| HA | Haemagglutination |
|---|---|
| HAI | Haemagglutination Inhibition |
| HI | Haemagglutination Inhibition |
| HA | Haemagglutination activity |
| HI | Haemagglutination inhibition test |
| haemagglutination | <haematology> Agglutination of red blood cells, often used to test for the presence of antibodies directed against red cell surface antigens or carbohydrate binding proteins or viruses in a solution. Requires that the agglutinin has at least two binding sites. (18 Nov 1997) |
|---|---|
| haemagglutination inhibition | A variation of the haemagglutination technique. Some viral antigens, when coated on erythrocytes, spontaneously cause agglutination in the absence of antibody. In these situations, the specific antigen-antibody reaction actually prevents the agglutination of reagent RBCs. Haemagglutination inhibition cannot differentiate between isotypes of specific antibodies (IgG, IgA or IgM) although positive haemagglutination inhibition analysis of specimens treated with Staphylococcus aureus Protein A (discussed above under coagglutination) to remove the IgG isotype antibodies has been used to imply the presence of specific IgM antibodies to the specific viral antigen. The crude quantitation of the specific antibodies is possible using serial dilution (titre). (05 Mar 2000) |
| haemagglutination inhibition test | <investigation> A clinical lab test used to detect the presence of a certain haemagglutinating virus or other haemagglutinin antigen based on whether the red blood cells in the sample lose the ability to clump together when the antibody to the virus or other antigen is added to it. If the virus or antigen is present, the antibody kills it and thereby stops it from being able to stick the red blood cells to each other. (09 Oct 1997) |
| haemagglutination inhibition tests | Serologic tests in which a known quantity of antigen is added to the serum prior to the addition of a red cell suspension. Reaction result is expressed as the smallest amount of antigen which causes complete inhibition of haemagglutination. (12 Dec 1998) |
| haemagglutination test | <investigation> A test in which an antigen and an antibody react to each other on the surface of a red blood cell. (09 Oct 1997) |
| haemagglutination tests | Sensitive tests to measure certain antigens, antibodies, or viruses, using their ability to agglutinate certain erythrocytes. (12 Dec 1998) |
| haemagglutination, viral | Agglutination of erythrocytes by a virus. (12 Dec 1998) |
| viral haemagglutination | The nonimmune agglutination of suspended red blood cells by certain of a wide range of otherwise unrelated viruses, usually by the virion itself but in some instances by products of viral growth, the species of erythrocyte agglutinated differing with the different viruses. See: haemagglutination inhibition. (05 Mar 2000) |
|---|---|
| passive haemagglutination | A kind of passive agglutination in which erythrocytes, usually modified by mild treatment with tannic acid or other chemicals, are used to adsorb soluble antigen onto their surface, and which then agglutinate in the presence of antiserum specific for the adsorbed antigen. Synonym: indirect haemagglutination test. (05 Mar 2000) |
| reverse passive haemagglutination | If antibodies are bonded to the surface of red blood cells haemagglutination will occur if the appropriate bi or multivalent antigen is added in soluble or microparticulate form. Used as a test for for example Hepatitis B virus in the serum. (18 Nov 1997) |
| indirect haemagglutination test | A kind of passive agglutination in which erythrocytes, usually modified by mild treatment with tannic acid or other chemicals, are used to adsorb soluble antigen onto their surface, and which then agglutinate in the presence of antiserum specific for the adsorbed antigen. Synonym: indirect haemagglutination test. (05 Mar 2000) |
| Treponema pallidum haemagglutination test | A highly sensitive and specific test for the serologic diagnosis of syphilis; tanned sheep red blood cells are coated with the antigen of Treponema pallidum and, following absorption of non-specific patient serum antibody, a positive reaction with tanned sheep red blood cells and patient serum indicates the presence of specific antibody for Treponema pallidum in patient serum. Synonym: TPHA test. (05 Mar 2000) |
| haemagglutination | agglutination of red blood cells |
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