| SCD | 1) Sickle Cell Disease 2) Subacute Combined Degeneration |
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| CSCD | Center for Sickle Cell Disease |
| HbS | hemoglobin S, sickle-cell hemoglobin |
| MSD | material safety data; mean square deviation; mild sickle cell disease; most significant digit; multi... |
| PSR | pain sensitivity range; perspective surface rendering; portal systemic resistance; proliferative sic... |
| PSR | Proliferative sickle retinopathy |
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| SCD | Sickle Cell Disease |
| SCA | Sickle cell anaemia |
| SCT | Sickle cell trait |
| GHb | Glycated haemoglobin |
| haemoglobin, sickle | An abnormal haemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anaemia. (12 Dec 1998) |
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| sickle cell haemoglobin | <haematology> Haemoglobin S is an abnormal version of the protein haemoglobin. The sixth amino acid of the normal beta chain, glutamic acid, is replaced by valine with gluconic acid. This mutation causes the red blood cell to take on a sickle shape, and is the cause of the sickle cell trait condition (when the individual is heterozygous for this mutant haemoglobin) and the disease of sickle cell anaemia (when the individual is homozygous for this mutant haemoglobin). (09 Oct 1997) |
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| anaemia, sickle cell | A disease characterised by chronic haemolytic anaemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for haemoglobin s. (12 Dec 1998) |
| sickle | 1. A reaping instrument consisting of a steel blade curved into the form of a hook, and having a handle fitted on a tang. The sickle has one side of the blade notched, so as always to sharpen with a serrated edge. Cf. Reaping hook, under Reap. "When corn has once felt the sickle, it has no more benefit from the sunshine." (Shak) 2. <astronomy> A group of stars in the constellation Leo. <botany> Sickle pod, a kind of rock cress (Arabis Canadensis) having very long curved pods. Origin: OE. Sikel, AS. Sicol; akin to D. Sikkel, G. Sichel, OHG. Sihhila, Dan. Segel, segl, L. Secula, fr. Secare to cut; or perhaps from L. Secula. See Saw a cutting instrument. Source: Websters Dictionary (01 Mar 1998) |
| sickle cell | <haematology, pathology> An erythrocyte that changes from the normal discoid shape to a sickled shape when the oxygen tension is low. The pesence of these cells indicates that the patient is homozygotes for the allele that codes for haemoglobin S and that the patient has sickle cell anaemia. (18 Nov 1997) |
| sickle cell anaemia | <haematology> Disease common in races of people from areas in which malaria is endemic. The cause is a point mutation in the allele that codes for the beta chain of haemoglobin with a substitution of (valine for glutamic acid at position 6. The defective haemoglobin (HbS) crystallizes readily at low oxygen tension. In consequence, erythrocytes from homozygotes change from the normal discoid shape to a sickled shape when the oxygen tension is low and these sickled cells become trapped in capillaries or damaged in transit, leading to severe anaemia. In heterozygotes, the disadvantages of the abnormal haemoglobin are apparently outweighed by increased resistance to Plasmodium falciparum malaria, probably because parasitised cells tend to sickle and are then removed from circulation. Symptoms include joint pain, acute abdominal pain, and ulcerations of the lower extremities. Origin: Gr. Haima = blood (18 Nov 1997) |
| sickle cell anaemia: bone manifestations | <radiology> 8-13% of blacks carry sickling factor, symptoms: chronic ulcers, pain crises, many infections, priapism X-ray findings: deossification due to marrow hyperplasia, decreased bone density in skull with widened diploe, H-shaped vertebrae or fish vertebrae, rib notching, thrombosis and infarction, avascular necrosis, especially femoral head, periosteal treatmentn (bone within bone), secondary osteomyelitis, Staph. Aureus greater than Salmonella, dactylitis = hand foot syndrome, growth effects, bone shortening secondary to diminished blood supply, death less than 40y (12 Dec 1998) |
| sickle cell C disease | A disease resulting from abnormal sickle-shaped erythrocytes (containing haemoglobin C and S) which appear in response to a lowering of the partial pressure of oxygen; characterised by anaemia, crises due to haemolysis or vascular occlusion, chronic leg ulcers and bone deformities, and infarcts of bone or of the spleen. (05 Mar 2000) |
