶·Â¼¼Æ÷´É, º¸Á¶¼¼Æ÷´É
  • helper virus
    º¸Á¶¹ÙÀÌ·¯½º.
  • helper virus
    Á¶·Â¹ÙÀÌ·¯½º
  • helper virus
    º¸Á¶¹ÙÀÌ·¯½º.
  • helper/inducer
    º¸Á¶(ÀÎÀÚ)/À¯¹ß<À¯µµ>(ÀÎÀÚ)
  • inducible phage
    À¯¹ß°¡´ÉÆÄÁö
  • phage
    ÆÄÁö.
  • phage
    ÆÄÁö
  • phage conversion
    ÆÄÁö±³È¯(¡­Îßüµ).
¿¾ ´ëÇÑÀÇÇù 3 ÀÇÇпë¾î »çÀü °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • helper phage
    Á¶·ÂÆÄÁö
¿¾ ´ëÇÑÀÇÇù 3 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • phage, helper
    º¸Á¶ÆÄÁö, Á¶·ÂÆÄÁö
  • autoimmune disease,bypass of t-helper cell(low zone)
    T-º¸Á¶¼¼Æ÷ ³»¼º ¿ìȸ(¡­ÜÍð¾á¬øàÒ±àõéæüß)
  • cell, helper
    Á¶·Â¼¼Æ÷, º¸Á¶¼¼Æ÷
  • helper T cell
    Á¶·ÂT¼¼Æ÷, º¸Á¶T¼¼Æ÷
  • helper T cell
    º¸Á¶ T ¼¼Æ÷
  • helper T cell
    º¸Á¶ T¼¼Æ÷
  • helper cell
    Á¶·Â¼¼Æ÷, º¸Á¶¼¼Æ÷
  • helper cell
    º¸Á¶¼¼Æ÷
  • helper cell activity
    Á¶·Â¼¼Æ÷´É, º¸Á¶¼¼Æ÷´É
  • helper virus
    Á¶·Â¹ÙÀÌ·¯½º
  • helper virus
    º¸Á¶¹ÙÀÌ·¯½º.
  • helper virus
    º¸Á¶¹ÙÀÌ·¯½º.
  • helper/inducer
    º¸Á¶(ÀÎÀÚ)/À¯¹ß<À¯µµ>(ÀÎÀÚ)
  • t helper cell
    T º¸Á¶¼¼Æ÷ (ÜÍð¾á¬øà)
  • conversion, phage
    ÆÄÁöÀüȯ
´ëÇÑ»ýÈ­ÇкÐÀÚ»ý¹°ÇÐȸ ¿ë¾î »çÀü °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • helper phage
    µµ¿òÀÌ ÆäÀÌÁö
´ëÇÑ»ýÈ­ÇкÐÀÚ»ý¹°ÇÐȸ ¿ë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • helper factor
    µµ¿òÀÌ ÀÎÀÚ(ì×í­)
  • helper T cell
    µµ¿òÀÌ T ¼¼Æ÷(á¬øà)
  • helper virus
    µµ¿òÀÌ ¹ÙÀÌ·¯½º
  • T cell helper
    T ¼¼Æ÷(á¬øà)µµ¿òÀÌ
  • converting phage
    Àüȯ(ï®üµ) ÆäÀÌÁö
  • cryptogenic phage
    ÀáÀç¿ø(íÖî¤ê«) ÆäÀÌÁö
  • DNA phage
    DNA ÆäÀÌÁö (ÔÒ) a DNA-containing phage
  • filamentous phage
    Çʶó¸àÆ®Çü(û¡) ÆäÀÌÁö
  • homoimmune phage
    µ¿Á¾¸é¿ª(ÔÒðúØóæ¹) ÆäÀÌÁö
  • phage
    ÆäÀÌÁö
  • phage conversion
    "ÆäÀÌÁö Àüȯ(ï®üµ), ÆäÀÌÁö º¯È¯(ܨüµ)"
  • phage cross
    ÆäÀÌÁö ±³Â÷(Îßó©)
  • phage induction
    ÆäÀÌÁö À¯µµ(ë¯Óô)
  • phage lambda
    ¶÷´Ù ÆäÀÌÁö
  • phage lysate
    ÆäÀÌÁö ¿ëÇØ¹°(éÁú°Úª)
KMLE ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
SPL skin potential level; sound pressure level; splanchnic; spontaneous lesion; staphylococcal phage lys...
