| glycosylceramidase | <enzyme> The enzyme hydrolyzing glycosyl-n-acylsphingosine to a sugar and n-acylsphingosine. It also catalyses the hydrolysis of phlorizin to phloretin and glucose. It is found in the intestinal brush border membrane often in conjunction with lactase. Chemical name: Glucosyl-N-acylsphingosine glycohydrolase Registry number: EC 3.2.1.62 (12 Dec 1998) |
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Synonyms : Glycosyl Ceramidase, Lactase-Phlorizin Hydrolase, Ceramidase, Glycosyl, Hydrolase, Lactase-Phlorizin, Hydrolase, Phlorizin, Lactase Phlorizin Hydrolase, Phloretin Glucosidase
| glycosylceramidase |
[EC 3.2.1.62] an enzyme of the hydrolase class that catalyzes the cleavage of a β-linked sugar residue from β-glycosides with large hydrophobic aglycons, such as galactosyl- and glycosylceramides and phlorizin. Such enzyme activity occurs as part of the β-glycosidase complex (q.v.), along with lactase, in the intestinal brush border membrane, where it is frequently referred to as phlorhizin hydrolase. In this context, it is sometimes described as a composite of glucosylceramidase [EC 3.2.1.45] and galactosylceramidase [EC 3.2.1.46] activities and denoted glycosylceramidase [EC 3.2.1.456].
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