| Ly | a T-cell antigen used for grouping T-lymphocytes into different classes |
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| NRG | nursing resources grouping |
| haptenic inhibition | <immunology, molecular biology> Could be considered an isolated epitope: although a hapten (by definition) has an antibody directed against it, the hapten alone will not induce an immune response if injected into an animal, it must be conjugated to a carrier (usually a protein). The hapten constitutes a single antigenic determinant, perhaps the best known example is dinitro phenol (DNP) that can be conjugated to BSA and against which antiDNP antibodies are produced (antibodies to the BSA can be adsorbed out). Because the hapten is monovalent, immune complex formation will be blocked if the soluble hapten is present as well as the hapten carrier conjugate (assuming there is more than one hapten per carrier then an immune precipitate can be formed). Competitive inhibition by the soluble small molecule is sometimes referred to as haptenic inhibition and this term has carried over into lectin mediated haemagglutination where monosaccharides are added to try to block haemagglutination: the blocking sugar defines the specificity of the lectin. (18 Nov 1997) |
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| blood grouping | The classification of blood samples by means of laboratory tests of their agglutination reactions with respect to one or more blood groups. In general, a suspension of erythrocytes to be tested is exposed to a known specific antiserum; agglutination of the erythrocytes indicates that they possess the antigen for which the antiserum is specific. Certain antisera require special testing conditions. (05 Mar 2000) |
| blood grouping and crossmatching | Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion. (12 Dec 1998) |
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