Tb Tbilisi [phage]; terbium; tubercle bacillus; tuberculosis
Th cell helper T cell(= T4 cell)
CD4 HIV helper cell count
CTh carrier-specific T-helper [cell]
KMLE ÀÚµ¿ÃßÃâ ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
PT Phage Type
PT 4 Phage type 4
HTL Helper T lymphocyte
HTLp Helper T lymphocyte precursor
HC Helper component
°æºÏ´ë Ä¡°ú´ëÇÐ ±¸°­³»°ú ±³½Ç »çÀü À¯»ç °Ë»ö °á°ú : 8 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
    ¼³¸í
  • helper cell activity
    ÇïÆÛ ¼¼Æ÷ Ȱ¼º
  • helper virus
    º¸Á¶ ¹ÙÀÌ·¯½º
    ¹ÙÀÌ·¯½º À¯ÀüÀÚÀÇ È°¼ºÀ» Á¦°øÇϰųª º¹¿ø½ÃŰ°Å³ª ȤÀº °áÇÔ ¹ÙÀÌ·¯½º¿¡°Ô ´Ü¹é ¿ÜÇǸ¦ ¸¸µå´Â ´É·ÂÀ» Á¦°øÇÔÀ¸·Î½á, °áÇÔ ¹ÙÀÌ·¯½ºÀÇ Áõ½ÄÀ» µµ¿ÍÁÖ´Â ¹ÙÀÌ·¯½º.
  • T-helper
    T Á¶ÀÀ
  • donor-specific phage
    °ø¿©±Õ ƯÀÌ ÆÄÁö
  • lambda phage
    ¶÷´Ù ÆÄ¾ÆÁö
  • phage
    ÆÄ¾ÆÁö
  • phage typing
    ÆÄ¾ÆÁö Çü¹ú, ÆäÀÌÁö Çü
    ÆÄÁö¿¡ ´ëÇÑ °¨¼ö¼º À¯¹«¿¡ µû¶ó ¼¼±ÕÀ» ºÐ·ù, Çüº°ÇÏ´Â ¹æ¹ýÀ» ÆÄÁöÇüº°À̶ó°í ÇÑ´Ù. Àü¿° °æ·Î¸¦ Á¶»çÇÏ´Â µîÀÇ ¿ªÇÐÀû ¿¬±¸¿¡ ÀÌ¿ëµÇ°í ÀÖ´Ù. ÆÄÁö °¨¼ö¼ºÀ» Á¶»çÇÏ´Â °æ¿ì¿¡´Â ÀϹÝÀûÀ¸·Î ¼¼±ÕÀ» ÆòÆÇ ¹èÁö¿¡ ½É¾î ±× À§¿¡ Àû´ç ³óµµÀÇ ÆÄÁö¾×À» ÇÑ ¹æ¿ï ¶³¾î¶ß·Á ¹è¾çÇØ¼­, ±× ºÎºÐÀÇ ¿ë±ÕÀÇ À¯¹«¿¡ ÀÇÇØ¼­ ÆÇÁ¤ÇÑ´Ù. Æ÷µµ ±¸±ÕÀÇ ÆÄÁö Çüº°À» Àß È®¸³µÇ¾î ÀÖÀ¸¸ç ¿ë±ÕÀÇ ÆÐÅÏ¿¡ µû¶ó¼­ 1, 2, 3, 4 ¹× È¥ÇÕ±ºÀ¸·Î ºÐ·ùµÇ°í ÀÖ´Ù. Çüº° ºÒ´ÉÇÑ ±ÕÁÖµµ ÀÖ´Ù. ±× ¿Ü¿¡ À导ÇÁ½º±Õ, µðÇÁÅ׸®¾Æ±Õ, ·»¼­±¸±Õ, ÄÝ·¹¶ó±Õ, Ç×»ê±Õ µî¿¡ ´ëÇØ¼­µµ ½ÃµµµÇ°í ÀÖ´Ù.