| sickle cell crisis | <haematology> Disease common in races of people from areas in which malaria is endemic. The cause is a point mutation in the allele that codes for the beta chain of haemoglobin with a substitution of (valine for glutamic acid at position 6. The defective haemoglobin (HbS) crystallizes readily at low oxygen tension. In consequence, erythrocytes from homozygotes change from the normal discoid shape to a sickled shape when the oxygen tension is low and these sickled cells become trapped in capillaries or damaged in transit, leading to severe anaemia. In heterozygotes, the disadvantages of the abnormal haemoglobin are apparently outweighed by increased resistance to Plasmodium falciparum malaria, probably because parasitised cells tend to sickle and are then removed from circulation. Symptoms include joint pain, acute abdominal pain, and ulcerations of the lower extremities. Origin: Gr. Haima = blood (18 Nov 1997) |
| sickle cell dactylitis | <syndrome> Recurrent painful swelling of the hands and feet occurring in infants and young children with sickle cell anaemia. Synonym: sickle cell dactylitis. (05 Mar 2000) |
| sickle cell disease | <haematology> Disease common in races of people from areas in which malaria is endemic. The cause is a point mutation in the allele that codes for the beta chain of haemoglobin with a substitution of (valine for glutamic acid at position 6. The defective haemoglobin (HbS) crystallizes readily at low oxygen tension. In consequence, erythrocytes from homozygotes change from the normal discoid shape to a sickled shape when the oxygen tension is low and these sickled cells become trapped in capillaries or damaged in transit, leading to severe anaemia. In heterozygotes, the disadvantages of the abnormal haemoglobin are apparently outweighed by increased resistance to Plasmodium falciparum malaria, probably because parasitised cells tend to sickle and are then removed from circulation. Symptoms include joint pain, acute abdominal pain, and ulcerations of the lower extremities. Origin: Gr. Haima = blood (18 Nov 1997) |
| sickle cell prep | <haematology, investigation> A test which looks at red blood cells under the microscope to detect sickle cells after an agent which lowers the oxygen content of the sample is added. A positive test is result is determined by the presence of sickle cells. Abnormal results indicate sickle cell anaemia or sickle cell trait. (27 Sep 1997) |
| sickle cell retinopathy | A condition marked by dilation and tortuosity of retinal veins, and by microaneurysms and retinal haemorrhages; advanced stages may show neovascularization, vitreous haemorrhage, or retinal detachment. (05 Mar 2000) |
| sickle cell test | <investigation> A test which looks at red blood cells under the microscope to detect sickle cells after an agent which lowers the oxygen content of the sample is added. A positive test is result is determined by the presence of sickle cells. Abnormal results indicate sickle cell anaemia or sickle cell trait. (27 Sep 1997) |
| sickle cell-thalassaemia disease | Anaemia, clinically resembling sickle cell anaemia, in which individuals are compound heterozygous for the sickle cell gene and a thalassaemia gene; about 60 to 80% of haemoglobin is Hb S, up to 20% Hb F, and the remainder Hb anaemia. Synonym: sickle cell-thalassaemia disease. (05 Mar 2000) |
| sickle cell trait | <haematology> This condition occurs in people who have one of two possible genes (i.e., they are heterozygous forthe allele) that code for the defective haemoglobin responsible for sickle cell anaemia. The coditionis diagnosed by exposing an individual's red blood cells to a low oxygen environment, if the trait is present, the cells will turn to a sickle shape. People with this trait may suffer milder symptoms of sickle cell anaemia, or may have no symptoms. Some scientists believe the trait actually provides an evolutionary advantage in tropical environments because the slightly altered shape of the blood cells causes a person to be more resistant to malaria. (09 Oct 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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