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  • Guanylyl cyclase
    ±¸¾Æ´Ò¸±±â »çÀÌŬ·¹ÀÌÁî
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GC Guanylyl cyclase
GC-C Guanylyl cyclase C
GC-A Guanylyl cyclase-A
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guanylyl imidodiphosphate <chemical> 5'-guanylic acid, monoanhydride with imidophosphoric acid. An analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. The nucleotide is a potent stimulator of adenylate cyclase.
Synonym: GMP-p(nh)p; gpp(nh)p.
Chemical name: 5'-Guanylic acid, monoanhydride with imidodiphosphoric acid
(12 Dec 1998)
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adenylyl imidodiphosphate <chemical> 5'-adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial atpase and also inhibits ATP-dependent reactions of oxidative phosphorylation.
Chemical name: 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid
(12 Dec 1998)
guanylyl The radical of guanylic acid.
(05 Mar 2000)
guanylyl cyclase <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain.
Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD.
(18 Nov 1997)
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  • Guanylyl Imidodiphosphate - »õâ A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of adenylate cyclase.
    Synonyms : GMP-P(NH)P, Gpp(NH)p, Guanosine 5'-(Beta, Gamma-Imido)Triphosphate, Guanyl-5'-Imidodiphosphate, P(NH)PPG, Guanyl 5' Imidodiphosphate, Imidodiphosphate, Guanylyl
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