  • wear phage
    ±³¸ð»ó
    ÀúÀÛ, ¿¬ÇÏ, ÀÚÀÛ È¸·Î ¸»±â¿¡ À־ Ä¡¾Æ Á¢ÃËÀ̳ª À½½ÄÀÇ ¸¶¸ð ÀÛ¿ë ¶§¹®¿¡ ±³ÇÕ ¸é¿¡ ³ªÅ¸³ª´Â ±³¸ð. ´Ù³â°£ ÇϾǰñÀÌ ÇàÇÏ´Â ±â´ÉÀû ¶Ç´Â ºñ±â´ÉÀû ¿îµ¿À¸·Î ³ªÅ¸³ª¸ç, ±³ÇÕ¸éÀÇ ±³¸ð´Â ¿¬·ÉÀûÀÎ º¯È­ ¶§¹®ÀÌ´Ù.
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
helper phage A virus which helps a separate and unrelated defective virus reproduce by infecting the same host cell that is already occupied by the defective virus and providing the proteins which the defective virus is missing and needs to complete its life cycle.
(09 Oct 1997)
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
helper cell A subset of T lymphocytes that acts in cooperation with B lymphocytes to permit antibody formation.
Synonym: inducer cell.
(05 Mar 2000)
helper factor A group of factors apparently produced by helper T lymphocytes that act specifically or non-specifically to transfer T-cell help to other classes of lymphocytes. The existence of specific T-cell helper factor is uncertain.
(18 Nov 1997)
helper t lymphocyte <haematology, immunology> A type of white blood cell produced by the thymus gland whose presence is necessary for normal levels of antibodies to be produced by B lymphocytes, both in the body (in vivo) and in experimental situations (in vitro).
(09 Oct 1997)
helper virus <virology> A virus that will allow the replication of a co-infecting defective virus by producing the necessary protein.
(18 Nov 1997)
helper viruses Viruses which enable defective viruses to replicate or to form a protein coat by complementing the missing gene function of the defective (satellite) virus. Helper and satellite may be of the same or different genus.
(12 Dec 1998)
t4 helper lymphocyte A specific type of lymphocyte, derived from the thymus gland, that plays an important role in cellular immunity. T4 lymphocytes (CD4 cells) are decreased (absolute counts less than 200) in patients with AIDS resulting in compromised immune function.
(27 Sep 1997)
T helper cell <haematology, immunology> Sets of T lymphocytes that specifically are involved in the differentiation of B lymphocytes into antibody secreting cells. Loss of T helper cells, as in HIV infection, leads to immunosuppression. There is also T-cell help of T-cell function. TH1 and TH2 are now recognised, TH1 helping with cellular, TH2 with humoural immunity.
(16 Dec 1997)
t-helper cell Immune cells that are triggered by antibodies to seek and attack invading organisms. Cells called macrophanges summon t-helper cells to the site of the infection and present a protruding antigen onto which the t-helper cell locks, thus recognizing the invading substance. The t4-helper cell then reproduces and secretes its potent lymphokine hormones that stimulate B-cell production of antibodies; signal natural killer or cytotoxic (cell-killing) T-cells; and summon more macrophanges to the site of the infection. T-helper cells are also called t4 cells and are normally twice as common as t8 cells. If a person has aids, the proportion of t4 to t8 cells is often reversed.
(12 Dec 1998)
T helper cells A subset of lymphocytes that secrete various cytokines that regulate the immune response.
(05 Mar 2000)
T-lymphocytes, helper-inducer Subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either t or b) to initiate a variety of immune functions. For example, helper-inducer T-cells cooperate with B-cells to produce antibodies to thymus-dependent antigens and with other subpopulations of T-cells to initiate a variety of cell-mediated immune functions.
