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  • glycosaminoglycan
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  • glycosaminoglycan
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GAG glycosaminoglycan; group-specific antigen gene
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AGAG Acidic glycosaminoglycan
GAG Collagen and glycosaminoglycan
DHG Depolymerized holothurian glycosaminoglycan
GAG Glycosaminoglycan
GAGPS Glycosaminoglycan polysulfate
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glycosaminoglycan <biochemistry> A macromolecule found on the surface of eukaryotic cells which is thought to play a role in the cells recognition of other cells or of a substrate. It consists of a network of long, branched chains made up of repeating units of disaccharides which contain amino groups sugars, at least one of which has a negatively charged side group (carboxylate or sulphate).
Commonest are hyaluronate (D glucuronic acid N acetyl D glucosamine: MW up to 10 million), chondroitin sulphate (D glucuronic acid N acetyl D galactosamine 4 or 6 sulphate), dermatan sulphate (D glucuronic acid or L iduronic acid N acetyl D galactosamine), keratan sulphate (D galactose N acetyl D glucosamine sulphate) and heparan sulphate (D glucuronic acid or L iduronic acid N acetyl D glucosamine).
Glycosaminoglycan side chains (with the exception of hyaluronate) are covalently attached to a core protein at about every 12 amino acid residues to produce a proteoglycan, these proteoglycans are then noncovalently attached by link proteins to hyaluronate, forming an enormous hydrated space filling polymer found in extracellular matrix. The extent of sulphation is variable and the structure allows tremendous diversity.
The protein is also a component of the capsid of a retrovirus which can act as group-specific antigens to the host.
(14 Oct 1997)
glycosaminoglycans Heteropolysaccharides which contain an n-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either n-acetylglucosamine or n-acetylgalactosamine.
(12 Dec 1998)
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  • Glycosaminoglycans - »õâ Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine or N-acetylgalactosamine.
    Synonyms :
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glycosaminoglycan A polysaccharide containing aminomonosaccharide residues.
Ãâó: www.genpromag.com/Glossary~LETTER~G.html
glycosaminoglycan A type of long, unbranched polysaccharide molecule. Glycosaminoglycans are major structural components of cartilage and are also found in the cornea of the eye.
Ãâó: www.seniormag.com/conditions/cancer/cancerglossary...
glycosaminoglycan A large molecule found on the surface of membrane-encased cells that consists of a network of long, branched chains of sugars and smaller, nitrogen-containing molecules.
Ãâó: www.nigms.nih.gov/news/science_ed/chemhealth/gloss...
glycosaminoglycan Shortened to GAG. Linear long chains (polysaccharide - many sugar molecules) comprising sugar molecules arranged in repeating disaccharide (two sugar) units with up to 10-20,000 disaccharides per GAG chain. GAGs are highly charged and make up the bulk of the mass of proteoglycans. The role of a GAG depends on its nature. May or may not be sulphated, eg, hyaluronic acid (not sulphated), heparan sulfate, chondroitin sulfate. Major component of extracellular matrix.
Ãâó: www.convatec.com/en_AU/tips/dictionary/wound_care....
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