(12 Dec 1998)
Friend helper virus <virology> Mouse (lymphoid) leukaemia virus present in stocks of Friend virus, that was believed at one time to assist its replication. Molecular cloning of Friend virus has since shown that it is nondefective.
(18 Nov 1997)
b phage b corynebacteriophage
virulent phage mutant A mutant of a phage that is unable to establish lysogeny.
(05 Mar 2000)
charon phage A cloning vector made from the virus bacteriophage lambda that is used to clone DNA.
(09 Oct 1997)
phage 1. Synonym for bacteriophage.
2. <suffix> Eating, devouring.
Origin: L. Phagedaena, Gr Phago, To eat.
(20 Jun 2000)
ÇÑ¿µ/¿µÇÑ »çÀü À¯»ç °Ë»ö °á°ú : 3 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • phage
    =bacteriophage
  • helper
    ¿øÁ¶ÀÚ
  • helper
    µ½´Â(µµ¿òÀÌ µÇ´Â)»ç¶÷(°Í);°Åµå´Â »ç¶÷;Á¶¼ö(assistant);Çù·ÂÀÚ;¿øÁ¶ÀÚ;ÁöÁöÀÚ;±¸Á¶ÀÚ;À§¾ÈÀÚ
ÀÌ ¾Æ·¡ ºÎÅÍ´Â °á°ú°¡ ¾ø½À´Ï´Ù.
KMLE ¾àǰ/ÀǾàǰ ¸ÂÃã °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
  • Á¦Ç°¸í
    ¼ººÐ/ÇÔ·®
    ±¸ºÐ/º¸Çè±Þ¿©
KMLE ¾àǰ/ÀǾàǰ À¯»ç °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
  • Á¦Ç°¸í
    ¼ººÐ/ÇÔ·®
    ±¸ºÐ/º¸Çè±Þ¿©
¾Ë±â½¬¿î ÀÇÇпë¾îÇ®ÀÌÁý, ¼­¿ïÀÇ´ë ±³¼ö ÁöÁ¦±Ù, °í·ÁÀÇÇÐ ÃâÆÇ ¸ÂÃã °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
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  • ¿µ¹®
    ÇѱÛ
´ëÇÑÇØºÎÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
´ëÇÑÇØºÎÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
´ëÇѽŰæ¿Ü°úÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
    ÇÑÀÚ
´ëÇѽŰæ¿Ü°úÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
    ÇÑÀÚ
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    ÇѱÛ
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  • ¿µ¹®
    ÇѱÛ
KI ÀÇÇпë¾î »çÀü °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
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    ÇѱÛ
KI ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
KMLE ÀÇÇоà¾î »çÀü ¸ÂÃã °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
KMLE ÀÚµ¿ÃßÃâ ÀÇÇоà¾î »çÀü ¸ÂÃã °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
ÀÇÇÐ³í¹® ¾àÀÚ(Pubmed/Entrez) °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 0 ÆäÀÌÁö: 1
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    ¿µ¹®
    ÇѱÛ
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    ¿µ¹®
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  • ¿µ¹®
    ÇѱÛ
    ¼³¸í
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 1
MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 1
¿ÜºÎ ¸µÅ© - Merriam-Webster's ÀÇÇлçÀü ¸ÂÃã °Ë»ö (https://www.merriam-webster.com) °á°ú: 0 ÆäÀÌÁö: 1
¿ÜºÎ ¸µÅ© - Merriam-Webster's ÀÇÇлçÀü À¯»ç °Ë»ö (https://www.merriam-webster.com) °á°ú: 0 ÆäÀÌÁö: 1
¿ÜºÎ ¸µÅ© - A.D.A.M. Medical Encyclopedia ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú: 0 ÆäÀÌÁö: 1
¿ÜºÎ ¸µÅ© - A.D.A.M. Medical Encyclopedia À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú: 0 ÆäÀÌÁö: 1
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